Clinical trials: Posttraumatic Stress Disorder, completed
Stress Disorders, Post-Traumatic
Safety and Efficacy of Cognitive Behavior Therapy for People With Post-traumatic Stress and Cardiovascular Illness
This study will evaluate the safety and efficacy of cognitive behavioral therapy in treating people who are experiencing post-traumatic stress disorder after a heart attack.
- Trial name
- NCT00364910
- Testing
- Cognitive behavioral therapy (CBT), Educational session and treatment as usual
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post Traumatic Stress Disorder
Expressing Personal Recollections in English or Spanish to Alleviate Traumatic Emotions (Exprésate)
The purpose of this study is to test if expressive writing about traumatic events has positive changes in women living with post-traumatic stress.
- Trial name
- Exprésate (NCT05090839)
- Testing
- Weekly Emotional Disclosure (WED), Weekly Emotional Disclosure (WED) Spanish
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Adjustment Disorders, Posttraumatic Stress Disorder
The Trauma of Betrayal: Treating Adjustment Disorder With Reconsolidation Blockade Under Propranolol
Attachment injuries are events occurring within couple relationships that involve betrayal or abandonment by a significant other during times of need (e.g., infidelity).
- Conditions
- Adjustment Disorders, Posttraumatic Stress Disorder, Trauma and Stressor Related Disorders
- Trial name
- NCT03151681
- Testing
- Propranolol Pill
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Douglas Mental Health University Institute
Brain Concussion, Posttraumatic Stress Disorder
Brain Injury Outcomes (BIO) Study
Many active duty military, national guard, and reserves personnel who served in the recent conflicts in Afghanistan and Iraq were exposed to blasts and other mechanisms of traumatic brain injury (TBI).1,2 Although physical trauma…
- Conditions
- Brain Concussion, Posttraumatic Stress Disorder, Dementia
- Trial name
- BIO (NCT00724607)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Attentional Bias Retraining in Veterans
The study has two goals. First to develop a computer-based intervention meant to alter cognitive biases that contribute to ongoing PTSD symptoms.
- Trial name
- ABR (NCT02041572)
- Testing
- Attentional bias retraining
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- VA Pacific Islands Health Care System
Posttraumatic Stress Disorder (PTSD)
Effects of an Internet-based Intervention for Posttraumatic Stress Disorder
For several years now, a very successful treatment of posttraumatic stress disorders has been offered in the Netherlands and in Germany. The contact between clients and therapists takes place exclusively via Internet.
- Trial name
- NCT01508377
- Testing
- Exposure for PTSD with cognitive restructuring, Exposure for PTSD without cognitive restructuring
- Where
- Germany
- Volunteers
- 293 people
- Sponsor
- Berlin Center for the Treatment of Torture Victims
Domestic Violence
Strength At Home: Veterans' Program (PTSD-Focused Therapy for Anger and Relationship Conflict Among OEF/OIF Veterans)
This is a research study funded by the Department of Defense to test a therapeutic intervention for male combat veterans who engage in intimate partner violence (IPV).
- Trial name
- NCT01435512
- Testing
- PTSD-Focused CBT for Partner Violence
- Where
- 2 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Posttraumatic Stress Disorder, Depression
Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
The present study is a randomized, controlled trial that compares Behavioral Activation (BA) to Treatment As Usual (TAU) in PTSD Specialty clinics, as early psychotherapeutic interventions for OIF/OEF veterans with posttraumatic…
- Trial name
- NCT00805532
- Testing
- Behavioral Activation treatment, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Major Depressive Disorder
rTMS for PTSD Comorbid With Major Depressive Disorder
The purpose of this study is to see how well a treatment called "Repetitive Transcranial Magnetic Stimulation" works for patients who struggle with symptoms of both posttraumatic stress disorder and major depressive disorder.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Transcranial Magnetic Stimulation, Repetitive
- Trial name
- NCT02273063
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Butler Hospital
Post-Traumatic Stress Disorder
Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these…
- Trial name
- NCT02069366
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Post-traumatic Stress Disorder
Prevention of Post Traumatic Stress Disorder by Early Treatment
To prospectively evaluate the effect of early treatment (cognitive therapy (CT), cognitive-behavioral therapy (CBT) and escitalopram (SSRI) in preventing the occurrence of post-traumatic stress disorder in recent survivors of…
- Trial name
- NCT00146900
- Testing
- Cognitive Behavioral Therapy, Cognitive Therapy, Escitalopram
- Where
- Israel
- Volunteers
- 298 people
- Sponsor
- Hadassah Medical Organization
Post Traumatic Stress Disorder
Studying the Modification of Attention Bias Remotely After Trauma
The investigators will complete an entirely remote randomized controlled trial (RCT) comparing 14 sessions of attention bias modification (ABM), attention control training (ACT), placebo neutral attention training, and a final…
- Trial name
- SMART (NCT04888169)
- Testing
- SMART Mobile App - Attention Bias Modification, SMART Mobile App - Attention Control Training, SMART Mobile App - Control
- Where
- United States
- Volunteers
- 872 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder
Written Exposure Therapy for Posttraumatic Stress Disorder
Although evidence-based treatments for PTSD exist, a significant minority of individuals do not benefit from these treatments and many individuals to not seek treatment, citing barriers such as time commitment and expense of…
- Trial name
- WET (NCT01800773)
- Testing
- Written Exposure Therapy, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Boston University
Post Traumatic Stress Disorder
A Feasibility Study of Internet Delivered Prolonged Exposure
The primary objective with this study is to investigate the feasibility and acceptability of ten weeks of internet delivered prolonged exposure delivered through a digital platform with therapist support.
- Trial name
- NCT05560854
- Testing
- Internet delivered prolonged exposure
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Anxiety, Acute Stress Disorder
Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU)
Infants born premature face numerous medical problems, causing significant anxiety for their parents. Parents experience a range of negative emotions including concern for the health and well being of their fragile infant, guilt…
- Conditions
- Anxiety, Acute Stress Disorder, Posttraumatic Stress Disorder, Depression
- Trial name
- NCT00186472
- Testing
- Brief Cognitive Behavioral Treatment
- Where
- United States
- Sponsor
- Stanford University
Posttraumatic Stress Disorder
Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD
The goal of this observational sub-study is to provide information on how MDMA-assisted therapy affects the brain and body of people with chronic PTSD.
- Trial name
- NCT02102802
- Testing
- Midomafetamine, Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Resilient Pharmaceuticals
Posttraumatic Stress Disorder
Building Resilience After Childhood Emergencies (BRACE)
The investigators study seeks to evaluate the feasibility and efficacy of a parent-focused, early intervention to prevent the development of chronic PTSD for children admitted to the emergency department for an acute traumatic…
- Trial name
- BRACE (NCT02898883)
- Testing
- Building Resilience after Childhood Emergencies (BRACE)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Western Reserve University
Stress Disorders, Post-Traumatic
Acupuncture for the Treatment of Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to evaluate acupuncture as a treatment for Post-Traumatic Stress Disorder (PTSD) and to correlate the diagnosis of PTSD with Traditional Chinese Medicine (TCM) diagnostic patterns.
- Trial name
- NCT00055354
- Testing
- Acupuncture, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Alcohol Abuse, Posttraumatic Stress Disorder
Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder
The purpose of this study is to determine whether the drug prazosin is effective for the treatment of alcohol dependency and symptoms of Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01518972
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Posttraumatic Stress Disorder
Couple HOPES and COVID-19
Posttraumatic Stress Disorder (PTSD) will be a severe problem in Canada in the wake of COVID-19, especially for Military Members, Veterans, First Responders, and Healthcare Workers (MVFH).
- Trial name
- HOPES (NCT04763681)
- Testing
- Couple HOPES Guided, Internet-Delivered, Self-Help Intervention
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- York University