Clinical trials: Practice-based Evidence
Opioid Use Disorder (OUD)
HEALing Communities Study
This study will test the impact of implementing the Communities That Helping to End Addiction Long-term (HEAL) intervention on opioid overdose deaths within 67 highly affected communities with the goal of reducing opioid overdose…
- Trial name
- NCT04111939
- Testing
- Communities That HEAL, Wait-list control
- Where
- 4 sites in United States
- Volunteers
- 67 people
- Sponsor
- RTI International
Alcohol Use Disorder, Harm Reduction
Electronic Harm Reduction Treatment for Alcohol
The goal of this project is to transform a successful, face-to-face harm-reduction treatment (HaRT-A) into a digital format, creating eHaRT-A.
- Conditions
- Alcohol Use Disorder, Harm Reduction, Housing First (eg. Permanent Supportive Housing)
- Trial name
- eHaRT-A (NCT06702007)
- Testing
- eHaRT-A
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Washington
Risky Health Behavior, Drinking, Alcohol
STUN (STop UNhealthy) Alcohol Use Now! Implementing Evidence-Based Services for Unhealthy Alcohol Use in Primary Care
STUN Alcohol Use Now is an intervention designed to use primary care practice support services (practice facilitation) to help small to medium-size practices (10 or fewer providers) identify and provide services for people with…
- Conditions
- Risky Health Behavior, Drinking, Alcohol, Alcohol Use Disorder, Drinking, Binge
- Trial name
- STUN (NCT04317989)
- Testing
- Practice Facilitation
- Where
- 7 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Disease (CAD)
Improved Management of Patients With Recent-Onset Stable Chest Pain
In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused.
- Trial name
- IMPRO (NCT07476040)
- Testing
- IMPRO - Cross-Sectoral Care Model for Coronary Diagnostics
- Where
- 39 sites in Germany
- Volunteers
- 3,369 people
- Sponsor
- Philipps University Marburg
Psychological Distress
Practice-Based Evidence in Psychotherapy: A Multicentric Study From Ecuador
The goal of this observational study is to learn about the progress and outcomes of clients receiving psychotherapy for common mental health problems in Ecuador.
- Trial name
- CLIP_Ecuador (NCT07257848)
- Testing
- Psychological Intervention
- Where
- 11 sites in Ecuador
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Universidad de las Americas - Quito
Depression, Information Dissemination
Community Partners in Care is a Research Project Funded by the National Institutes of Health
CPIC is a community initiative and research study funded by the NIH. CPIC was developed and is being run by community and academic partners in Los Angeles underserved communities of color.
- Conditions
- Depression, Information Dissemination, Social Determinants of Health
- Trial name
- CPIC (NCT01699789)
- Testing
- Quality Improvement Program, Resources for Services Expert Team, Community Engagement and Planning Council
- Where
- United States
- Volunteers
- 1,246 people
- Sponsor
- RAND
Alcohol Consumption
Implementing Evidence-Based Mental Health Practices in Primary Care
This research study will examine the effectiveness of a brief, computerized motivational intervention plus treatment-as-usual to treatment-as-usual alone for treating alcohol misuse in Veterans presenting to primary care.
- Trial name
- NCT00996775
- Testing
- brief alcohol intervention, standard care
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Brain Tumor, Neurofibromatoses
Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")
In this study, the main goal is to implement and evaluate a novel, evidence-based psycho-educative program for children in oncological care. Patients are provided with booklets tailored to each specific stage of their treatment.
- Conditions
- Brain Tumor, Neurofibromatoses, Sarcoma, Leukemia
- Trial name
- NCT04474678
- Testing
- "My Logbook! - I know my way around!"
- Where
- 22 sites in Austria, Germany and 2 more
- Volunteers
- 240 people
- Sponsor
- Medical University of Vienna
Dental Pulp Exposure
Pulp Capping With Two Different Agents
The purpose of this study is to determine if MTA or calcium hydroxide are more effective as pulp capping agents
- Trial name
- MTA (NCT00812877)
- Testing
- Mineral Trioxide Aggregate, Calcium Hydroxide
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Early Childhood Caries, Oral Hygiene
Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries
Few educational oral health applications, directed to the preschool children under the age of six years are available world-wide.
- Conditions
- Early Childhood Caries, Oral Hygiene, Oral Health
- Trial name
- FU-APP (NCT05515510)
- Testing
- FU-APP, Oral health recommendations
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Evidence-Based Medicine
Evidence-Based Practice (EBP) Awareness Project: Peer-to-Peer Dissemination
The purpose of this study is to evaluate the effectiveness of the introduction of an EBP text for Nursing Research Council (NRC) members to use with RN staff to increase staff belief in, knowledge of and implementation of EBP in…
- Trial name
- NCT00636051
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Covid19
Community-engaged Approaches to Testing in Community and Healthcare Settings for Underserved Populations
The pandemic caused by the novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has resulted in substantial global morbidity and mortality including in Oklahoma and caused unprecedented interruptions…
- Trial name
- CATCH-UP (NCT04870307)
- Testing
- Dissemination and Implementation Research
- Where
- United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Hypertension, Diabetes
Optimize Audit and feedbaCk To Implement eVidence-based prAcTices in Primary Health carE
The investigators will use two phases of Multiphase Optimization Strategy (MOST) - preparation and optimization phases. In the preparation phase, Audit and Feedback (AnF) intervention will be prepared.
- Trial name
- ACTIVATE (NCT06480487)
- Testing
- Feedback provided face to face, Feedback provided by electronic mail, Feedback provided by researchers
- Volunteers
- 344 people
- Sponsor
- Southern Medical University, China
Backpain, Neck and Shoulder Pain
Implementation of Evidence-based Guidelines for Assessment and Counseling of Patients With Neck and Back Pain in Health Care Centers
The overall aim is to investigate the health outcomes and consequences, from an individual and a societal perspective, of adding licensed Manual Therapists as first-contact healthcare providers in Primary Health Care centers to…
- Trial name
- ALIGN (NCT07825116)
- Testing
- Manual terapeut management
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Karolinska Institutet
Autism
Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools
The primary goal of this study is to identify efficacious and cost effective intervention strategies that can improve academic and psychological outcomes for children with ASD, and can be feasibly be implemented at fidelity by…
- Trial name
- AIR-B II (NCT01724047)
- Testing
- Playground Intervention, STAT Intervention
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Health Resources and Services Administration (HRSA)
Mammography, Medical Overuse
A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women
This project aims to advance methodological and theoretical approaches for developing, selecting, refining, and piloting a multilevel de-implementation strategy to reduce the overuse of screening mammography in women aged ≥75…
- Conditions
- Mammography, Medical Overuse, Evidence-based Practice, Older Adults
- Trial name
- NCT07511621
- Testing
- Enhanced Usual Care (EUC), Multilevel De-Implementation Strategy
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Columbia University
Intervention Effectiveness, Practice-based Evidence
Strengthening Family Coping Resources Open Trials
Strengthening Families Coping Resources (SFCR) Open Trials completes the second stage of the National Institute on Drug Abuse's intervention development model by testing a new family, skills-based intervention involving pre-post…
- Conditions
- Intervention Effectiveness, Practice-based Evidence, Posttraumatic Stress Disorder
- Trial name
- SFCR (NCT01754610)
- Testing
- Strengthening Family Coping Resources (SFCR)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pit-and-Fissure Sealants
An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants
The purpose of this implementation science study is to determine whether Deliberative Loops are effective in increasing providers' adherence to the non-cavitated caries component of the American Dental Association's…
- Trial name
- DISGO (NCT04682730)
- Testing
- Deliberative Loop
- Where
- United States
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Childhood Obesity, Evidence-Based Practice
Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health
Community coalitions bring together residents and organizations to improve child health, but they may need support to identify and put research-supported strategies into practice.
- Conditions
- Childhood Obesity, Evidence-Based Practice, Food Systems, Food Policy
- Trial name
- NCT07804550
- Testing
- Catalyzing Communities, FICAS Implementation Intervention
- Where
- United States
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Kidney Disease, Chronic Kidney Insufficiency
Improving Evidence-Based Primary Care for Chronic Kidney Disease
Background: Chronic Kidney Disease (CKD) is under-recognized and under-treated in primary care offices and primary care physicians are generally not familiar with treatment guidelines.
- Conditions
- Chronic Kidney Disease, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency
- Trial name
- NCT01767883
- Testing
- Facilitated Clinical Decision Support, Clinical Decision Support Only
- Where
- United States
- Volunteers
- 27,000 people
- Sponsor
- American Academy of Family Physicians