Clinical trials: Posttraumatic Stress Disorder, completed
Post-Traumatic Stress Disorder
The Role of Computerized Training in Post-Traumatic Stress Disorder
The purpose of this study is to determine whether a computerized training, "Cognitive Bias Modification" targetting appraisals (CBM-App), can reduce dysfunctional appraisals of trauma in patients with Post-Traumatic Stress…
- Trial name
- NCT02687555
- Testing
- Cognitive Bias Modification of Appraisals (CBM-App), Peripheral Vision Task (control condition)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Ruhr University of Bochum
Major Depressive Disorder, Persistent Depressive Disorder
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and anxiety disorders.
- Conditions
- Major Depressive Disorder, Persistent Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder
- Trial name
- TBT-RCT (NCT01947647)
- Testing
- Transdiagnostic Behavior Therapy, Behavioral Activation Therapy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder
The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD)
Oxytocin (OT) - a neurohormone and neuromodulator which is mainly synthesized in the hypothalamus - is a key mediator of complex social and affective behaviors, including emotional empathy.
- Trial name
- NCT01325168
- Testing
- syntocinon nasal spray
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Post-Traumatic Stress Disorder, Sleep Disturbance
Aerobic Exercise Intervention for PTSD Symptoms and Sleep Quality After Earthquake
This randomized controlled trial aims to examine the effects of a moderate-intensity aerobic exercise program on post-traumatic stress disorder (PTSD) symptoms and sleep quality among earthquake survivors living in temporary…
- Trial name
- EX-PTSD (NCT07474259)
- Testing
- Moderate-Intensity Aerobic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Malatya Turgut Ozal University
Posttraumatic Stress Disorder
Study of the Effects of Oxytocin on Attentional Bias and Startle in PTSD
The investigators will test whether intranasal oxytocin (24 IU vs placebo) will induce effects on attention bias and startle comparable to those the investigators have shown to be induced by the presence (vs absence) of a service…
- Trial name
- NCT03211013
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Palo Alto Veterans Institute for Research
Stress Disorders, Post-Traumatic
Evaluation of an Intensive Inpatient Psychotherapy Treatment for Severely and Early Traumatized Children (MOSES)
Evaluation of longitudinal treatment effects applying an intensive psychotherapeutic intervention for inpatients (age of participants: 6-13 years) with a multi-method-approach to address the complex nature of severe childhood…
- Trial name
- MOSES (NCT03894774)
- Testing
- Intensive in-patient psychotherapy treatment, Treatment as usual
- Where
- Germany
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Alcoholism, Anxiety Disorders
Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety
Alcohol use disorders (AUDs) are a major problem facing our society. Their treatment is complex, and involves multiple behavioral and pharmacotherapy interventions.
- Conditions
- Alcoholism, Anxiety Disorders, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00352469
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Creighton University
Combat Disorders, Posttraumatic Stress Disorder
Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
The goals of the proposed research are to produce preliminary evidence of PE with OEF/OIF veterans with PTSD and to examine cognitive, psychophysiological, and neuroendocrine mechanisms of change in PTSD treatment.
- Trial name
- NCT00475241
- Testing
- Prolonged Exposure therapy for PTSD, Present centered therapy for PTSD
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Enhancement of PTSD Treatment With Computerized Executive Function Training
This study focuses on helping Iraq and Afghanistan Veterans with posttraumatic stress disorder (PTSD) benefit fully from therapy by first enhancing their thinking abilities.
- Trial name
- NCT03260127
- Testing
- Computerized executive function training plus CPT (CEFT-CPT), Word game training plus CPT (WT-CPT)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- VA Office of Research and Development
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Posttraumatic Stress Disorder, Depression
The Pitt Center for Emergency Responder Wellness
Emergency responders protect the public despite occupational hazards that threaten their mental health. The Pitt Center for Emergency Responder Wellness will be a clinical innovation hub that: 1) delivers accessible interventions…
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Trial name
- NCT05357586
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Post-Traumatic Stress Disorder
Visual Dysfunction in Mild Traumatic Brain Injury (MTBI): A Comparison Group Study
In an on-going study of visual characteristics of personnel diagnosed with a mild traumatic brain injury (MTBI) related to their service in Iraq and Afghanistan we found a high rate of binocular vision problems (such as…
- Trial name
- VDMTBI (NCT00671450)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder, Anxiety
The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety
The Safe and Sound Protocol (SSP) is a passive acoustic intervention that is designed as a "neural exercise" to promote efficient regulation of autonomic state.
- Trial name
- NCT04999852
- Testing
- Safe and Sound Protocol, Psychotherapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Post Traumatic Stress Disorder, Offensive Aggression
Exploring the Psycho-traumatic Impact of a Violent Act Commited at the Bordeaux-Gradignan Penitentiary Center
The study will seek to explore the possibility of developing post-traumatic stress disorder following a violent offense commited, among the population of prisoners of the Bordeaux-Gradignan penitentiary center.
- Conditions
- Post Traumatic Stress Disorder, Offensive Aggression, Violent Behavior
- Trial name
- IPTAVC (NCT05026450)
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
PTSD
Immunological Changes Through Narrative Treatment of Post-Traumatic Stress Disorder (PTSD) in Torture Victims
Posttraumatic stress disorder (PTSD) is associated with poor health, high health care utilization, and an increased risk for a variety of somatic, inflammatory and autoimmune diseases.
- Trial name
- NCT01206790
- Testing
- NET
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- University of Konstanz
Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD)
NAC for Treating Comorbid PTSD and SUD
As a result of sustained operations in Afghanistan and Iraq, there are an increasing number of U.S. military Veterans with substance use disorders and comorbid posttraumatic stress disorder (PTSD).
- Conditions
- Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
- Trial name
- DoD-NAC (NCT02911285)
- Testing
- N-acetylcysteine, Cognitive behavioral therapy
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder
Using Attentional Bias Modification to Address Trauma Symptoms
Threat-related attentional biases have been identified as a possible precursor to the onset and maintenance of posttraumatic stress disorder (PTSD).
- Trial name
- NCT02615717
- Testing
- Attention Bias Modification
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Post Traumatic Stress Disorder
Web-administered STAIR for Patients on Behavioral Health Waitlists
Posttraumatic stress disorder (PTSD) is a significant public health challenge with population prevalence rates in the US between 6.1 to 9.2%.
- Trial name
- webSTAIR (NCT06431022)
- Testing
- webSTAIR, CHW coaching
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Medical Center
Posttraumatic Stress Disorder
Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault
Interventions are available to all adult women sexual assault survivors to reduce the risk of pregnancy and sexually transmitted infection, yet no interventions are provided to reduce posttraumatic stress.
- Trial name
- NCT04334356
- Testing
- Mobile Web App
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Posttraumatic Stress Disorder, Aggressive Behavior
Treatment of Posttraumatic Stress Disorder and Aggressive Behavior in Soldiers and Ex-combatants
Soldiers deployed in peace-keeping missions as well as ex-combatants in conflict or former conflict regions were and are often exposed to multiple traumatic events and situations in which they are forced to engage in violent…
- Conditions
- Posttraumatic Stress Disorder, Aggressive Behavior, Appetitive Aggression
- Trial name
- NCT02242136
- Testing
- FORNET
- Where
- Burundi
- Volunteers
- 56 people
- Sponsor
- University of Konstanz
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