Clinical trials: Practice-based Evidence
Alcohol Consumption
Implementing Evidence-Based Mental Health Practices in Primary Care
This research study will examine the effectiveness of a brief, computerized motivational intervention plus treatment-as-usual to treatment-as-usual alone for treating alcohol misuse in Veterans presenting to primary care.
- Trial name
- NCT00996775
- Testing
- brief alcohol intervention, standard care
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cocaine Use Disorder
Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project
The proposed work will investigate changes in brain signaling and cognitive functioning that support recovery from addiction, as well as use of pretreatment neurocognitive functioning to inform substance use treatment planning.
- Trial name
- WRAP (NCT03799341)
- Testing
- Prize-Based Contingency Management, Treatment As Usual Outpatient Substance Use Treatment
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Frontotemporal Dementia, Dementia
Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)
The protocol is organized into three Phases - In Phase I an online training program will be developed in "Care of Persons with Dementia in their Environments" (COPE) -an evidence-based bio-behavioral dementia program -using…
- Conditions
- Frontotemporal Dementia, Dementia, Multi-Infarct Dementia, Vascular Dementia
- Trial name
- NCT04165213
- Testing
- Care of Older Persons in their Environment (COPE) online module training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Decision Making
Practice Guidelines Grading Systems
Clinical practice guidelines (CPG) are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances.
- Trial name
- NCT00940290
- Testing
- Graded Clinical Recommendation
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Anxiety, Depression
Improving Adherence to Homework During Therapy
The purpose of this study is to expand Adhere.ly- a simple, HIPAA-compliant, web-based platform to help therapists engage clients in practicing therapeutic skills between sessions (homework) during mental health treatment by…
- Conditions
- Anxiety, Depression, Depression/Anxiety
- Trial name
- Adherely STTR (NCT05866185)
- Testing
- Therapy, Therapy + Adhere.ly
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of South Florida
Covid19
Community-engaged Approaches to Testing in Community and Healthcare Settings for Underserved Populations
The pandemic caused by the novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has resulted in substantial global morbidity and mortality including in Oklahoma and caused unprecedented interruptions…
- Trial name
- CATCH-UP (NCT04870307)
- Testing
- Dissemination and Implementation Research
- Where
- United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Health Behavior
Training LHDs to Disseminate Evidence-Based Interventions to Small Worksites
The proposed project will advance implementation science by comparing the effectiveness of different levels of technical support in an important but understudied community-based setting: local health departments.
- Trial name
- NCT03930420
- Testing
- Connect to Wellness
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Washington
Opioid Use Disorder (OUD)
HEALing Communities Study
This study will test the impact of implementing the Communities That Helping to End Addiction Long-term (HEAL) intervention on opioid overdose deaths within 67 highly affected communities with the goal of reducing opioid overdose…
- Trial name
- NCT04111939
- Testing
- Communities That HEAL, Wait-list control
- Where
- 4 sites in United States
- Volunteers
- 67 people
- Sponsor
- RTI International
Acute Respiratory Failure
METEOR Think NIV Pilot
This study will pilot test three strategies designed to speed implementation of preventive post-extubation noninvasive ventilation (NIV): one control strategy (traditional online continuing medical education) and two novel…
- Trial name
- NCT04052542
- Testing
- Traditional online continuing education, Interprofessional education, Just-in-time education
- Where
- United States
- Volunteers
- 1,328 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anxiety Disorders
Parent Key Opinion Leaders to Increase Demand of Effective Treatments for Youth Anxiety
Despite research identifying effective treatments for youth anxiety, parents (and other primary caregivers) are unaware that some treatments are more effective than others.
- Trial name
- Project CHAT (NCT04929262)
- Testing
- Supporting Anxious Youth: Strategies for Caregivers
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Temple University
Pit-and-Fissure Sealants
An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants
The purpose of this implementation science study is to determine whether Deliberative Loops are effective in increasing providers' adherence to the non-cavitated caries component of the American Dental Association's…
- Trial name
- DISGO (NCT04682730)
- Testing
- Deliberative Loop
- Where
- United States
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh