Clinical trials: Postprandial Period
Inflammation, Obesity
Impact of High-fat Meals Varying in Fatty Acid Composition on Adipose and Systemic Metabolic-inflammatory Responses
Cardiometabolic disorders are a leading cause of death worldwide. Replacing saturated fatty acids (SFA) with unsaturated fatty acids is recommended as a way of lowering cardiometabolic disease risk.
- Conditions
- Inflammation, Obesity, Inflammatory Response, Cardiovascular Diseases
- Trial name
- NCT03712579
- Testing
- SFA-Rich Meal, MUFA-Rich Meal
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Type 1 Diabetes
Pizza Leavening and Postprandial Glycemia in Type 1 Diabetes (LEAVEN)
The purpose of this study is to compare in patients with type 1 diabetes the postprandial glucose response to the consumption of three types of pizza, obtained with different leavening techniques.
- Trial name
- LEAVEN (NCT03619031)
- Testing
- LONG LEAVENING, SHORT LEAVENING, TRADITIONAL
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Federico II University
Glycemic Response
Blood Glucose Response of Processed Starch
The goal of this clinical trial is to determine the postprandial glycemic response of the two starches in humans. Participants will be asked to consume 2 test foods on 2 separate occasions and provide blood glucose samples over…
- Trial name
- NCT06048978
- Testing
- Commercial native starch without processing, Modified starch with extrusion processing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- INQUIS Clinical Research
Postprandial Inflammation
Absorption and Digestion Kinetics of Human Metabolites
The purpose of this pilot study is to evaluate the effects oral supplementation with four human metabolites (spermidine, nicotinamide, palmitoylethanolamide (PEA), and oleoylethanolamide(OEA)) at varying doses on the circulating…
- Trial name
- NCT05017428
- Testing
- Spermidine, Nicotinamide, PEA
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Type 2 Diabetes, Postprandial Lipemia
Differential Effects of Protein Quality on Postprandial Lipemia in Response to a Fat-Rich Meal in Type 2 Diabetes: Comparison of Whey, Casein, Gluten, and Cod Protein
Enhanced and prolonged postprandial triglyceride responses involve increased cardiovascular risk in type 2 diabetes. It has been demonstrated that dietary fat and carbohydrates profoundly influence postprandial…
- Trial name
- NCT00817973
- Testing
- Casein, Whey, Cod
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Aarhus University Hospital
Healthy
Effects of Intragastric Quinine, Alone or Combined With L-isoleucine, on Postprandial Glycaemic Control
In this study, participants will receive, in randomized, double-blind fashion, an intragastric bolus administration of either (i) 300 mg quinine, (ii) 5 g L-isoleucine, (iii) a combination of (i)+(ii), or (iv) control, before 350…
- Trial name
- NCT05682339
- Testing
- Quinine, L-isoleucine, Combination of quinine and L-isoleucine
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Post-prandial Glycaemic Response, Postprandial Lipids Metabolism
Postprandial Responses to Fish Intake
Fish consumption has been increasing in recent decades due to consumer interest in the positive health effects of regular food intake, among other factors.
- Conditions
- Post-prandial Glycaemic Response, Postprandial Lipids Metabolism, Postprandial Metabolism
- Trial name
- PREFish (NCT06757608)
- Testing
- Assessment of postprandial metabolism after intake of different meat
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Type 2 Diabetes, Obesity
A Study to Evaluate the Postprandial Metabolic Response After Use of Glucerna SR in Obese Type 2 Diabetes
This is a phase 4, 24-week, randomized, parallel, open-label study of a meal replacement program with Glucerna SR in obese Asian participants with type 2 diabetes.
- Trial name
- NCT00631774
- Testing
- Glucerna SR
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Healthy
Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 3.5 mg Formulation
The purpose of this study is to evaluate the pharmacokinetics of the new formulation of zolpidem hemitartarate orodispersible tablet 3.5 mg in male and female healthy volunteers.
- Trial name
- NCT02817750
- Testing
- zolpidem hemitartarate tablet 3.5 mg (fasting + post-prandial), zolpidem hemitartarate tablet 3.5 mg (post-prandial + fasting)
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Bloating, Gastrointestinal Symptoms
A Clinical Trial to Investigate the Safety and Efficacy of Bloat on Postprandial Bloating and Its Effects Over Time in Healthy Women
The goal of this clinical trial is to investigate the safety and efficacy of Bloat on postprandial bloating in healthy women. The main question it aims to answer is what is the difference in change in bloating from pre-dose…
- Conditions
- Bloating, Gastrointestinal Symptoms, Intestinal Gas
- Trial name
- NCT07370740
- Testing
- Bloat
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Arrae
Diabetes Mellitus, Type 2
Impact of High Protein and Low Carbohydrate Smoothie Drinks in Type-2 Diabetes Mellitus
We compared between a regular high protein or a high protein and low carbohydrate smoothie drinks with conventional diabetic enteral drinks (Glucerna) on glucose homeostasis, insulin and lipid metabolism in type 2 diabetic and…
- Trial name
- NCT04577274
- Testing
- smoothie with regular formulas (SM), smoothie with low carbohydrate formulas (SMLS), conventional diabetic enteral drinks (Glucerna)
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Healthy
A Randomized, Controlled, Crossover Study to Assess the Glucose and Insulin Excursions of a Test Fiber
The objective of this trial is to evaluate the postprandial glucose and insulin responses to replacing digestible carbohydrates with resistant starch type 4 (RS4) in a baked product in healthy men and women.
- Trial name
- NCT03239288
- Testing
- Control digestible carbohydrate, Test resistant starch type 4
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cargill
Type II Diabetes Mellitus
Effect of Lixisenatide on Postprandial Lipid Profile in Obese Type 2 Diabetic Patients
Primary Objective: To evaluate the ability of lixisenatide to modulate postprandial hyperlipidemia in particular, the effects on plasma changes in triglycerides.
- Trial name
- NCT02274740
- Testing
- LIXISENATIDE AVE0010, metformin
- Volunteers
- 2 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
Effect of Lixisenatide on Postprandial Plasma Glucose Compared to Sitagliptin in Combination With Insulin Glargine
Primary Objective: To demonstrate significant reduction in postprandial plasma glucose (ΔAUC0:30-4:30h) after a standardized breakfast from baseline to Day 29.
- Trial name
- NCT02200991
- Testing
- LIXISENATIDE AVE0010, Sitagliptin, Insulin glargine HOE901
- Where
- 20 sites in Japan
- Volunteers
- 136 people
- Sponsor
- Sanofi
Sarcopenia
Postprandial Amino Acid Response After Protein Consumption
Increasing muscle protein synthesis via protein-based nutrition, with or without exercise, maintains a strong, healthy muscle mass, which in turn leads to improved health, independence and functionality in older adults.
- Trial name
- PAR (NCT04935788)
- Testing
- milk protein, micellar casein, pea protein
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Diabetes Mellitus, Type 2, Metabolic Syndrome
Isomaltulose VS Sucrose - Postprandial Effect on Incretin Profile and Second Meal Effect
This study evaluates the different postprandial effect of isomaltulose and sucrose on the incretin profile and as an determinant for the second meal effect.
- Trial name
- NCT03806920
- Testing
- Intervention A, Intervention B, Intervention C
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Nutritional and Metabolic Diseases, Lipemia
Effect of Muscle Damage After Downhill Running on Postprandial Lipids
All participants underwent three experimental trials, namely downhill running (DR), level running (LR), and the control (CON) in a cross-over design. Each trial lasted for 2 days.
- Trial name
- NCT04688073
- Testing
- Exercise, Rest
- Where
- Taiwan
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Type 2 Diabetes
Preprandial Ghrelin Effect
Background and Significance: The peptide hormone ghrelin drives hunger and feeding behavior, making it a focus of obesity research.
- Trial name
- NCT02913703
- Testing
- Ghrelin, Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jenny Tong, MD, MPH
Type 2 Diabetes, Postprandial Hypotension
Acarbose, Postprandial Hypotension and Type 2 Diabetes
Postprandial hypotension carries a risk of significant morbidity and morbidity including syncope, falls, dizziness, fatigue, stroke and myocardial infarction.
- Trial name
- NCT02043886
- Testing
- Acarbose
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Obesity, Insulin Resistance
The Effects of the Food Preservative Propionic Acid in Post-prandial Metabolism
Propionic acid (PA) is used as a preservative in foods such as cheeses, baked goods, or additive for artificial fruit flavors. The U.S.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- Walnut (NCT01889446)
- Testing
- Calcium propionate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
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