Clinical trials: Poverty, open to volunteers
Preterm Birth
Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm
Young adults born very preterm (32 weeks gestation or earlier) do not respond well to aerobic exercise training, meeting the recommendations set by the Physical Activity Guidelines for Americans, where they do not increase their…
- Trial name
- NCT06334107
- Testing
- Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Aging, Athletic Injuries
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability.
- Conditions
- Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
- Trial name
- NCT05344001
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marquette University
Cardiac Surgery Associated - Acute Kidney Injury, Critical Illness
Prognostic Value of Metabolic Characteristics in High-Risk Populations for Acute Kidney Injury After Cardiac Surgery
This project aims to explore the metabolic characteristics of adverse renal outcomes in high-risk populations after cardiac surgery by using multi-omics techniques, in order to understand the metabolic changes in patients during…
- Trial name
- NCT07521787
- Testing
- Standard care "bundle"
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Shanghai Zhongshan Hospital
Stroke, Poor Quality Sleep
Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise
health problems, such as heart disease, diabetes, cognitive impairment, and dementia. After a person suffers a stroke, they often experience difficulties in getting a good night's sleep.
- Trial name
- NCT06847074
- Testing
- Multimodal Exercise, Cognitve and Social Activities
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- University of British Columbia
Heat Stress
Heat Stress Exposure Among Low-Income Residents in Bangladesh and Evaluation of Indoor Interventions
The goal of this clinical trial is to learn if infrastructure and equipment installed to cool homes reduce adverse health outcomes.
- Trial name
- NCT06979258
- Testing
- Cooling intervention
- Where
- Bangladesh
- Volunteers
- 1,539 people
- Sponsor
- University of California, Berkeley
Germ Cell Tumor
Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours
The purpose of this study is to determine whether accelerated BEP chemotherapy is more effective than standard BEP chemotherapy in males with intermediate and poor-risk metastatic germ cell tumours.
- Trial name
- P3BEP (NCT02582697)
- Testing
- Bleomycin (active name: Bleomycin Sulfate), Etoposide, Cisplatin
- Where
- 56 sites in United States, Australia and 2 more
- Volunteers
- 500 people
- Sponsor
- University of Sydney
Bariatric Surgery Candidate, Obesity, Morbid
The Poor Responders Study
Obesity and type 2 diabetes are major causes of illness and premature death worldwide and their incidence is increasing rapidly. Bariatric surgery is considered as the "gold-standard" surgical treatment for both conditions.
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Diabetes Mellitus, Type 2
- Trial name
- NCT05404061
- Testing
- Gut hormones
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- Imperial College London
Infertility, Infertility (IVF Patients)
Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization
The goal of this study is to evaluate the role of Somatropin and Dehydroepiandrosterone (DHEA) on ovarian reserve parameters and intracytoplasmic sperm injection (ICSI) outcome in poor ovarian responder.
- Trial name
- NCT07323329
- Testing
- Somatropin (4IU for 1 month) plus, folic acid 400 mcg per day., DHEA plus folic acid 400mcg per day, control group
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Beni-Suef University
Psychopathology, Child Mental Health
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it…
- Conditions
- Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders
- Trial name
- NCT07641244
- Testing
- Psychological fMRI task
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Northwestern University
Acetabular Labrum Tear, Femoro Acetabular Impingement
Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies
The goal of this clinical trial is to assess the effect of PRP/PPP/BMAC application on functional outcomes after hip arthroscopy to address acetabular labral pathologies. The main questions it aims to answer are: 1.
- Conditions
- Acetabular Labrum Tear, Femoro Acetabular Impingement, Chondral Defect, Bone Marrow Aspirate Concentrate
- Trial name
- PRP; PPP; BMAC (NCT06003101)
- Testing
- Bone marrow aspirate concentrate (BMAC), Control
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Type 2, Nutrition Poor
Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)
This is a pragmatic randomized controlled trial (pRCT) that aims to test the effect of produce provision, diabetes education, and community referrals on hemoglobin A1c levels in individuals with type 2 diabetes experiencing food…
- Conditions
- Diabetes Mellitus, Type 2, Nutrition Poor, Food Deprivation
- Trial name
- NCT05472441
- Testing
- Mid-Ohio Food Farmacy, Mid-Ohio Food Farmacy + Cooking for Diabetes, Mid-Ohio Food Farmacy + Health Impact Ohio Pathways Hub
- Where
- United States
- Volunteers
- 568 people
- Sponsor
- Ohio State University
Poor Quality Sleep
SHLH for Urban Adolescents (Efficacy Trial)
The overall study goal is to test the efficacy and cost-effectiveness of Sleeping Healthy, Living Healthy (SHLH), a novel intervention that combines healthy sleep practices with mind-body integrative health (MBIH) approaches to…
- Trial name
- NCT07893015
- Testing
- Sleeping Healthy, Living Healthy, Sleep for Teens
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Columbia University
Depression, Physical Inactivity
Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2)
This study develops and tests a dynamic workplace-based depression intervention that is tailored to the specific social and behavioral needs of low-wage hospital service workers.
- Trial name
- NCT06753123
- Testing
- A workplace-based depression intervention for low-wage hospital workers
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- San Diego State University
Major Depressive Disorder, Dysthymic Disorder
Testing a Precision Psychotherapy System for Low-income Patients
The purpose of this study is to evaluate the feasibility of an evidence-based system to recommend core interventions, before the beginning of treatment, to psychotherapists treating low-income patients with depressive or anxiety…
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Specific Phobia, Social Anxiety Disorder
- Trial name
- ML_LMIC (NCT05118594)
- Testing
- Pre-treatment psychotherapy recommendations
- Volunteers
- 111 people
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Poor Ovarian Response, Ovarian Reactivation
Proteomic and Biological Characterisation of Plasma for the Study of Changes Following Ovarian Reactivation Treatment
The samples used in PRGF treatments owe their effectiveness to the handling, concentration, and preservation of their components, which explains why samples obtained with different platelet-rich plasma preparation systems may…
- Trial name
- NCT07376460
- Testing
- Platelet Rich Plasma + BMDSCs mobilization
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Lung Cancer (NSCLC)
Real-world Experience With Combination Chemotherapy and Osimertinib in Poor Prognostic Group of Metastatic EGFR-mutated Lung Adenocarcinoma
The aims of this study are to determine the potential clinical benefits (in terms of PFS, objective response and OS) of add-on systemic chemotherapy (pemetrexed+carboplatin/cisplatin) to first-line osimertinib treatment among the…
- Trial name
- NCT06918782
- Testing
- Osimertinib plus platinum doublet chemotherapy
- Volunteers
- 47 people
- Sponsor
- The University of Hong Kong
HCC - Hepatocellular Carcinoma
Social Determinants of Health HCC Trial
The goal of this study is to test whether providing various social resources (transportation support through Lyft rides, housing support through Hyatt House LA, and meal support through Project Angel Food LA) will reduce…
- Trial name
- NCT07568457
- Testing
- Social Determinants of Health Program, Patient Navigation
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Southern California
Mental Health
Study of Mental Health and Relationships
The goal of this clinical trial is to test effects of the Great Life Mentoring (GLM) program on the mental health and adaptive functioning on school-age youth (ages 9-16) from low-income families who are receiving outpatient…
- Trial name
- SMART (NCT06534827)
- Testing
- Great Life Mentoring
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology
Impact of Day 2 Versus Day 3 Fresh Embryo Transfer on Live Birth Rate in Poor-Prognosis Patients
This study aimed to compare the efficacy (live birth rate) of fresh embryo transfer on Day 2 versus Day 3 in POSEIDON Group 4 patients, and to determine the optimal timing of embryo transfer for this population.
- Conditions
- POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology, Female Infertility Due to Diminished Ovarian Reserve
- Trial name
- NCT07533695
- Testing
- Day 2 Fresh Embryo Transfer
- Volunteers
- 470 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Cancer
Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies
This is a substudy (Part 2) of a larger two-part clinical trial including both observational and therapeutic (interventional) cohorts to assess the progression free survival ratio of patients treated with a targeted therapy based…
- Trial name
- NCT03089554
- Testing
- Therapeutic Intervention
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Rachel Miller