Clinical trials: Posttraumatic Stress Disorder, completed
Stress Disorders, Posttraumatic
Veteran Stress and Learning Study
This is a research study examining the use of two medications, Hydrocortisone and D-Cycloserine, compared to an inactive substance (placebo), on their ability to reduce fear responses and memory of fear in Veterans with symptoms…
- Trial name
- VSL (NCT00674570)
- Testing
- Hydrocortisone, D-Cycloserine
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)
The purpose of the study is to learn how differences in learning under mildly-stressful circumstances may be changed by taking oxytocin. Oxytocin is a hormone made naturally in the body.
- Trial name
- NCT01466127
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder, Opioid-use Disorder
Prolonged Exposure Therapy for PTSD and Opioid Use Disorder
Among patients with opioid use disorder (OUD), 90% report lifetime trauma exposure and 33% meet criteria for posttraumatic stress disorder (PTSD).
- Trial name
- NCT04104022
- Testing
- Prolonged Exposure Therapy, Attendance-based monetary incentives
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Vermont
Chronic Pain, Stress Disorders, Posttraumatic
Compassion Meditation vs. Health Education for Veterans
Chronic pain (CP) is a major health problem for military Veterans, and CP is often associated with comorbid mental health problems, including posttraumatic stress disorder (PTSD) and depression.
- Conditions
- Chronic Pain, Stress Disorders, Posttraumatic, Depression
- Trial name
- NCT04651296
- Testing
- compassion meditation, health education
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
Study of Effectiveness of Mental Health Interventions Among Torture Survivors in Southern Iraq
1. That the psychotherapeutic intervention - Components-Base Interventions (CBI) - is effective in reducing the severity of mental health symptoms experienced by torture survivors in Southern Iraq. 2.
- Conditions
- Depression, Anxiety, Post-Traumatic Stress Disorder
- Trial name
- NCT01177072
- Testing
- Cognitive Processing Therapy, Components-Based Intervention
- Where
- Iraq
- Volunteers
- 342 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Evaluation of Stress Disorders
The purpose of this study is to examine the short-term consequences of trauma and to determine the effectiveness of the drug sertraline in preventing and treating post-traumatic stress disorder (PTSD) and acute stress disorder…
- Trial name
- NCT00050804
- Testing
- sertraline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Post Traumatic Stress Disorder, Major Depression
Prevention of PTSD III: Neurocognitive Training of Emotional Regulation
The proposed work will evaluate the ability of neurocognitive retraining of executive functions and emotional regulation to reduce neurocognitive dysfunctions that follow trauma exposure and thereby prevent PTSD.
- Conditions
- Post Traumatic Stress Disorder, Major Depression, Anxiety Disorders
- Trial name
- NCT02085512
- Testing
- Neurocognitive retraining Web Based Intervention, Control, web-based tasks
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- NYU Langone Health
Posttraumatic Stress Disorder
Use of Electroconvulsive Therapy (ECT) in Chronic, Severe, Treatment Resistant Posttraumatic Stress Disorder
Post Traumatic Stress Disorder is a chronic debilitating illness and few treatment options have demonstrated effectiveness. The study will look at the use of electroconvulsive therapy for the treatment of Post Traumatic Stress…
- Trial name
- NCT00739856
- Testing
- Electroconvulsive Therapy
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Government Medical College Srinagar
Post Traumatic Stress Disorder
Ending Self Stigma for PTSD
Veterans with PTSD report that stigma and fear of stigma have a chilling effect on their participation in mental health treatment.
- Trial name
- ESS-P (NCT02734212)
- Testing
- Ending Self Stigma for PTSD, Enhanced Treatment as Usual
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- VA Office of Research and Development
Depression, Post Traumatic Stress Disorder
NMDA Receptor Modulation for Hyperarousal in PTSD
This Phase 1b study examines the safety and efficacy of parenterally-administered lanicemine in a parallel-arm, randomized, double-blind, placebo-controlled trial in adult patients (N=24) with significant PTSD symptoms and…
- Trial name
- NCT03166501
- Testing
- Lanicemine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor College of Medicine
Post-traumatic Stress Disorder
Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
The purpose of this study is to compare the effectiveness of two cognitive behavioral group psychotherapy interventions in controlling the subjective sleep disturbance in veterans with Post-traumatic Stress Disorder.
- Trial name
- NCT00108628
- Testing
- Imagery Rehearsal, Sleep and Nightmare Management
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
The goal of this clinical trial is to learn if cognitive-behavioral conjoint therapy (CBCT) in combination with MDMA-assisted therapy is safe and effective in people with chronic PTSD and their partners.
- Trial name
- NCT02876172
- Testing
- MDMA, CBCT, Therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Resilient Pharmaceuticals
Post-Traumatic Stress Disorders
Civilian Post-Traumatic Stress Disorder Risperidone Clinical Trial
The purpose of this study is to determine whether the administration of risperidone is effective in the treatment of selective serotonin reuptake inhibitor (SSRI)-resistant post-traumatic stress disorder (PTSD) in civilians.
- Trial name
- NCT00133822
- Testing
- Sertraline and Risperidone
- Where
- 3 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Emory University
Post Traumatic Stress Syndrome
The Effects of D-cycloserine on Stimulus Generalization of Conditioned Fear Healthy Controls.
PROJECT SUMMARY: PTSD is a debilitating psychiatric condition precipitated by exposure to extreme, or life threatening, trauma with an estimated lifetime prevalence between 8% and 9% in U.S. adults.
- Trial name
- DCS (NCT01733030)
- Testing
- Seromycin
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Autism, Trauma
A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults
The goal of this single-group clinical trial is to learn about the initial efficacy and feasibility of telehealth-delivered Written Exposure Therapy (WET) for autistic adults with traumatic stress symptoms.
- Conditions
- Autism, Trauma, Posttraumatic Stress Disorder, Posttraumatic Stress Symptom
- Trial name
- NCT05862467
- Testing
- Written Exposure Therapy (WET) via telehealth
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wyoming
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
PTSD - Post Traumatic Stress Disorder
Neural Basis of the Effect of EMDR Therapy
This study aimed to investigate the effects of a single session of Butterfly Tapping (BT), a self-administered form of alternating bilateral stimulation, on emotional reactivity and its neurophysiological correlates.
- Trial name
- EMDR-NEURO (NCT07550556)
- Testing
- Butterfly Tapping (BT), No intervention control
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Rome Foro Italico
Stress Disorders, Post-Traumatic
Risperidone Treatment for Military Service Related Chronic Post Traumatic Stress Disorder
The purpose of this research of 400 participants is to determine whether a drug called risperidone can decrease symptoms of Post-Traumatic Stress Disorder (PTSD).
- Trial name
- CSP #504 (NCT00099983)
- Testing
- Risperidone
- Where
- 20 sites in United States
- Volunteers
- 296 people
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorders, Unsafe Sex
Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women
Many American Indian (AI) women never receive services for serious mental health problems resulting from traumatic events, violence exposure and maltreatment.
- Conditions
- Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
- Trial name
- NCT01849029
- Testing
- Cognitive Processing Therapy-Cognitive
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Posttraumatic Stress Disorder (PTSD)
Cognitive Processing Therapy for Syrian Patients With PTSD
Background: Studies among Syrian refugees showed high prevalence rates of PTSD. The objective of the present study was to investigate the effectiveness of Cognitive Processing Therapy (CPT) in treating patients with posttraumatic…
- Trial name
- CPT4Syrians (NCT05031728)
- Testing
- Cognitive Processing Therapy (CPT)
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
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