Clinical trials: Posttraumatic Stress Disorder, completed
Posttraumatic Stress Disorder, Anger
Mobile Intervention for Veterans With PTSD and Anger
Anger is the mostly commonly reported reintegration concern among combat Veterans, especially those with PTSD. Problematic anger is associated with significant functional impairment.
- Trial name
- NCT03733028
- Testing
- Mobile Intervention for Reducing Anger (MIRA), Mindfulness Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Opioid Use Disorder
tAN for PTSD and OUD in Buprenorphine Therapy
The goal of this research study supported by the HEAL Initiative (https://heal.nih.gov) is to investigate the effects transcutaneous auricular neurostimulation (tAN), as delivered through the Sparrow Ascent device, on helping…
- Trial name
- NCT06130501
- Testing
- Sparrow Ascent tAN
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Cigarette Smoking, Post Traumatic Stress Disorder
Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster
The purpose of this study was to test the efficacy of a CBT-based smoking cessation treatment enhanced with transdiagnostic skills for the management of anxiety and fear-based avoidance behaviors (CBT-A) relative to a standard…
- Conditions
- Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
- Trial name
- NCT02538601
- Testing
- CBT-A, CBT-S
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stony Brook University
Posttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and CPD
The goal of PROSPER-C is to study effectiveness of ImRs compared to integrated SFT-ImRs in treatment-seeking, adult patients with comorbid PTSD and Cluster C Personality Disorder (CPD).
- Conditions
- Posttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder, Dependent Personality Disorder, Obsessive Compulsive Personality Disorder
- Trial name
- PROSPER-C (NCT03833531)
- Testing
- ImRS, SFT
- Where
- Netherlands
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Arkin
Military Physical and Sexual Trauma, Combat Trauma
Deployment Health in Regular Military Women
The purpose of this study is to determine potential risk factors for physical and sexual assault in regular military women (as opposed to Reserve and National Guard).
- Conditions
- Military Physical and Sexual Trauma, Combat Trauma, PTSD, TBI
- Trial name
- DHRMS (NCT01692067)
- Where
- 2 sites in United States
- Volunteers
- 871 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Post Traumatic Stress Disorder
Hyperbaric Oxygen Therapy for Post Traumatic Stress Disorder
The study evaluates the effect of hyperbaric oxygen therapy on veterans with combat-associated PTSD in an double blind sham control study.
- Trial name
- HBOT (NCT04518007)
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 56 people
- Sponsor
- Assaf-Harofeh Medical Center
Posttraumatic Stress Disorder, Reintegration
Evaluation of ProVetus/Sponsorship Initiative
Some Veterans who recently served in the military report significant psychological problems based on their experiences in the military.
- Conditions
- Posttraumatic Stress Disorder, Reintegration, Social Support
- Trial name
- NCT02627612
- Testing
- Pro Vetus, Team Red, White, and Blue (TM RWB)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Borderline Personality Disorder, PTSD
Neural Correlates of Stress Hormones
To investigate which neuronal correlates underlie cortisol-induced enhancement of memory retrieval in PTSD and BPD.
- Trial name
- Cort-fMRI (NCT02523664)
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Post-Traumatic Stress Disorder in Children, Post-Traumatic Stress Disorder in Adolescence
Video NET With CYP Who Witnessed Domestic Violence
Research suggests that children and young people (CYP) who witness domestic violence are susceptible to develop Post-traumatic stress (PTS).
- Conditions
- Post-Traumatic Stress Disorder in Children, Post-Traumatic Stress Disorder in Adolescence, Post-Traumatic Stress Disorder Complex, Domestic Violence
- Trial name
- NCT04866511
- Testing
- Narrative Exposure Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Nottingham
Post Traumatic Stress Disorder, Depression
Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive
The purpose of the study is to investigate whether an occupational therapy program could enhance mental health outcomes for veterans who SCUBA dive.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Stress, Psychological
- Trial name
- NCT03928392
- Testing
- SCUBA with Occupational Therapy (OT), Self-Contained Underwater Breathing Apparatus (SCUBA) without OT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Loma Linda University
Posttraumatic Stress Disorder
Treating Nightmares in Posttraumatic Stress Disorder With Dronabinol
This randomized controlled exploratory phase II trial will test the hypothesis that oral dronabinol improves nightmares (primary outcome) and other PTSD symptoms (secondary outcomes) to a greater extent than placebo over a ten…
- Trial name
- NCT04448808
- Testing
- BX-1
- Where
- 4 sites in Germany
- Volunteers
- 170 people
- Sponsor
- Charite University, Berlin, Germany
Major Depressive Disorder, Dysthymic Disorder
Quetiapine in Co-Morbid Depressive and Anxiety Disorders
This multi-centred study will be conducted at three centres. The design will be a randomized, placebo-controlled, parallel-group one.
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- NCT00688818
- Testing
- Quetiapine
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Centre for Addiction and Mental Health
Hearing Impairment, Hearing Aid Fitting
Blast Exposed Veterans With Auditory Complaints
The purpose of this study is to study blast-exposed Veterans who report hearing handicap but show normal or near normal results on standard audiometric testing.
- Trial name
- NCT02122458
- Testing
- mild-gain hearing aids with high-frequency emphasis over 6-months
- Where
- 3 sites in United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
A Pilot Study Of Riluzole In Patients With Post Traumatic Stress Disorder (PTSD)
This open label study will evaluate the safety and efficacy of riluzole in patients with PTSD. Patients will receive riluzole 50mg twice per day orally for 12 weeks as outpatient, with a one month follow up at week 16.
- Trial name
- NCT02019940
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Posttraumatic Stress Disorders, Depression
Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder
The objective of the proposed study is to conduct a systematic comparison of post traumatic stress disorder (PTSD) outcomes for veterans receiving exposure therapy via telemedicine versus in-person care.
- Conditions
- Posttraumatic Stress Disorders, Depression, Anxiety
- Trial name
- NCT01158001
- Testing
- Prolonged exposure therapy
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Veterans Medical Research Foundation
Posttraumatic Stress Disorder
Couple HOPES and COVID-19
Posttraumatic Stress Disorder (PTSD) will be a severe problem in Canada in the wake of COVID-19, especially for Military Members, Veterans, First Responders, and Healthcare Workers (MVFH).
- Trial name
- HOPES (NCT04763681)
- Testing
- Couple HOPES Guided, Internet-Delivered, Self-Help Intervention
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- York University
Stress Disorders, Post-Traumatic, Schizophrenia
Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Individuals With Severe Mental Illness
This study will develop a cognitive behavioral therapy (CBT) program to treat symptoms of post-traumatic stress disorder (PTSD) in people with severe mental illnesses who are treated within community mental health systems.
- Trial name
- NCT00078741
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
PTSD
Safety Study of Riluzole to Treat Post-traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether Riluzole is effective in the augmentation treatment of post-traumatic stress disorder (PTSD) that is experienced by Active Duty military service members and Operation Enduring…
- Trial name
- NCT02155829
- Testing
- Riluzole
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Uniformed Services University of the Health Sciences
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