Clinical trials: Posttraumatic Stress Symptoms
Stress Disorders, Post-Traumatic, Combat Disorders
Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether prazosin will: reduce the incidence of nightmares and sleep disturbance increase functioning and sense of well being in combat-trauma exposed Operation Iraqi Freedom/Operation…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Sleep Disorders
- Trial name
- NCT00990106
- Testing
- prazosin hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
PTSD, Depression
Vilazodone for the Treatment of Posttraumatic Stress Disorder
The purpose of this study is to determine whether vilazodone is effective in the treatmen of Posttraumatic Stress Disorder (PTSD)and co-morbid mild or more depression.
- Trial name
- NCT01715519
- Testing
- Treatment (Viibryd)
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Southern California Institute for Research and Education
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Posttraumatic Stress Disorder, Depression
Randomized Controlled Trial of the Effectiveness of Group Treatment With War-Exposed Bosnian Adolescents
Context: This is the first multi-site randomized controlled study of the effectiveness of a group treatment for war-exposed adolescents delivered in-country within a public school system.
- Conditions
- Posttraumatic Stress Disorder, Depression, Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT00480480
- Testing
- Trauma and Grief Component Therapy for Adolescents (Group Version)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Posttraumatic Stress Disorder (PTSD)
Trajectories of Psychopathology in Response to NET
Narrative Exposure Therapy (NET) has been proven to be effective in the treatment of Posttraumatic Stress Disorder (PTSD) and trauma-related depression in more than a dozen controlled clinical trials.
- Trial name
- TOP-NET (NCT02852616)
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Post-Traumatic Headache, PTSD
Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms
Service members and/or recently separated veterans with post traumatic stress symptoms and mild traumatic brain injury may participate in 8 sessions including 2 sessions including interviews and questionnaires as well as 6…
- Conditions
- Post-Traumatic Headache, PTSD, TBI, TBI (Traumatic Brain Injury)
- Trial name
- ArtTherapy (NCT04776304)
- Testing
- Art Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Walter Reed National Military Medical Center
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Depression
Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD)
Objectives: The primary objective is to test whether right prefrontal cortex low frequency 1 Hz rTMS versus right prefrontal high frequency 10 Hz rTMS provides a significantly greater improvement in function as measured by IPF…
- Trial name
- NCT02158663
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- James A. Haley Veterans Administration Hospital
PostTraumatic Stress Disorder, Traumatic Brain Injury
Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder
The purpose of this study is to evaluate the safety and efficacy of individualized, Biometrics-guided Magnetic e-Resonance Therapy (MeRT) treatment of Post-Traumatic Stress Disorder
- Conditions
- PostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive Symptoms
- Trial name
- MeRT-005-B (NCT02990793)
- Testing
- Active MeRT Treatment
- Where
- 8 sites in United States
- Volunteers
- 158 people
- Sponsor
- Wave Neuroscience
Post-Traumatic Stress Disorder
Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings
A significant number of veterans of the wars in Iraq and Afghanistan are affected by posttraumatic stress disorder (PTSD). The limited reach of effective treatments for PTSD into the veteran population is at least partially due…
- Trial name
- NCT02290639
- Testing
- Brief Cognitive Behavioral Treatment, Minimal Contact
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Posttraumatic Stress Disorder
Treatment Effects of Narrative Exposure Therapy
This study compares Narrative Exposure Therapy with a Waiting list control group, both consists of traumatized patients with diagnosed Posttraumatic Stress Disorder.
- Trial name
- NCT00660439
- Testing
- Narrative Exposure Therapy
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- University of Bergen
Posttraumatic Stress Disorder, Aggressive Behavior
Treatment of Posttraumatic Stress Disorder and Aggressive Behavior in Soldiers and Ex-combatants
Soldiers deployed in peace-keeping missions as well as ex-combatants in conflict or former conflict regions were and are often exposed to multiple traumatic events and situations in which they are forced to engage in violent…
- Conditions
- Posttraumatic Stress Disorder, Aggressive Behavior, Appetitive Aggression
- Trial name
- NCT02242136
- Testing
- FORNET
- Where
- Burundi
- Volunteers
- 56 people
- Sponsor
- University of Konstanz
PostTraumatic Stress Disorder, Eating Disorder
Integrated Treatment for Co-occurring Eating Disorders and Posttraumatic Stress Disorder
Although psychotherapy for eating disorders (EDs) can be effective, approximately 50% of those who complete a course of the best available therapy continue to have significant ED symptoms at the end of treatment.
- Trial name
- NCT03502564
- Testing
- CBT for ED, Concurrent CBT for ED and PTSD
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University Health Network, Toronto
Posttraumatic Stress Disorder, Traumatic Brain Injury
Cognitive REmediation After Trauma Exposure Trial = CREATE Trial
This study will evaluate the efficacy of methylphenidate and galantamine in the treatment of persistent cognitive symptoms associated with posttraumatic stress disorder (PTSD) and/or traumatic brain injury (TBI).
- Trial name
- CREATE (NCT01416948)
- Testing
- Methylphenidate Hydrochloride 20 mg, Galantamine 12 mg
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico
Posttraumatic Stress Disorder, Depression
Clinical Trial of Interpersonal Therapy for Survivors of the Sichuan Earthquake
The enormous global burden of mental illness has been estimated through the publication of the Global Burden of Disease Study. Research confirms that populations exposed to mass trauma such as natural disaster bear a particularly…
- Trial name
- NCT01624935
- Testing
- interpersonal psychotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
PostTraumatic Stress Disorder, Sleep Disorder
Remote Study of NightWare for PTSD With Nightmares
This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress…
- Conditions
- PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders
- Trial name
- NWVRCT (NCT03934658)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- NightWare
Posttraumatic Stress Disorder
Aripiprazole in the Treatment of Post-Traumatic Stress Disorder Symptoms
32 outpatients with a Posttraumatic Stress Disorder were included in a randomized comparative single-blind study to study the efficacy of aripiprazole to treat post-traumatic stress symptoms.
- Trial name
- AripipPTSD (NCT00440713)
- Testing
- Aripiprazole, Interpersonal Therapy
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo