Clinical trials: Posttraumatic Stress Disorder, completed
Posttraumatic Stress Disorder
A Controlled Breathing Course for Social & Emotional Health for Vietnam Veterans With Chronic PTSD-RCT
The main aim of this project is to evaluate the use of a specific Yoga technique of controlled breathing in Vietnam War Veterans with chronic posttraumatic stress disorder.
- Trial name
- NCT00256477
- Testing
- Sudarshan KRIYA Breathing Technique
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
PTSD - Post Traumatic Stress Disorder, Depression/Anxiety
An Integrative, Digital Health Approach to Veteran-Centered PTSD Care
The goal of this study is to test the effectiveness of a stress self-management mobile health system (smartphone app + wearable sensor) alongside an intense physical cycling intervention to reduce symptoms of stress in a veteran…
- Trial name
- NCT06993012
- Testing
- Mobile Health Stress Self Management System, Intensive Cycling Activity
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Psychological Stress, Anxiety
Mindfulness Training in U.S. Army Cohorts
This project aims to contextualize delivery of mindfulness training to U.S. Army personnel, evaluate its effectiveness on measures of executive functions and psychological well-being, and determine best practices for its delivery.
- Conditions
- Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT03310112
- Testing
- 4-week MBAT, 2-week MBAT
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stress Disorders, Post-Traumatic
Development and Validation of a PTSD-Related Functional Impairment Scale
This project has the long-term goal of designing and validating a psychometrically sound inventory of PTSD-related functional impairment for active duty service members and veterans.
- Trial name
- NCT00651872
- Where
- 2 sites in United States
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Intimate Partner Violence (IPV), Anxiety
Effectiveness of Community-based Approach in Reducing the Intimate Partner Violence (IPV) Exposure and Outcome
Abstract Background: There is a little known about the effectiveness of Community-Based Approach (CBA) on reduction of intimate partner violence (IPV) exposure, anxiety, depression and PTSD symptoms as outcomes in collectivist…
- Conditions
- Intimate Partner Violence (IPV), Anxiety, Depression, Post-traumatic Stress Disorder (PTSD)
- Trial name
- NCT06768502
- Testing
- Community Based Approach (CBA)
- Where
- Rwanda
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
Post-Traumatic Stress Disorder
Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)
It is proposed that using Virtual Reality as part of therapy will result in improvements in Post Traumatic Stress Disorder for Service Members with PTSD related to service in Iraq and/or Afghanistan.
- Trial name
- NCT00992953
- Testing
- Treatment as Usual, Virtual Reality Exposure with Stimulus Control
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Office of Naval Research (ONR)
Depression, PostTraumatic Stress Disorder
Study of Effectiveness and Implementation of a Mental Health Intervention With Conflict-affected Communities in Ukraine
This project aims to contribute to the development of a community mental health care system while directly serving the conflict affected population in east Ukraine.
- Trial name
- NCT03058302
- Testing
- CETA (Common Elements Treatment Approach)
- Where
- 3 sites in Ukraine
- Volunteers
- 302 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post-Traumatic Stress Disorder
Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings
A significant number of veterans of the wars in Iraq and Afghanistan are affected by posttraumatic stress disorder (PTSD). The limited reach of effective treatments for PTSD into the veteran population is at least partially due…
- Trial name
- NCT02290639
- Testing
- Brief Cognitive Behavioral Treatment, Minimal Contact
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Posttraumatic Stress Disorder (PTSD)
DElivery of Self Training and Education for Stressful Situations-Primary Care Version
This study will compare a cognitive-behavioral online self-management intervention designed for primary care treatment of war-related PTSD to a control intervention, "optimized usual primary care PTSD treatment".
- Trial name
- DESTRESS-PC (NCT01474057)
- Testing
- DESTRESS-PC, Optimized Usual Primary Care PTSD treatment
- Where
- 4 sites in United States
- Volunteers
- 133 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
PTSD, Addiction
N-acetylcysteine in the Treatment of PTSD and Addiction
Examine the effects of N-acetylcysteine on PTSD symptoms, craving and substance use in veterans with PTSD and comorbid substance use disorders.
- Trial name
- NAC (NCT02499029)
- Testing
- N-acetylcysteine
- Volunteers
- 35 people
- Sponsor
- Medical University of South Carolina
Post Traumatic Stress Disorder
Neurofeedback as a Treatment for Trauma-affected Refugees
Neurofeedback (NF) is a form of treatment that can assist individuals in learning to control their brain wave activity. NF-studies have shown promising results in reducing PSTD-symptoms among military veterans, but there are no…
- Trial name
- NCT05055037
- Testing
- Neurofeedback
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Post-Traumatic Stress Disorder
Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder
To evaluate the safety, tolerability, and response profile of NYX-783 in a Post-Traumatic Stress Disorder population.
- Trial name
- NCT04044664
- Testing
- NYX-783
- Where
- 37 sites in United States
- Volunteers
- 160 people
- Sponsor
- Aptinyx
Emotion Regulation, Cognitive Control
The Effects of Exercise on Emotion Regulation and Cognitive Control in PTSD
The goal of this study is to investigate the effects of a single bout of aerobic exercise on neurophysiological indices of emotion regulation and cognitive control in individuals with clinically significant PTSD symptoms.
- Conditions
- Emotion Regulation, Cognitive Control, PTSD
- Trial name
- NCT05643716
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Post-traumatic Stress Disorder
Psychophysiologic Predictors of Post-deployment Mental Health Outcomes
The primary objectives of this proposal are to develop objective pre-deployment predictors of PTSD and test two pre-deployment resiliency interventions.
- Trial name
- NCT00838006
- Testing
- heart rate variability biofeedback, Cognitive bias modification training
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Biomedical Research Foundation
Posttraumatic Stress Disorder
Hydrocortisone in the Treatment of Intrusions in Patients With Posttraumatic Stress Disorder
To test overall efficacy of hydrocortisone on reexperience of traumatic memories (intrusions) and overall symptomatology in patients meeting criteria of complex chronic PTSD.
- Trial name
- NCT01108146
- Testing
- Arm 1 Hydrocortisone 10 mg, Arm 2 Hydrocortisone 30 mg
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Post Traumatic Stress Disorder, Depression
Treatment of Sleep Disturbances in Trauma-affected Refugees
The overall aim of this study is to examine the effects of sleep enhancing treatment in refugees with PTSD.
- Trial name
- PTF5 (NCT02761161)
- Testing
- Mianserin, Imagery Rehearsal Therapy
- Where
- Denmark
- Volunteers
- 241 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Post-traumatic Stress Disorder
Treatment of PTSD by Reduction of Traumatic Memory Reconsolidation by Propranolol : a Multisite Trial
The purpose of this study is to test whether propranolol, when given during a re-evocation of a traumatic memory, is capable of reducing subsequent PTSD symptoms associated with that memory.
- Trial name
- REDUCTRAUMA2 (NCT01713556)
- Testing
- Propranolol, Trauma reactivation
- Where
- 4 sites in France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Toulouse
Post-Traumatic Stress Disorder
The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants
The purpose of the study is to investigate the effect of treatment of traumatized refugees with a diagnosis of Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT00917397
- Testing
- Sertraline, trauma-focused cognitive behavioural therapy
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Caecilie Buhmann
Posttraumatic Stress Disorder (PTSD)
fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)
To employ a fear learning-extinction paradigm with functional magnetic resonance imaging (fMRI) and skin conductance response (SCR) assessments among patients with posttraumatic stress disorder (PTSD) and trauma exposed healthy…
- Trial name
- NCT01576510
- Testing
- Prolonged Exposure (PE)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Posttraumatic Stress Disorder
Compassion Meditation for PTSD
The goal of this project is to refine an existing compassion meditation protocol for individuals with posttraumatic stress disorder (PTSD), to examine the safety and feasibility of this approach and to collect data to make…
- Trial name
- NCT02372396
- Testing
- Compassion Meditation (CM), Relaxation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Veterans Medical Research Foundation
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