Clinical trials: Practices
Obesity
Food and Nutrition Education in Quilombolas Communities With Food Insecurity: Multi-sector Intervention
To optimize the food security in quilombolas communities with high prevalence of food insecurity and obesity, the present study proposes to test a multi-sector intervention including agriculture sectors, health professionals and…
- Trial name
- NCT02489149
- Testing
- Multi-sector interventions, Control
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Federal University of Rio Grande do Sul
Slow Labour Progress
Labour Augmentation by Means of Oxytocin - Obstetric Outcome and Women's Experiences
Slow labour progress is common in nulliparous women and is associated with childbirth complications and negative birth experiences. Oxytocin augmentation is widely used to treat slow labour despite associated risks for the fetus.
- Trial name
- NCT01263158
- Testing
- Expectancy of standard oxytocin treatment
- Where
- Sweden
- Volunteers
- 2,072 people
- Sponsor
- Göteborg University
Hemophilia A, Hemophilia B
Study of Surgical Practices in Patients With Haemophilia A or B Treated With an Extended Half-life Recombinant Factor VIII-Fc or IX-Fc (ELOCTA®, ALPROLIX®)
Haemophilia A and haemophilia B are inherited bleeding disorders resulting from the absence or deficiency of coagulation factors VIII and IX, respectively.
- Trial name
- CHALE (NCT06158334)
- Testing
- Describe the respective haemostatic efficacy of Elocta® for haemopilia A during surgical procedures, Describe the respective haemostatic efficacy of Alprolix® for haemopilia B during surgical procedures
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Sexual Risk Behavior for HIV-Infection
Effect Study of a Theory-Based Internet Intervention on Safe-Sex Practices
The purpose of this study is to examine the efficacy of a theory based, online tailored intervention on stimulating safe-sex practices among men who have sex with men (MSM).
- Trial name
- NCT00378885
- Testing
- Cognitive-behavioral tailored intervention
- Where
- Netherlands
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Public Health Service of Amsterdam
Burnout
Comparison of Two Artificial Intelligence Scribe Products on Pediatric Subspecialty Provider Wellness and Experience, Patient Satisfaction, and Efficiency.
The goal of this rapid, randomized quality improvement trial is to learn if implementing generative AI scribe software can enhance physician documentation efficiency and reduce burnout in outpatient providers at Children's…
- Trial name
- NCT07157943
- Testing
- Abridge AI Scribe, DAX Copilot
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Children's Healthcare of Atlanta
Pain, Procedural
Virtual Reality Goggle Utilization for Venipuncture Distraction
This is a randomized non-blinded trial evaluating the effect of virtual reality goggles on perceived pain and anxiety scores during venipuncture on hospitalized children ages 5-21.
- Trial name
- NCT04479735
- Testing
- Virtual Reality Goggles
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Asthma, Quality of Life
Quality of Life Assessment in Greek asthmatIc Patients Treated With the Fixed Dose Combination of Budesonide / Formoterol in Clinical Practice
The greater efficacy of combination therapy led to the development of fixed combination devices which simultaneously carry both glucocorticosteroid and a LABA (eg stable combinations of fluticasone-salmeterol…
- Conditions
- Asthma, Quality of Life, Satisfaction
- Trial name
- SKIRON (NCT03055793)
- Testing
- budesonide formoterol fixed combination
- Where
- Greece
- Volunteers
- 1,400 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Prostate Cancer
Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy
The purpose of this study is to evaluate if a VR headset and/or aromatherapy can be used to reduce patient pain, anxiety, and embarrassment during a transperineal biopsy (TPBx) compared to standard of care (SOC).
- Trial name
- NCT06296147
- Testing
- Virtual Reality Headset, Aromatherapy Patch, Standard of Care
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Pittsburgh
Dental Caries; Oral Health; Malocclusion
Dental Caries and Related Factors in 6-Year-Old Schoolchildren in Chile: National Evidence for Assessment and Decision-Making (6yOH-Chile)
Dental caries is the most prevalent chronic non-communicable disease in childhood worldwide. In Chile, the last nationally representative oral health survey was conducted in 2007 and reported a caries experience prevalence of…
- Trial name
- 6yOH-Chile (NCT07863947)
- Where
- Chile
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Anemia of Chronic Kidney Disease
Vafseo Outcomes In-Center Experience
This trial is an investigator-initiated, multi-center, randomized (1:1), open-label, active-controlled, pragmatic study of the safety of vadadustat administered three times per week for the treatment of anemia in in-center…
- Trial name
- VOICE (NCT06520826)
- Testing
- Vadadustat, Erythropoiesis Stimulating Agent
- Where
- 5 sites in United States
- Volunteers
- 2,200 people
- Sponsor
- USRC Kidney Research
Inherited Cardiac Conditions
Families' Experiences of Paediatric ICC Diagnosis
This study aims to further understand the experiences of children, their parents and siblings around the time when the child and their family are informed of a diagnosis of an inherited cardiac condition (ICC).
- Trial name
- FEPICCD (NCT02737111)
- Testing
- Initial Screening Process, Information and Informed Consent, Interview
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Vascular Disease, Peripheral, Amputation
Vascular Amputee Physical Performance Qualitative (VAmPP-Q) Study
Background: Peripheral arterial disease (PAD) is the main cause of amputation to the lower limb within the UK, affecting over 20% of adults older than 70 years.
- Conditions
- Vascular Disease, Peripheral, Amputation, Physical Disability
- Trial name
- VAmPP-Q (NCT05860764)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Leicester
Neoplasms, Epilepsy
Integrative and Complementary Health Practices (PICS)
Complementary medicine, considered an unconventional approach, is performed in conjunction with conventional medicine. In Brazil, Integrative and Complementary Practices in Health have been inserted by the National Ordinance of…
- Trial name
- PICS (NCT04152109)
- Testing
- Without laying on of hands subgroup, Laying on of hands without Spiritual connection, Laying on of hands by Spiritual "Passe"
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal do Triangulo Mineiro
Juvenile Idiopathic Arthritis (JIA)
Tofacitinib in Juvenile Idiopathic Arthritis
This study aims to evaluate, using real-world clinical practice data, the efficacy of tofacitinib in improving the clinical control of juvenile idiopathic arthritis (JIA) after 12 months of treatment.
- Trial name
- NCT07211932
- Testing
- Tofacitinib
- Where
- 7 sites in Spain
- Volunteers
- 58 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Breast Cancer
Initial CDK 4/6 Inhibitor Plus Endocrine Therapy Versus Initial Chemotherapy in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer
A multi-center, real world study to evaluate the clinical outcomes between initial CDK 4/6 Inhibitor plus endocrine therapy and initial chemotherapy in HR positive, HER2 negative unresectable or metastatic breast cancer.
- Trial name
- NCT06344793
- Where
- China
- Volunteers
- 608 people
- Sponsor
- Fudan University
Immunisation Anxiety Related Reaction
Feasibility of Implementation of CARD for School-Based Immunizations
A multi-faceted knowledge translation intervention - The CARD (C-Comfort, A-Ask, R-Relax, D-Distract) System - was developed to improve the vaccination experience of students at school.
- Trial name
- NCT03948633
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Post Traumatic Stress Disorder PTSD
Effectiveness of Informational and Educational Tools to Improve the Experience of Relatives of ICU Patients. RELIEF, a Platform Trial
The admission of a patient to an intensive care unit (ICU) is associated with high levels of acute stress, anxiety, and depression among relatives, as well as extreme emotions such as fear, guilt, distress, and helplessness.
- Trial name
- RELIEF (NCT06851884)
- Testing
- Standard of Care (SOC), Video capsules, Cartoon
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rheumatoid Arthritis
PREVALENCE OF Anti-CCP POSITIVITY AND SUBCLINICAL SIGNS OF INFLAMMATION IN PATIENTS WITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS
Non-interventional, prospective, observational study to assess the relative risk of anti-CCP positive patients to develop (subclinical) signs of inflammation in accordance with early Rheumatoid Arthritis (RA) in a population…
- Trial name
- PANORA (NCT03267147)
- Testing
- no intervention is given
- Where
- Germany
- Volunteers
- 986 people
- Sponsor
- Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Echocardiography
A Prospective Surveillance Trial to Evaluate the Safety of Optison in Clinical Practice.
This prospective surveillance trial will gather safety information for Optison when it is used in routine practice.
- Trial name
- OSSAR (NCT00730964)
- Testing
- Perflutren Protein-Type A Microspheres Injectable Suspension, United States Pharmacopeia (USP)
- Where
- United States
- Volunteers
- 1,039 people
- Sponsor
- GE Healthcare
Educational Problems
Cardiovascular Fellow-in-training Feedback on Virtual and Simulator-based Learning Experience in A Low to Middle Income Country
Virtual and simulatorbased learning is not widely available in LMIC. It is imperative to analyze feedback of CV fellow-in-training regarding this mode of learning before large scale implementation.
- Trial name
- NCT04984564
- Testing
- None. As this was an observational study.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
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