Clinical trials: PrEP
Healthy
Feasibility Study to Evaluate the Performance of Flocculation-Adsorption System for Colon Cleansing Enhancement
The purpose of this study is to demonstrate feasibility of enhancing colon cleansing.
- Trial name
- RD-400 (NCT01370759)
- Testing
- Cleaning capsule
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Bacterial Recovery of Skin Flora Post-Product Application
In Vivo Patient Preoperative Skin Prep Persistence
The objective of the study is to demonstrate persistence of the CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT02447497
- Testing
- 3M CHG/IPA Surgical Skin Preparation - Abdominal Region, Normal Saline - Abdominal Region, 3M CHG/IPA Surgical Skin Preparation - Inguinal Region
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Colonoscopy
Clinical Evaluation of a New Reduced Volume Bowel Preparation
Monocentric, cleansing evaluation pilot study in patients undergoing colonoscopy.
- Trial name
- NCT00321230
- Testing
- macrogol3350 NA sulphate NACL KCL ascorbic acid NA ascorbate
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Norgine
Embolization, Vascular Tumor
Evaluation of a Simple-Prep Controlled Embolic
The objective of this study is to evaluate the safety and effectiveness of the GPX® Embolic Device when used as indicated for embolization requiring distal vessel penetration in 114 subjects in up to 25 investigational sites in…
- Conditions
- Embolization, Vascular Tumor, Renal Angiomyolipoma, Renal Cell Carcinoma
- Trial name
- GPX (NCT06453642)
- Testing
- GPX® Embolic Device
- Where
- 20 sites in United States, Canada and 1 more
- Volunteers
- 114 people
- Sponsor
- Fluidx Medical Technology, Inc.
Colonoscopy
A Safety and Efficacy Comparison of BLI4700 Bowel Prep Versus an FDA-approved Comparator in Adults Prior to Colonoscopy
The objective of this study is to compare the safety and efficacy of BLI4700 bowel preparation to an FDA-approved bowel preparation as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT03404401
- Testing
- BLI4700, Polyethylene glycol bowel preparation
- Where
- 23 sites in United States
- Volunteers
- 620 people
- Sponsor
- Braintree Laboratories
Pre-Exposure Prophylaxis of HIV Infection
Study of Lenacapavir Taken Twice a Year for HIV Pre-Exposure Prophylaxis (PrEP)
The goals of this clinical study are to learn more about the study drug lenacapavir (LEN), by comparing the consistent and continuous use of LEN and emtricitabine/tenofovir disoproxil fumarate (coformulated; Truvada®) (F/TDF)…
- Trial name
- PURPOSE 5 (NCT06513312)
- Testing
- Lenacapavir Injection, Lenacapavir Tablet, Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
- Where
- 14 sites in France, United Kingdom
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Colonoscopy
HyGIeaCare Prep vs Split-dose PEG Prep Prior to Colonoscopy
The purpose of this study is to compare the level of cleanliness using the HyGIeaCare Prep vs the standard of care Split-dose PEG prep used prior to colonoscopy.
- Trial name
- NCT02893748
- Testing
- HyGIeaCare Prep, Colonoscopy, polyethylene glycol (PEG)
- Volunteers
- healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Bowel Preparation Before Colonoscopy
A Study of the Efficacy and Safety of Bowklean and Klean-Prep With Dulcolax for the Bowel Preparation Prior Colonoscopy
The primary objective of this study is to demonstrate that investigation medication (Bowklean) is not less effective than the active comparator (Klean-Prep with Dulcolax), with regards to the overall quality of bowel preparation…
- Trial name
- NCT01984008
- Testing
- Picosulfate sodium, magnesium oxide, citric acid
- Where
- Taiwan
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Virus Diseases, Rabies
A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.
The aim of this study is to evaluate the long-term (up to approx.10 years) persistence and to assess the boostability of immune responses in participants who received a primary series of accelerated or conventional rabies PrEP IM…
- Trial name
- NCT02545517
- Testing
- Rabipur, Blood sampling, Purified Chick-Embryo Cell Rabies Vaccine
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infection
A Prospective, Observational Study of Pregnancy Outcomes Among Women Exposed to Truvada for PrEP Indication
This is a prospective, observational study to describe pregnancy outcomes among HIV-1 uninfected pregnant women who are taking emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) (Truvada®) for a pre-exposure prophylaxis…
- Trial name
- NCT01865786
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Gilead Sciences
Bowel Preparation
Safety and Tolerability Study of an Edible Colon Preparation
The purpose of this study is to learn about a new bowel preparation that uses food to clean the colon. In order to learn about this new food preparation, some people in this study will get the food preparation, and others will…
- Trial name
- NCT02402270
- Testing
- NuLYTELY® (PEG 3350), ECP-019, MoviPrep® (PEG 3350)
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- ColonaryConcepts LLC
Screening Colonoscopy
Use of a Colon Irrigation Device as a Preparation for a Colon Visualization Procedure
A prospective, single center, study to evaluate the effectiveness of the HyGIeaCare Prep when used in combination with the PillCam COLON; the hypothesis is that the HyGIeaCare Prep will be easier for the patients to tolerate, and…
- Trial name
- NCT03458390
- Testing
- HyGIeaCare colon irrigation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Bacterial Reduction on Skin Flora Post-product Application
In-vivo Efficacy Study of Patient Pre-operative Preps
The purpose of this study is to determine the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT01968707
- Testing
- ChloraPrep Hi-Lite Orange, Normal saline, 3M CHG/IPA Prep Tint 10.5-mL
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Rabies
RNActive® Rabies Vaccine (CV7201) in Healthy Adults
The purpose of this trial is to assess the safety and immunogenicity of an investigational RNActive® rabies vaccine (CV7201) in healthy adults.
- Trial name
- NCT02241135
- Testing
- CV7201 mRNA
- Where
- Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- CureVac
Surgical Skin Preparation, Surgical Procedure, Unspecified
In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area
This study evaluates reduction of resident flora produced by the test product within a defined prepped area of skin.
- Trial name
- NCT03681990
- Testing
- 3M CHG/IPA Prep
- Where
- Romania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Colonoscopy
HalfLytely Bowel Prep System for Colonoscopy
The purpose of the this study was to compare the safety and efficacy of HalfLytely (2L NULYTELY + 20mg bisacodyl) to NULYTELY for preparation prior to colonoscopy.
- Trial name
- NCT00164164
- Testing
- HalfLytely, NuLytely
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Braintree Laboratories
Stool Microbiome
Evaluation of Stool Microbiome Using HyGIeaCare Prep
Stool samples will be collected before and during the HyGIeaCare procedure and the samples will be sent for microbiome evaluation.
- Trial name
- NCT04264923
- Testing
- HyGIeaCare Prep
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Colorectal Cancer
A Monocentric Study to Investigate a New Low Dose Oral Gut Cleansing Solution
A first study at one centre, with a new oral gut cleansing solution, NRL994, in patients who were going to have a colonoscopy. The study was to find out how well the new "Low Dose Bowel Prep" (LDBP) worked, and whether it was…
- Trial name
- NCT06597903
- Testing
- NRL994
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norgine