Clinical trials: Practices
Urinary Tract Infections
Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial
It is well known that "over-treatment" of straightforward infections should be avoided as far as possible. Evidence-based data on non antibiotic treatment options for common conditions are therefore needed urgently.
- Trial name
- REGATTA (NCT03151603)
- Testing
- Arctuvan, Fosfomycin
- Where
- 47 sites in Germany
- Volunteers
- 398 people
- Sponsor
- University Medical Center Goettingen
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent)
An Opioid Prescribing Nudge
Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures.
- Conditions
- Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior
- Trial name
- OHS (NCT04069403)
- Testing
- Automated Reports on prescription patterns for their patients
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Duke University
Chronic Pain, Opioid Use
Reducing Opioid Use for Chronic Pain Patients Following Surgery
Patients with chronic pain are often prescribed long-term opioid therapy, despite the serious risks and growing concerns related to opioid use.
- Conditions
- Chronic Pain, Opioid Use, Postoperative Pain, Opioid Dependence
- Trial name
- RECOUP (NCT03675386)
- Testing
- Interventional Group, Control Intervention
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University Health Network, Toronto
Proctologic Practice During COVID-19
Proctologic Practice and Covid-19
Cross-sectional non-incentivized worldwide web survey. A worldwide survey of 1050 respondents showed that proctologic practice has been seriously affected by the pandemic.
- Trial name
- PROCTOLOCK (NCT04392245)
- Where
- Italy
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Low Back Pain
Implementation of a Best Practice Primary Health Care Model for Low Back Pain
POPULATION: Low back pain (LBP) is a major health problem commonly requiring health care. In Sweden, primary care professionals require an evidenced based model of care for LBP.
- Trial name
- BetterBack (NCT03147300)
- Testing
- Current routine practice, Multifaceted implementation of the BetterBack
- Where
- Sweden
- Volunteers
- 467 people
- Sponsor
- Linkoeping University
Frailty, Older People
Sense of Control in Frail Older Persons
The proposed study seeks to explore the lived experience of control and wellbeing of older people diagnosed with frailty within the care service provision in southern England.
- Conditions
- Frailty, Older People, Sense of Control
- Trial name
- CONtrol (NCT04503811)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Bournemouth University
Neoplasm
Current Practice Pattern and Effect of Training in Upper Endoscopic Biopsy
The optimal number of biopsy and the detection rate of neoplastic lesions are not established. The aim of this study is to assess the current practice pattern and effect of training in upper endoscopic biopsy.
- Trial name
- NCT02044536
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 1,208 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anesthesia, General
Clinical Practice of Inhalation Anesthesia With Sevoflurane in China
Until recently, there was a lack of understanding and consensus among Chinese anesthesiologists how they should practice general anesthesia with volatile anesthetics, since there was no standard of inhalation practice.
- Trial name
- NCT01715857
- Where
- 36 sites in China
- Volunteers
- 4,100 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Coronary Disease
Randomized Comparison of MynxGrip Vascular Closure Device and Manual Compression for Closure After Femoral Access Angiography. The Closure Devices Used in Every Day Practice Study, CLOSE-UP III Trial
Is the MynxGrip (test device) non-inferior to manuel compression (standard comparator) in the incidence of adverse access site related events in-hospital, at 30 days and at 6 months.
- Trial name
- CLOSE-UP III (NCT02237430)
- Testing
- MynxGrip, Manual compression
- Where
- Denmark
- Volunteers
- 869 people
- Sponsor
- Aarhus University Hospital Skejby
Non-specific Low Back Pain
Effect of Reassuring Information on Danish Workers Who Experience Low Back Pain in the Following Year.
RCT study of the effect of an educational-based intervention on low back pain-related outcomes concerning beliefs and behaviour.
- Trial name
- VRRPF (NCT01918228)
- Testing
- Talks about what science says about LBP
- Where
- Denmark
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Deprescriptions, Antidepressive Agents
Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy
The PARTNER study is a multicentre, two-arm, pragmatic cluster-randomised trial evaluating the impact of a focused and patient-centred cooperation between general practitioners (GPs) and community pharmacists (PARTNER…
- Conditions
- Deprescriptions, Antidepressive Agents, Antipsychotic Agents, Analgesics, Opioid
- Trial name
- PARTNER (NCT05842928)
- Testing
- PARTNER intervention, Control intervention
- Where
- 3 sites in Germany
- Volunteers
- 352 people
- Sponsor
- Ludwig-Maximilians - University of Munich
HELICOBACTER PYLORI INFECTIONS
Feasibility and Performance of FFPE qPCR for Detection of Clarithromycin Resistance in Helicobacter Pylori
This prospective observational study aims to evaluate the feasibility and performance of real-time PCR (qPCR) performed on formalin-fixed, paraffin-embedded (FFPE) gastric biopsies to detect Helicobacter pylori infection and…
- Trial name
- HED-2T (NCT07821294)
- Testing
- q-PCR on FFPE gastric biopsies
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Clinique Bizet
Evidence-Based Practice, Nurse's Role
Feasibility and Effectiveness of the Advancing Research and Clinical Practice Through Close Collaboration (ARCC)
The Institute of Medicine's (IOM) ambitious goal for at least 90% of clinical decisions to be evidence-based includes nursing interventions and practice.
- Trial name
- ARCC (NCT03269331)
- Testing
- CTEP EBP Immersion
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Acute Cholestatic Hepatitis
Emergent Laparoscopic Cholecystectomy With ICG Cholangiography
A consecutive case series report to share our experience in surgical outcome of patients who underwent emergency laparoscopic cholecystectomy guided by indocyanine green (ICG) fluorescence.
- Trial name
- ELG-ICGC (NCT06549881)
- Testing
- emergency laparoscopic cholecystectomy guided by indocyanine green (ICG) fluorescence
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Peking Union Medical College Hospital
Attitude Towards Minimal Invasive Dentistry
Dentists' Knowledge, Attitude and Practice Regarding Minimally Invasive Dentistry a Cross Sectional Comparative Study Between Two Governorates in Egypt
Some of the published researches indicate that many practicing dentists have not used the MID concepts yet in their clinics. They still use the surgical model of treatment despite the paradigm shift to the medical model.
- Trial name
- NCT06538805
- Testing
- Minimal invasive management of dental caries
- Volunteers
- 808 people
- Sponsor
- Cairo University
Kidney Disease, Chronic
An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis
This observational, prospective, multicenter study will describe the mean dose of Mircera (methoxy polyethylene glycol-epoetin beta) and the hemoglobin levels in patients with chronic kidney disease.
- Trial name
- NCT01318512
- Where
- Czechia
- Volunteers
- 340 people
- Sponsor
- Hoffmann-La Roche
Consciousness, Near Death Experience
Episodes of (Dis)Connected Consciousness in ICU Survivors
This single-center observational study aims to describe the incidence of episodes of connected consciousness and disconnected consciousness (including near-death experience (NDE) and out-of-body experiences) in patients who…
- Conditions
- Consciousness, Near Death Experience, ICU, Critical Illness
- Trial name
- CONSCIOUS-ICU (NCT07048951)
- Testing
- The Near-Death Experience Content (NDE-C) scale, Threat perception measure, Interview about the participant's memories of the ICU
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University of Liege
Diabetes, Hypertension
Quality IQ Patient Simulation Physician Practice Measurement and Engagement
This study will test the quality of physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and feedback.
- Conditions
- Diabetes, Hypertension, Depression, Osteoarthritis
- Trial name
- Q-IQ (NCT03800901)
- Testing
- Continuing Medical Education, Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Critical Illness, Near-Death Experience
Near-death Experience in ICU Survivors
This observational study aims to describe the incidence of near-death experience (NDE) in patients who survived a critical illness.
- Trial name
- NCT04279171
- Testing
- Greyson NDE scale, DES dissociation scale, WHOQOL-SRPB
- Where
- Belgium
- Volunteers
- 126 people
- Sponsor
- University of Liege
Iron Deficiency Anemia, Coronary Artery Disease
Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease
The goal of this observational study is to learn how well Ferretab® comp. works and how safe it is for adults with iron deficiency anemia and cardiovascular disease who are receiving treatment as part of their usual medical care.
- Conditions
- Iron Deficiency Anemia, Coronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PROMETHEUS (NCT07753031)
- Where
- 5 sites in Russia
- Volunteers
- 389 people
- Sponsor
- Alcea
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