Clinical trials: Pre Eclampsia
Hypertension With Pregnancy
Evaluation of Psychological Status in Pregnant Women Complaining of Hypertension With Pregnancy
This study is a case controlled study comparing mental health status and some psychological impacts between two groups of patients first group is pregnant women without any other medical disorder during pregnancy,the second group…
- Trial name
- NCT03503383
- Testing
- Patient Health Questionnaire-9, Generalized Anxiety Disorder Scale (GAD-7)
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Fetal Growth Restriction (FGR), Preeclampsia
Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome
The goal of this prospective cohort study is to examine how different parameters of assisted reproductive technologies (ART) are associated with the perinatal outcome in individuals with singleton or multiple gestations.
- Conditions
- Fetal Growth Restriction (FGR), Preeclampsia, Stillbirth, Placenta Previa
- Trial name
- NCT06918236
- Where
- 6 sites in Bulgaria, Greece and 1 more
- Volunteers
- 12,084 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Pre-Eclampsia, Gestational Diabetes
Lifestyle Intervention for Women With Recent Pre-eclampsia or Gestational Diabetes Mellitus ('Mom's Healthy Heart')
The aim of this pilot intervention study is to develop and test a tailored web-based lifestyle modification program for women with recent preeclampsia or gestational diabetes. Women will start the study 3-15 months postpartum.
- Trial name
- NCT03993145
- Testing
- Web-based lifestyle intervention
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- Norwegian University of Science and Technology
Pre-Eclampsia, Gestational Hypertension
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.
- Conditions
- Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced
- Trial name
- NCT03298802
- Testing
- Hydrochlorothiazide 50mg Tablet
- Where
- 2 sites in United States
- Volunteers
- 453 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Congenital Heart Disease
Preeclampsia and Fetal Heart Malformations: Looking to Maternal Heart
The goal of this study is to describe the maternal hemodynamic parameters detected by UltraSonic Cardiac Output Monitor (USCOM®) in women carrying a fetus with a congenital heart disease (CHD) and to possibly describe an…
- Trial name
- MAMAH (NCT07092644)
- Testing
- UltraSonic Cardiac Output Monitor (USCOM®)
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pregnancy-Associated Hypertension, Gestational Hypertension
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
High blood pressure during or after pregnancy (such as preeclampsia, gestational hypertension, eclampsia, or Hemolysis, Elevated Liver enzymes, and Low Platelet (HELLP) syndrome) raises a mother's risk of heart disease later in…
- Conditions
- Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia
- Trial name
- AW2H (NCT07778966)
- Testing
- Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Morbid, Preeclampsia
Use of Impedance Cardiography to Decrease the Risk of Pre-eclampsia in Obese Patients
To determine if the use of impedance cardiography can identify appropriate medications for use in treating morbidly obese patients to decrease the risk of preeclampsia.
- Trial name
- NCT03105661
- Testing
- Labetalol Hydrochloride 200 mg, NIFEdipine 60 mg, Atenolol 25 mg
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Cannabis Use Disorder, PREG1
The Influence of in Utero Cannabis Exposure on Neonatal Brain Morphology and Structural Connectivity
Cannabis is the most commonly used drug by women during pregnancy with an estimated prevalence of use in Colorado of 5.7%. THC and its metabolites freely cross the placenta and blood-brain barrier to bind with cannabinoid…
- Conditions
- Cannabis Use Disorder, PREG1, Drug Use, Fetal Exposure During Pregnancy
- Trial name
- NCT03718520
- Testing
- no intervention, this is a purely observational study
- Where
- 2 sites in United States
- Volunteers
- 168 people
- Sponsor
- University of Colorado, Denver
Preeclampsia, Proteinuria
Comparison of Catheterized and Clean Catch Urine Specimens for Protein/Creatinine Ratio in Preeclampsia Evaluation
The purpose of this prospective study was to examine whether protein/creatinine ratios in catheterized urine specimens correlate to clean catch specimens in pregnant patients being evaluated for preeclampsia.
- Conditions
- Preeclampsia, Proteinuria, Hypertension, Pregnancy
- Trial name
- UPREE (NCT00654771)
- Testing
- urine collection
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Pittsburgh
Postoperative Pain
A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients
This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively.
- Trial name
- NCT02619799
- Testing
- intrathecal magnesium sulphate,, Intrathecal midazolam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rangaraya Medical College
Pre-Eclampsia, Morbid Obesity
Non-invasive Versus Invasive Blood Pressure Measurement in the Morbidly Obese Parturient With Severe Preeclampsia
The study will compare agreement of invasive blood pressure measurements with non-invasive blood pressure measurements measured with a conical blood pressure and large standard upper arm rectangular cuff in morbidly obese…
- Conditions
- Pre-Eclampsia, Morbid Obesity, Parturient, Blood Pressure
- Trial name
- NCT03222414
- Testing
- Non-invasive BP recording with conical Ultracheck Curve BP cuff, Non-invasive BP recording with traditional cylindrical BP cuff, Direct invasive arterial pressure
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center
Sickle Cell Disease, Pregnancy Related
LEARNER- Low dosE AspiRiN prEterm tRial (Angola)
This study is being conducted to evaluate the safety and effect of starting daily use of low dose (100 mg) aspirin in pregnant women with sickle cell disease, who are being followed in two county hospitals in Angola, in the first…
- Conditions
- Sickle Cell Disease, Pregnancy Related, Pregnancy Complications, Pre-Eclampsia
- Trial name
- LEARNER (NCT06417411)
- Testing
- Aspirin 100mg
- Where
- Angola
- Volunteers
- 450 people
- Sponsor
- Instituto Nacional de Investigacao em Saude, Angola
Preeclampsia, Hypertensive Disorder of Pregnancy
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
This is a single site, single-blinded parallel randomized control trial that investigates a multi-level intervention to improve postpartum blood pressure in women with hypertensive disorder pregnancy.
- Conditions
- Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications
- Trial name
- HHD (NCT05655936)
- Testing
- Heart Health Doula Intervention Program, Usual Care
- Where
- United States
- Volunteers
- 454 people
- Sponsor
- University of Pittsburgh
Hypertension, Pregnancy-Induced
Evaluation of an Information Pamphlet for Postpartum Women That Had a Hypertensive Pregnancy
It is known that preeclampsia is a risk factor for cardiovascular diseases, diabetes, chronic hypertension, nephropathy and thromboembolism.
- Trial name
- NCT02523781
- Testing
- information pamphlet
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Hypertensive Disorder
Use of a Cloud-connected Remote Blood Pressure Monitoring Program During the Postpartum Period for Hypertensive Women
Hypertensive disorders (HD), including preeclampsia, gestational hypertension, chronic hypertension, and chronic hypertension with superimposed preeclampsia, affect around 10-20% of pregnant women in the United States and are…
- Trial name
- BP-ME (NCT06096701)
- Testing
- Blood pressure cuff
- Where
- United States
- Volunteers
- 421 people
- Sponsor
- University of South Carolina
Autism Spectrum Disorder, Asthma
Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)
FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social…
- Conditions
- Autism Spectrum Disorder, Asthma, Executive Dysfunction, Emotional Problem
- Trial name
- NCT03269110
- Testing
- SRS 2, CBCL, BRIEF-P
- Where
- 58 sites in Australia, Canada and 2 more
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Postpartum Preeclampsia, Hypertension in Pregnancy
Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial
Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.
- Trial name
- NCT05309460
- Testing
- Labetalol Oral Tablet, NIFEdipine ER
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Nebraska Methodist Health System
Pregnancy Diabetic
Predictive Value of Fetal Modified Myocardial Performance Index for Adverse Perinatal Outcomes in Late Onset Preeclampsia and Diabetes Mellitus
High-Risk Pregnancies complicated by gestational diabetes mellitus (GDM) and preeclampsia (PE) represent a significant global health challenge, affecting approximately 15-20% of all pregnancies.
- Trial name
- NCT07811050
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preeclampsia, Premature Birth
Cohort Study on the Levels of Placental Growth Factor and Nucleosomes in Early Pregnancy and Adverse Pregnancy Outcomes
Objective: This study aims to investigate the association between maternal serum placental growth factor (PLGF) and nucleosome levels in early pregnancy and adverse pregnancy outcomes, and to evaluate their predictive value for…
- Conditions
- Preeclampsia, Premature Birth, Fetal Growth Restriction, Recurrent Miscarriage
- Trial name
- NCT07841197
- Testing
- Measurement of plasma nucleosome and placental growth factor (PLGF) levels
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Suspected Placental Dysfunction, Ruled Out, Pregnancy Complications
Interest of sFlt1/PlGF Ratio at Obstetric Emergencies
In patients with suspected placental vascular disease who do not require hospitalization, the use of the sFlt-1 (Soluble FMS like tyrosin-kinase-1)/PlGF (Placental Growth Factor)/ assay can most likely help teams to define the…
- Conditions
- Suspected Placental Dysfunction, Ruled Out, Pregnancy Complications, Pre-Eclampsia
- Trial name
- AngioCHIC (NCT04170660)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil