Clinical trials: Practices
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Pain, Advanced Cancer
Sativex® for Relieving Persistent Pain in Patients With Advanced Cancer
This 9-week study aimed to determine the efficacy, safety, and tolerability of nabiximols (Sativex®) as an adjunctive treatment, compared with placebo in relieving uncontrolled persistent chronic pain in participants with…
- Trial name
- SPRAY III (NCT01361607)
- Testing
- Nabiximols
- Where
- 68 sites in United States, Bulgaria and 8 more
- Volunteers
- 399 people
- Sponsor
- Jazz Pharmaceuticals
Venous Thromboembolism
Edoxaban Treatment in Routine Clinical Practice in Patients With Venous Thromboembolism in Europe
According to current guidelines, duration of anticoagulant treatment after a venous thromboembolic event varies from 3 months to indefinite treatment depending on the estimated risks of venous thromboembolism (VTE) recurrence and…
- Trial name
- ETNA-VTE (NCT02943993)
- Testing
- Edoxaban
- Where
- Germany
- Volunteers
- 2,809 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Physician Rounds, Communication
Timing of Physician Rounds for Antepartum Patients
This study will include patients admitted to the Antepartum service at Duke University Hospital, many of whom are managing high-risk pregnancies that require extended hospital stays and frequent physician interactions.
- Trial name
- NCT07215507
- Testing
- Discovery Rounding, Standard Rounding
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Human Papillomavirus
Normalizing HPV Vaccination in Preteens With a Serious Video Game
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States and causes genital warts and cancers in both females and males.
- Trial name
- NCT04627298
- Testing
- educational video game for preteens to support HPV vaccination
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of North Carolina, Chapel Hill
Multiple Myeloma
Pom-dex Versus Pom-Cyclo-dex in MM Patients With Biochemical or Clinical Relapse, During Lena Maintenance Treatment
The combination lenalidomide plus low-dose dexamethasone (Rd) is an active treatment for Multiple Myeloma (MM) patients, both at diagnosis and at relapse.
- Trial name
- PO-3887 (NCT03440411)
- Testing
- Pomalidomide, Cyclophosphamide, Dexamethasone
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- Fondazione EMN Italy Onlus
Alcoholic Intoxication, Automobile Accident
Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers
The new recreational marijuana markets are contributing to polysubstance-impaired driving and other harms, especially when marijuana is used in combination with alcohol, by selling marijuana to obviously-intoxicated customers.
- Conditions
- Alcoholic Intoxication, Automobile Accident, Cannabis
- Trial name
- NCT06235632
- Testing
- Policy and Training Intervention, Usual and Customary Policy and Training (UC-PT) (Control) Condition
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Klein Buendel, Inc.
Osteoporosis
Vitamin D Supplementation in Postmenopausal Women With Osteoporosis: Proposal of a Therapeutic Regimen in Practice
The vitamin D deficiency (25OHD) is very common and affects about 80% of the population of French osteoporotic women over 50 years [5]. It contributes significantly to bone fragility and consequently the risk of fracture.
- Trial name
- VITAD (NCT02518763)
- Testing
- Vitamin D3, 100 000 IU weekly, 4 times, 25 OH vitamin D serum concentration measurements
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Behavior Disorders
Remote Training in Rural Schools
Rural areas have fewer, and less well trained, health care providers than non-rural areas. Schools have become more involved in the delivery of mental health services and hold great potential for increasing access to children and…
- Trial name
- NCT05034198
- Testing
- Coping Power Program (CPP), Cognitive behavioral therapy (CBT) for Anxiety Treatment in Schools (CATS), Check-in/Check-out (CI/CO)
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Diagnostic Uncertainty
Targeted EHR-based Communication of Diagnostic Uncertainty in the ED
The goal of the clinical trial is to evaluate the preliminary effectiveness and the implementation feasibility of the Targeted EHR-based Communication about Uncertainty (TECU) strategy in improving the quality of care transitions…
- Trial name
- TECU (NCT06638021)
- Testing
- Targeted EHR-based Communication of Diagnostic Uncertainty (TECU)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Thomas Jefferson University
Prosthesis User, Amputation
Evaluating the Experience of Upper Limb Prosthesis Use
The goal is to understand the critical factors associated with outcome acceptance following upper limb loss. The investigators aim to develop a unified theoretical model that describes the psychosocial experience of upper limb…
- Conditions
- Prosthesis User, Amputation, Upper Limb Amputation at the Wrist, Upper Limb Amputation Above Elbow (Injury)
- Trial name
- NCT04855214
- Testing
- Qualitative Analysis
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Louis Stokes VA Medical Center
Tobacco Dependence
Provider and Peer Delivered Youth Smoking Intervention
The purpose of this study was to determine whether a pediatric practice-based smoking prevention and cessation intervention increases abstinence rates among adolescents.
- Trial name
- NCT00435344
- Testing
- Pediatric Practice-Based Smoking Intervention
- Where
- United States
- Volunteers
- 2,711 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Low Back Pain
Low Back Pain Among Care-seeking Families in General Practice
Background Low back pain (LBP) is the largest cause of years lived with disability worldwide and often associated with low quality of life, inability to work and low physical activity levels.
- Trial name
- NCT04148144
- Testing
- No intervention included
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Aalborg University
Autoimmune Diseases, Checkpoint Inhibitor
Checkpoint Inhibitors in Patients With Cancer and Underlying Autoimmune Disease
Patients with cancer and concurrent autoimmune diseases (AID) have been universally excluded from clinical trials evaluating immunotherapy.
- Conditions
- Autoimmune Diseases, Checkpoint Inhibitor, Immunotherapy
- Trial name
- CIAD (NCT04805099)
- Testing
- Checkpoint inhibitor
- Where
- Greece
- Volunteers
- 126 people
- Sponsor
- Hellenic Cooperative Oncology Group
Depression
Collabri Flex - Effect of Collaborative Care for People With Depression in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with depression in general practice, based on past experience gained in the Collabri Project.
- Trial name
- Collabri Flex (NCT03113201)
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 389 people
- Sponsor
- Amager Hospital
Social Representations of Infectious Diseases
Medical Practices and Representations of People From Haiti in French Guiana
This is an observational, cross-sectional, qualitative study of the population of Haitian origin living in French Guiana and the professionals working with them
- Trial name
- NCT06539130
- Where
- French Guiana
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Physicians' Practice Patterns, Coronary Heart Disease
From Research to Practice - Lipid Management for Low HDL-Cholesterol
The overall purpose of this project is to improve the clinical outcomes of veterans with ischemic heart disease (IHD) through implementation of evidence-based lipid management, with a particular focus on veterans whose primary…
- Trial name
- NCT00057044
- Testing
- education and reminder
- Where
- United States
- Volunteers
- 11,700 people
- Sponsor
- US Department of Veterans Affairs
Sign Language Skills, Teacher Practice
Strategic and Interactive Signing Instruction Experiment
This RCT study involves teachers divided into an experimental group and a control group. Teachers in the experimental group will receive SISI training to support the sign language development of deaf children, while those in the…
- Trial name
- NCT06729164
- Testing
- Strategic and Interactive Signing Instruction, Business-As-Usual Instruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Tennessee, Knoxville
Pain, Advanced Cancer
Sativex® for Relieving Persistent Pain in Participants With Advanced Cancer
This 9-week study aimed to determine the efficacy, safety and tolerability of nabiximols (Sativex®) as an adjunctive treatment, compared with placebo in relieving uncontrolled persistent chronic pain in participants with advanced…
- Trial name
- NCT01262651
- Testing
- Nabiximols
- Where
- 72 sites in United States, Belgium and 10 more
- Volunteers
- 397 people
- Sponsor
- GW Pharmaceuticals Ltd
Chronic Kidney Disease, Stage 4 (Severe), Chronic Kidney Disease, Stage 5
Impact of PREMs in the Shared Decision Process for Renal Replacement Treatment Methods.
The French "my health 2022" plan is the first bundled payment initiative for stage 4 and 5 chronic kidney disease (CKD) pathway with the aim to improve the quality of care and promote a multi professional collaboration for a more…
- Trial name
- PEACE (NCT06819345)
- Testing
- Survey form
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
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