Clinical trials: Posttraumatic Stress Disorder, completed
Stress Disorders, Post-Traumatic
Treatment of Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children
The purpose of this study is to compare the effectiveness of two psychological therapies used to treat PTSD in children who have recently been sexually abused: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) vs Child…
- Trial name
- NCT00000383
- Testing
- Trauma-Focused CBT, Child-Centered Therapy
- Where
- 3 sites in United States
- Volunteers
- 229 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
HIV Infections, AIDS
The CORE Buprenorphine Project - An HIV Primary Care Program Demonstration
The goal of this study is to develop and evaluate an innovative model of care to better serve patients who are both HIV-infected and opioid-dependent.
- Conditions
- HIV Infections, AIDS, Opiate Dependence, Post-Traumatic Stress Disorders
- Trial name
- BUP (NCT00227357)
- Testing
- On-site - buprenorphine/naloxone (Suboxone), Off-site - methadone or no agonist
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Ruth M. Rothstein CORE Center
Stress Disorders, Post-Traumatic
Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD
The purpose of the current study is to develop a better understanding of the brain mechanisms involved in psychological treatments for posttraumatic stress disorder (PTSD).
- Trial name
- NCT02500719
- Testing
- Computational Model - Real-time Support Vector Machine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Posttraumatic Stress Disorder, Panic Disorder
Study of Brain Circuitry in Anxiety Disorders
A diverse body of research has implicated the amygdalo-cortical circuitry in the pathophysiology of anxiety disorders. For example, one model of PTSD posits exaggerated amygdala responsivity to threat-related stimuli as well as…
- Conditions
- Posttraumatic Stress Disorder, Panic Disorder, Specific Phobias
- Trial name
- NCT01849432
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Post Traumatic Stress Disorder
Enhancing Exposure Therapy for Post Traumatic Stress Disorder (PTSD): Virtual Reality and Imaginal Exposure With a Cognitive Enhancer
The purpose of this study is to test the differences between four active treatment conditions for combat-related Post Traumatic Stress Disorder (PTSD): virtual reality exposure therapy (VRE) or prolonged imaginal exposure therapy…
- Trial name
- NCT01352637
- Testing
- DCS (D-Cycloserine ) + Prolonged Imaginal Exposure, DCS (D-Cycloserine ) + Virtual Reality Exposure
- Where
- 5 sites in United States
- Volunteers
- 192 people
- Sponsor
- Weill Medical College of Cornell University
PTSD, Alcoholism
Integrated Alcohol Disorder and PTSD Treatment
Comorbidity of alcohol use disorder (AD) and posttraumatic stress disorder (PTSD) is common. Currently available treatments often do not lead to sustained recovery from these disorders, possibly because they typically do not…
- Trial name
- NCT01601067
- Testing
- Integrated Prolonged Exposure Therapy, Seeking Safety
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
A Mobile Health Solution for Homework During CBT
The purpose of this study is to preliminarily evaluate a web-based app to improve provider implementation and patient engagement in homework (i.e., between-session practice of skills learned during therapy) during child mental…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04931199
- Testing
- Cognitive Behavioral Therapy (CBT), CBT+App
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of South Florida
PTSD - Post Traumatic Stress Disorder
Psychiatric Nurse-Delivered Eye Movement Desensitization and Reprocessing (EMDR) for Adults With Post-Traumatic Stress Symptoms in Jordan
Here is a plain-language, registry-appropriate Brief Summary you can paste into the form. It is written for patients, families, and healthcare providers: Brief Summary This study examines whether Eye Movement Desensitization and…
- Trial name
- Experimental (NCT07423832)
- Testing
- EMDR
- Where
- Jordan
- Volunteers
- 70 people
- Sponsor
- Al-Quds University
Posttraumatic Stress Disorder (PTSD)
Veterans Individual Placement and Support Towards Advancing Recovery
The primary objective of CSP#589 VIP-STAR is to evaluate the effectiveness of Individual Placement \& Support (IPS) in unemployed Veterans with PTSD.
- Trial name
- VIP-STAR (NCT01817712)
- Testing
- Individual Placement & Support, VA Transitional Work Program
- Where
- 13 sites in United States
- Volunteers
- 541 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Treating Nightmares in Posttraumatic Stress Disorder With Dronabinol
This randomized controlled exploratory phase II trial will test the hypothesis that oral dronabinol improves nightmares (primary outcome) and other PTSD symptoms (secondary outcomes) to a greater extent than placebo over a ten…
- Trial name
- NCT04448808
- Testing
- BX-1
- Where
- 4 sites in Germany
- Volunteers
- 170 people
- Sponsor
- Charite University, Berlin, Germany
Posttraumatic Stress Disorder, Depression
Yoga Breath Program and Client-Centered Exposure for Relief of PTSD in Tsunami Victims
Study hypothesis: that a standardized course of Eastern practices (Breath Water Sound Course -BWS) will significantly relieve PTSD and depression in tsunami victims.
- Trial name
- NCT00290225
- Testing
- Breath Water Sound Course and Traumatic Incident Reduction
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Victim Services Center, Miami
Posttraumatic Stress Disorder (PTSD)
Mindfulness-based Stress Reduction for PTSD in Road Traffic Accident Victims: A Randomized Controlled Trial
The goals of the study are to investigate the effects of mindfulness-based stress reduction (MBSR) on PTSD among road traffic accident victims.
- Trial name
- NCT07521020
- Testing
- mindfulness-based stress reduction
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Universiti Sains Malaysia
Post Traumatic Stress Disorders
Can Service Dogs Improve Activity and Quality of Life in Veterans With PTSD?
Service Dogs are trained to assist people with disabilities to accomplish tasks which permit the individual to be more functional in their home and social environment.
- Trial name
- SDPTSD (NCT02039843)
- Testing
- Emotional Support Dogs, Service Dogs
- Where
- 4 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Adaptive Disclosure: A Combat-Specific PTSD Treatment
The primary objective of this randomized controlled non-inferiority trial is to determine whether or not Adaptive Disclosure (AD), a new combat-specific psychotherapy for Post Traumatic Stress Disorder (PTSD), is as least as…
- Trial name
- NCT01628718
- Testing
- Adaptive Disclosure (AD), Cognitive Processing Therapy, cognitive version only (CPT-C)
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Veterans Medical Research Foundation
Opioid-use Disorder, Mental Health Conditions
The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions
Collaborative care for mental health is increasingly common, but most primary care practices have not embraced similar models for opioid use disorder (OUD).
- Trial name
- NCT04245423
- Testing
- Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists
- Where
- United States
- Volunteers
- 567 people
- Sponsor
- University of Pennsylvania
Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder
EMDR Flash Group Protocol for Earthquake Survivors
This pilot randomized controlled trial evaluated the preliminary effects of the online EMDR Flash Group Protocol among adults affected by the 2023 Kahramanmaraş earthquakes in Türkiye.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder, Anxiety, Depression
- Trial name
- FlashGP-EQ (NCT07672613)
- Testing
- EMDR Flash Group Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Stress Disorders, Post-traumatic
Information Processing Modification in PTSD (Oct. 18)
The purpose of this study is to determine whether a computerized intervention designed to change the nature of attention biases will be effective in reducing the symptoms of post traumatic stress disorder (PTSD) in American…
- Trial name
- NCT00601952
- Testing
- Attention Bias Modification (ABM), Attention Control Condition (ACC)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- San Diego State University
Depressive Symptoms, Substance-related Disorders
Intervention for Veterans With Depression, Substance Disorder, and Trauma
This study will compare two different types of psychotherapy for Veterans with depression, addiction, and a past traumatic experience.
- Conditions
- Depressive Symptoms, Substance-related Disorders, Posttraumatic Stress Disorders
- Trial name
- NCT00958217
- Testing
- Cognitive Processing Therapy-Modified (CPT-M), Integrated Cognitive Behavioral Therapy (ICBT)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- VA Office of Research and Development
Delirium, Stress Disorders, Post-Traumatic
Sedation Influence on Delirium and Post-traumatic Stress-disorder as a Result of Hospitalization in Intensive Care
The aim of this study is to investigate if sedation of Intensive Care Unit (ICU) patients influences the development of delirium during their ICU stay and if incidences of delirium have an impact on the development of…
- Trial name
- NCT01291368
- Where
- 2 sites in Denmark
- Volunteers
- 248 people
- Sponsor
- University of Aarhus
Post-Traumatic Stress Disorder
Visual Dysfunction in Mild Traumatic Brain Injury (MTBI): A Comparison Group Study
In an on-going study of visual characteristics of personnel diagnosed with a mild traumatic brain injury (MTBI) related to their service in Iraq and Afghanistan we found a high rate of binocular vision problems (such as…
- Trial name
- VDMTBI (NCT00671450)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- US Department of Veterans Affairs