Clinical trials: Postprandial Period
Overweight, Obesity
Energy Expenditure and Substrate Oxidation in a Whole Room Calorimeter
The investigators aim to establish a protocol for metabolic rate measurements obtained using continuous monitoring of oxygen consumption and carbon dioxide production in a whole room calorimeter setting.
- Conditions
- Overweight, Obesity, Body Weight
- Trial name
- NCT04061369
- Testing
- Low fat meal, Moderate fat meal, High fat meal
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Neoplasms
ABSK021 Food Effect Study in Healthy Subjects
This is a randomized, open-label, two-sequence, two-cycle, cross-over study to evaluate the relative bioavailability of ABSK021 after single-dose fasting and high-fat postprandial administration in healthy subjects
- Trial name
- NCT05280483
- Testing
- ABSK021 with fed state, ABSK021 with fasted state
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Abbisko Therapeutics Co, Ltd
Type 1 Diabetes
Closed-loop Control of Postprandial Glucose Levels in Adults With Type 1 Diabetes
Postprandial meal glucose control with closed-loop systems (CLS) still needs some improvements. In the postprandial period, sensor delay in detecting blood glucose rise after a meal together with delays in insulin absorption…
- Trial name
- NCT02416765
- Testing
- 15-hour intervention, Insulin (Lispro, Aspart or guilisine), Glucagon (Eli Lilly)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Protein Metabolism
Effects of Protein Type and Mineral Form on Amino Acid Availability
To compare postprandial plasma amino acid availability, expressed as incremental area under the curve (iAUC), over a 6 hour period following ingestion of 25 g of different protein isolates in healthy, young adults.
- Trial name
- ProMin (NCT07677098)
- Testing
- Protein beverage
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Inflammation, Obesity
Impact of Dairy Products on Postprandial Inflammation
The study will quantitatively evaluate the systemic, postprandial inflammatory and metabolic response to the ingestion of three different meals in obese subjects.
- Conditions
- Inflammation, Obesity, Nutritional Intervention
- Trial name
- NCT01885416
- Testing
- consumption of test meal based on dairy products, consumption of high fat test meal without dairy products, consumption of high fat test meal with dairy products
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Agroscope Liebefeld-Posieux Research Station ALP
Type 1 Diabetes
Extended Bolus for Meals in a Closed-loop System
This study aims to evaluate whether the use of an extended bolus will improve glucose control with high-fat high protein meals using a closed-loop system.
- Trial name
- NCT05454891
- Testing
- Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulin, Tandem t:slim X2 insulin pump: Standard bolus of insulin then extended bolus of insulin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Overweight
Goji Berries and Energy Expenditure
Effects of foods or food substances on energy expenditure are of particular interest, because of the increasing prevalence of obesity and its consequent metabolic diseases like type II diabetes and fatty liver disease, all risk…
- Trial name
- NCT02779985
- Testing
- Lycium Barbarum mixed meal, Control mixed meal
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Ketosis
The Effect of a Ketone Drink on Liver Glucose Production in People With Type 2 Diabetes
What is the effect of a ketone drink on liver glucose production, and postprandial glycemia, in people with type 2 diabetes.
- Trial name
- KES2 (NCT05518448)
- Testing
- Ketone - beta-hydroxybutyrate (β-OHB)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Exeter
Postprandial IHL and IMCL Dynamics
Postprandial IHL and IMCL Measured With Proton Magnetic Resonance Spectroscopy
The major research objective is to assess the potential of Proton Magnetic Resonance Spectroscopy to follow Intrahepatic lipid and Intramyocellular lipid dynamics after a single meal.
- Trial name
- NCT01709643
- Testing
- High fat breakfast, HF breakfast with protein
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cystic Fibrosis
Gut Imaging for Function & Transit in Cystic Fibrosis Study 1
Many people with Cystic Fibrosis (CF) are troubled by symptoms from their stomach and bowels: their gastrointestinal (GI) tract.
- Trial name
- GIFT-CF1 (NCT03566550)
- Testing
- MRI scans
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Type2 Diabetes
Effect of Alirocumab on Postprandial Hyperlipemia in Patients With Type 2 Diabetes
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged over the past decade as a post-transcriptional regulator of the LDL receptor (LDL-R). PCSK9 acts as an endogenous natural inhibitor of the LDL-R pathway.
- Trial name
- EUTERPE (NCT03344692)
- Testing
- Alirocumab
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Nantes University Hospital
Hyperglycemia, Postprandial, Healthy
Effects of Enriched Fruit Juice on Blood Glucose Levels After a Meal in Healthy Subjects
Results from a large number of studies in humans have shown that diets rich in foods that give lower glucose response bring lower risk of type 2 diabetes.
- Trial name
- PolyGlucHeal (NCT03255876)
- Testing
- Enriched pomegranate juice
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Ketosis, Postprandial Hyperglycemia
Pre-meals of 3-hydroxybutyrate in Type 2 Diabetes
Hyperglycemia following meals in patients with type 2 diabetes mellitus (T2DM) is a common problem. Recently, our group found that oral consumption of the ketone metabolite, 3-hydroxybutyrate (3-OHB), effectively stimulates…
- Conditions
- Ketosis, Postprandial Hyperglycemia, Glucose Metabolism Disorders (Including Diabetes Mellitus)
- Trial name
- PreKetone (NCT05581043)
- Testing
- 3-hydroxybutyrate (3-OHB)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Hyperinsulinemic Hypoglycemia
Evaluating Exenatide for the Treatment of Postprandial Hyperinsulinemic Hypoglycemia
The purpose of the study is to evaluate the effectiveness of exenatide in adults experiencing episodes of hyperinsulinemic hypoglycemia following Roux-en-Y bariatric surgery.
- Trial name
- NCT02685852
- Testing
- Exenatide, Acarbose
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Glycemic Control, Appetite Regulation
The Impact of a Daily Dietary Supplement on Glycemic Control in Individuals With Overweight or Obesity
This clinical trial will evaluate the efficacy of Metabolic Master Pack over a 90-day intervention period. Sixty adults will be randomized to receive either Metabolic Master Pack or placebo.
- Trial name
- NCT07837817
- Testing
- natural glycemic control supplement
- Volunteers
- 60 people
- Sponsor
- University of South Alabama
Healthy
A Comparative Study of Effects of Berry and Grain Products on Postprandial Glycemic Response in Healthy Subjects
This study aims to determine the 2 hour glycemic responses of two bread products and one dried lingonberry product. The average postprandial response of each product is compared with glycemic response after ingestion of control…
- Trial name
- NCT01575509
- Testing
- Berry product, Bread product, Glucose control solution
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Clinical Life Sciences Ltd.
Diabetes Mellitus, Type 2
Post Prandial Glucose (PPG) Study of Empagliflozin in Japanese Patients With Type 2 Diabetes Mellitus
To evaluate the efficacy of empagliflozin administered orally once daily in postprandial glucose and 24-hour glycaemic variability compared to placebo given for 4 weeks as mono-therapy in Japanese patients with type 2 diabetes…
- Trial name
- NCT01947855
- Testing
- Empagliflozin
- Where
- 2 sites in Japan
- Volunteers
- 60 people
- Sponsor
- Boehringer Ingelheim
Glucose Metabolism Disorders
Relative Contribution of Brain Insulin Action for Postprandial Metabolism
The goal of this clinical trial is to clarify (i) the contribution of brain insulin action on regulation of systemic metabolism, (ii) sex-specific differences in the central regulation and (iii) the influence of the menstrual…
- Trial name
- BrainInsPPM (NCT06295640)
- Testing
- Oral glucose tolerance test with double-tracer dilution and intranasal insulin spray
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Healthy, Prediabetic State
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile in Prediabetic and Healthy Subjects
To investigate the effect of two different dosages collagen hydrolysate (CH) on postprandial blood glucose and insulin profile in prediabetic and normo-glycaemic subjects.This will be investigated in a cross-over randomized…
- Trial name
- NCT05887791
- Testing
- Collagen hydrolysate
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Prediabetes, Hyperglycemia
Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study
Sweetch is a personalized mobile-health platform coaching system (mobile phone app) designed to promote adherence to physical activity guidelines for people with prediabetes.
- Conditions
- Prediabetes, Hyperglycemia, Postprandial Hyperglycemia, Impaired Glucose Tolerance
- Trial name
- NCT03315663
- Testing
- Sweetch App & DBWS, Sweetch App Alone
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
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