Clinical trials: Postprandial Period
Cardiometabolic Health
The InterSat Study
In response to the removal of trans fats from our foods, the food industry now uses interesterified (IE) fats. Randomly interesterified (IE) fats rich in palmitic (Europe) and stearic (North America) acids are the most commonly…
- Trial name
- InterSat (NCT04418102)
- Testing
- Palmitic acid rich interesterified fat, Stearic acid rich interesterified fat
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes Mellitus, Type 1
Management of Glycemia Following a Pizza Meal
Glycemia following pizza consumption is typically managed with a dual wave insulin bolus. This study evaluated the effect of a simple bolus on glycemia following consumption of traditionally prepared pizzas with long (22 hours)…
- Trial name
- NCT03748251
- Testing
- the patients ate a pizza that fermented for 8 hours, the patients ate a pizza that fermented for 24 hours
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Campania Luigi Vanvitelli
Obesity
Effects of Mulberry Leaf Extract Formulation on Postprandial Glycemic Levels in Obese Children and Adolescents
The study entitled "Effects of mulberry leaf extract formulationon Postprandial Glycemic Peak in Obese Children and Adolescents: A Pilot Study" aims to evaluate the improvement in glycemic and insulinemic levels produced by a…
- Trial name
- PEDRED (NCT07494253)
- Testing
- Reducose
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Bari Aldo Moro
Diabetes Mellitus, Type 1
What is the Dose Response of Varying Meal Content of Fat on Postprandial Glycaemia in Children With T1DM?
Background: Based on international evidence, current management of people with T1DM on intensive insulin therapy (IIT) use algorithms based on the meal carbohydrate content (MCC) to calculate the prandial insulin dose.
- Trial name
- REQINSOIL (NCT02371694)
- Testing
- Test drink
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Muscle Protein Synthesis, Protein Metabolism
Time Course of Postprandial Protein Metabolism
The anabolic action of 'fast' whey protein on the regulation of postprandial muscle protein synthesis has been established to be short-lived in healthy young adults.
- Trial name
- NCT04121689
- Testing
- Milk Protein Concentrate
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Diabetes Mellitus, Type 2
Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus
An AGE-rich diet can induce after 2-6 weeks persistent increases in mediators linked to vascular dysfunction (e.g. TNFα, VCAM-1) in people with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT00446810
- Testing
- Benfotiamine
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ruhr University of Bochum
Type 1 Diabetes
Evaluation of Fats on Postprandial Glucose Control
The purpose of this study is examine the effect of different fat types on postprandial glucose control in patients with type 1 diabetes.
- Trial name
- Nabucco (NCT01869790)
- Testing
- Different fat types
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Joslin Diabetes Center
Hyperlipidemias, Inflammation
The Effects of Homogenized and Unhomogenized Milk on Postprandial Metabolism in Healthy Overweight Men
The purpose of this study is to compare the effects of homogenized, unhomogenized and skimmed milk on postprandial metabolism in healthy overweight men
- Conditions
- Hyperlipidemias, Inflammation, Atherosclerosis
- Trial name
- NCT01317524
- Testing
- Homogenized milk, Unhomogenized milk, Skimmed Milk
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Postprandial Distress Syndrome
Efficacy of a Modified Banxia Xiexin Decoction for the "Wei-Pi" Syndrome (Postprandial Distress Syndrome)
The study aims to evaluate the efficacy of a modified Banxia Xiexin Decoction (BXD) for Wei-Pi through a randomized, waitlist controlled trial.
- Trial name
- NCT04398888
- Testing
- Banxie Xiexin Decoction (BXD)
- Where
- Hong Kong
- Volunteers
- 88 people
- Sponsor
- The University of Hong Kong
Diabetes, Prediabetes
The Usefulness of Postprandial Triglyceride for Assessment of Cardiovascular Risk
The hypertriglyceridemia at fasting status has been known to be an important risk factor for cardiovascular disease (CVD). Recently, postprandial triglyceride (TG) levels draw an attention as a superior predictor of CVD because…
- Trial name
- NCT01972542
- Testing
- Oral fat tolerance test
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Roux-en-Y Gastric Bypass, Obesity
Meal Glycaemic Index and Exercise After Gastric Bypass
The study will evaluate postprandial glucose excursions and gut hormone secretion after ingestion of meals with different glycaemic index (GI) values (high vs low) followed by an acute bout of exercise or rest in gastric bypass…
- Trial name
- NCT03478098
- Testing
- Low GI mealtest, Low GI mealtest and subsequent exercise, High GI mealtest
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kirstine Nyvold Bojsen-Moeller
Postprandial Hypotension, Healthy
GastroFlow: Investigation of the Gastrointestinal Blood Flow in Patients With Postprandial Hypotension
This project will describe the mechanisms of action and the relative contributions of GIP to changes in gastrointestinal blood flow induced by oral glucose and endogenous GIP with the use of a receptor antagonists GIP(3-30)NH2 in…
- Conditions
- Postprandial Hypotension, Healthy, Blood Flow
- Trial name
- Gastroflow (NCT07381816)
- Testing
- MRI + GIPR antagonist (Tool), MRI + hangrip, Saline and oral glucose
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Type II Diabetes Mellitus, Glucose Metabolism Disorders
Whey Protein Effect on Glycaemic and Appetite Responses in T2D
The current study will investigate the effect if whey protein on postprandial glycaemia and appetite in type II diabetics, assessing incretin (GLP-1, GIP), insulin, and appetite control (leptin, PYY3-36) hormone responses.
- Conditions
- Type II Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases
- Trial name
- NCT02903199
- Testing
- Whey Protein, Hydrolysed Protein
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Northumbria University
Diabetes Mellitus, Type 2, Hydroxymethylglutaryl-CoA Reductase Inhibitors
The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion
The primary objective of the present study is to evaluate the effect of HMG-CoA reductase inhibition during 14 days on the postprandial plasma GLP-1 response in healthy individuals.
- Trial name
- NCT03018444
- Testing
- Atorvastatin
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Endothelial Dysfunction, Type 2 Diabetes Mellitus
Effects of Benfotiamine and AGE on Endothelial Function in People With Diabetes
The purpose of the study is to determine whether there are differences in postprandial endothelial function following a high-AGE(Advanced Glycation End-products) meal vs. a low-AGE meal.
- Trial name
- AGE-Benfo (NCT00437008)
- Testing
- Benfotiamine 1050mg, 3 days, high-AGE vs. low-AGE meal
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Ruhr University of Bochum
Postprandial Glucose Response
Bioequivalence of a Diabetes Specific Tube Feed
Nutricia has a range of nutritionally complete tube feeds on the market including some specific for diabetes patients. A new product is currently under development.
- Trial name
- EQUIDIA (NCT05453838)
- Testing
- oral intake of one serving of the original and new product
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Glycemic Response
Assessment of the Glycemic Responses to Nutritional Products (v2.0)
This study assesses the glycemic responses to nutritional products. During a study visit fasted subjects will consume one serving of the reference product or the test product.
- Trial name
- GLIN#2 (NCT05308147)
- Testing
- First Reference product, Second Reference product, Third Reference product
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Type 1 Diabetes Mellitus
Comparison of FiAsp and Aspart During Postprandial Exercise in Adults With Type 1 Diabetes
Hypoglycemia is the main barrier for physical activity practice of patients with type 1 diabetes (T1D). For postprandial exercise, anticipation with meal insulin bolus reduction is the recommended method to reduce…
- Trial name
- NCT03659799
- Testing
- Insulin FiAsp, Insulin Aspart, 60-minutes postprandial exercise
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Cardiovascular Risk Markers, Postprandial Metabolism
Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults
The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk…
- Conditions
- Cardiovascular Risk Markers, Postprandial Metabolism, Exercise Physiology, Substrate Oxidation
- Trial name
- NCT07229963
- Testing
- Aerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
Metabolomic Response to Meal Ingestion
The investigators have recently shown that postprandial sensations correlate with changes in circulating metabolites after a meal ingestion; however this phenomenon was demonstrated with a meal load up to the level of tolerance…
- Trial name
- NCT03383250
- Testing
- Normal meal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
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