Clinical trials: Postspinal Hypotension
Adverse Effect
90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of norepinephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151509
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Postspinal Hypotension, Cesarean Delivery
Two Norepinephrine Rescue Bolus Doses for Management of Severe Post-spinal Hypotension During Elective Cesarean Delivery
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population whose incidence reached 60% in many reports.
- Conditions
- Postspinal Hypotension, Cesarean Delivery, Norepinephrine
- Trial name
- NCT05290740
- Testing
- Norepinephrine 5 mcg, Norepinephrine 10 mcg
- Where
- Egypt
- Volunteers
- 158 people
- Sponsor
- Kasr El Aini Hospital
Adverse Effect
Ondansetron for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the effectiveness of ondansetron for postspinal anesthesia hypotension in patients undergoing cesarean section.
- Trial name
- NCT05475873
- Testing
- normal saline, Ondansetron 4 mg, Ondansetron 8 mg
- Where
- China
- Volunteers
- 120 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension During Surgery
IV Dexamethasone in Preventing Post Spinal Hypotension
Orthopedic lower limb procedures are carried out under spinal anesthesia which involves administration of drugs in the space surrounding the spinal cord.
- Trial name
- NCT07052864
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against post-spinal anesthesia hypotension.
- Trial name
- NCT04272567
- Testing
- Norepinephrine, Normal saline
- Where
- China
- Volunteers
- 99 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients
The objective of this study is to investigate the ED90 of norepinephrine and phenylephrine boluses for treating postspinal anesthesia hypotension under intensive treatment in preeclamptic patients during cesarean section
- Trial name
- NCT06158035
- Testing
- Norepinephrine, Phenylephrine
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151522
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) coload infusion dose for postspinal anesthesia hypotension in patients undergoing cesarean section.
- Trial name
- NCT05475886
- Testing
- Hydroxyethyl starch 130/0.4
- Where
- China
- Volunteers
- 40 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Event
Prophylactic Norepinephrine Infusion Combined With Colloid Coloading for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the suitable infusion dose of prophylactic norepinephrine infusion combined with 6% Hydroxyethyl starch (130/0.4) coload for post-spinal anesthesia hypotension in patients undergoing…
- Trial name
- NCT05133817
- Testing
- Normal saline, Norepinephrine (0.025 μg/kg/min), Norepinephrine (0.05 μg/kg/min)
- Where
- China
- Volunteers
- 175 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia.
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556370
- Testing
- Normal saline, Norepinephrine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the suitable infusion dose of phenylephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04576663
- Testing
- Normal saline, Phenylephrine
- Volunteers
- 95 people
- Sponsor
- General Hospital of Ningxia Medical University
Adverse Effect
Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different crystalloid coload volumes on the 90% effective dose of prophylactic norepinephrine infusions for preventing postspinal anesthesia hypotension during cesarean…
- Trial name
- NCT05690334
- Testing
- Crystalloid - 0 ml/kg, Crystalloid - 5 ml/kg, Crystalloid - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Postspinal Hypotension, Pregnant Women Undergoing Cesarean Delivery
Carotid Flow Measurements in Pregnant Women
The goal of this observational study is to reveal the relation between carotid flow changes and post-spinal hypotension in pregnant women between the ages of 20-40.
- Trial name
- NCT06813989
- Testing
- carotid ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital