Clinical trials: Posttraumatic Stress Symptom
Posttraumatic Stress Disorder, Depression
Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD)
Objectives: The primary objective is to test whether right prefrontal cortex low frequency 1 Hz rTMS versus right prefrontal high frequency 10 Hz rTMS provides a significantly greater improvement in function as measured by IPF…
- Trial name
- NCT02158663
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- James A. Haley Veterans Administration Hospital
Stress Disorders
Effects of an Alternative Treatment for Military Sexual Trauma on PTSD Symptoms, Neurosteroids and Brain Function
Our specific aims are: 1. To examine the efficacy of GIFT in improving MST-related clinical outcomes in women veterans 2. To examine the effects of GIFT on fronto-limbic brain function and 3.
- Trial name
- NCT00374738
- Testing
- Guided Imagery for Trauma (GIFT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Samueli Institute for Information Biology
Depression, Grief
Iwankapiya-Healing: Historical Trauma Practice and Group IPT for American Indians
This study will pilot an intervention that combines group Interpersonal Psychotherapy (IPT), an empirically-supported treatment, and the Historical Trauma and Unresolved Grief Intervention (HTUG), a Tribal Best Practice for…
- Conditions
- Depression, Grief, PTSD, Interpersonal Relations
- Trial name
- HTUG-IPT (NCT02124694)
- Testing
- HTUG
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
Anxiety, Depression
Quality of Dying in the Intensive Care Unit: Validation of the CAESAR Scale
The purpose of the study is to evaluate the quality of the dying process in french ICUs (assessed by the CAESAR scale) and to compare physicians', nurses' and relatives perceptions and experiences, with a one-year follow-up of…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- CAESAR (NCT01549197)
- Where
- 47 sites in France
- Volunteers
- 475 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Posttraumatic Stress Disorder
CIH Stepped Care for Co-occurring Chronic Pain and PTSD
The goal of this clinical trial is to evaluate the feasibility, acceptability, appropriateness, and retention of patient participants of a CIH Stepped Care approach for co-occurring chronic pain and PTSD vs.
- Trial name
- NCT06219408
- Testing
- CIH Stepped Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Alcohol Abuse, Posttraumatic Stress Disorder
Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder
The purpose of this study is to determine whether the drug prazosin is effective for the treatment of alcohol dependency and symptoms of Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01518972
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Posttraumatic Stress Disorder, Aggressive Behaviour
Reintegrating Children Living at Landfills in Burundi Into Society by Means of a Comprehensive Family Program Addressing Maltreatment and Mental Health Symptoms
Children living at the landfills of Bujumbura are often exposed to maltreatment, including emotional neglect and physical abuse, and traumatic experiences. Furthermore, they grow up in severe poverty.
- Conditions
- Posttraumatic Stress Disorder, Aggressive Behaviour, Parental Maltreatment, Days Spent at the Landfill
- Trial name
- NCT03846154
- Testing
- Comprehensive family intervention including individual sessions of FORNET
- Where
- Burundi
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Post Traumatic Stress Disorder
Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder
The overarching objective of the proposed project is to test the clinical efficacy of CBD in the treatment of post-traumatic stress disorder using a rigorous double-blind randomized clinical trial methodology.
- Trial name
- NCT04197102
- Testing
- CBD Isolate, CBD Broad Spectrum
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Texas at Austin
Suicide, Posttraumatic Stress Disorder
Decreasing Suicide Risk Among Service Members With Posttraumatic Stress
In this study, the investigators will conduct a randomized controlled trial (RCT) to evaluate the efficacy of the WET-S + treatment as usual (TAU) compared with TAU among high-risk, suicidal service members with PTSD or…
- Trial name
- NCT04225130
- Testing
- Written Exposure Therapy -for Suicide, Treatment as Usual
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Boston VA Research Institute, Inc.
Posttraumatic Stress Disorder, Aggressive Behavior
Adressing PTSD Symptoms and Aggressive Behavior in Vulnerable Children in Burundi
Children either living in the streets of Bujumbara or that are similarly affected by extreme poverty or violence are regularly exposed to traumatic events.
- Trial name
- NCT03498482
- Testing
- Narrative Exposure Therapy for Forensic Offender Rehabilitation (FORNET)
- Where
- Burundi
- Volunteers
- 19 people
- Sponsor
- University of Konstanz
Posttraumatic Stress Disorder, Major Depressive Disorder
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel
Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05530642
- Testing
- Emotional Resilience Skills Training (ERST)
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Regina
Complicated Grief, Prolonged Grief Disorder
Pilot Study of Behavioral Activation for Prolonged Grief
The Institute of Medicine identifies Prolonged Grief (PG) as a critical under-addressed public health problem for which are no empirically supported treatments.
- Conditions
- Complicated Grief, Prolonged Grief Disorder, Major Depressive Disorder, Posttraumatic Stress Disorder
- Trial name
- NCT01556048
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Anthony Papa
Low Back Pain, Posttraumatic Stress Disorder
Low Back Pain and Comorbid Posttraumatic Stress Disorder
The aim is to test whether the psychotherapeutic intervention Somatic Experiencing targeting Post Traumatic Stress Disorder (PTSD) symptoms will have an additional positive effect on the outcomes of guided physiotherapy against…
- Trial name
- NCT03244046
- Testing
- Psychotherapy, Physiotherapy
- Volunteers
- 140 people
- Sponsor
- University of Southern Denmark
Intimate Partner Violence, Depression
MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence (MOSAIC Plus) Open Trial
The purpose of this R34 exploratory research proposal is to conduct formative work for a larger randomized controlled trial (RCT) evaluating the effectiveness of the "Mother AdvocateS In the Community (MOSAIC) Plus" intervention…
- Conditions
- Intimate Partner Violence, Depression, Posttraumatic Stress Symptom
- Trial name
- MOSAIC Plus OT (NCT05968534)
- Testing
- MOSAIC Plus
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Michigan State University
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Posttraumatic Stress Disorder, Stress
An Early Intervention to Increase Maternal Self-efficacy After Preterm Birth
This study aims to investigate the effects of an early intervention (joint observation and video feedback) on maternal parenting self-efficacy following a premature birth.
- Conditions
- Posttraumatic Stress Disorder, Stress, Anxiety, Depression
- Trial name
- JOIN (NCT02736136)
- Testing
- joint observation and video feedback
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Traumatic Brain Injury, Insomnia
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and…
- Conditions
- Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress
- Trial name
- NCT05663034
- Testing
- Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Posttraumatic Stress Disorder
Testing the Efficacy of an Eye-tracking-based Treatment in Reducing Stress-related Symptoms in Veterans With PTSD
The study will examine the efficacy of a feedback-based treatment applying eye-tracking (Gaze-Contingent Music Reward Therapy) to change attention and gaze patterns associated with angry faces relative to a response-time-based…
- Trial name
- NCT05243459
- Testing
- Gaze-Contingent Feedback Training, Attention Bias Modification, Non-Contingent Feedback Training
- Where
- Israel
- Volunteers
- 121 people
- Sponsor
- Tel Aviv University