Clinical trials: Pre Eclampsia
Overweight and Obesity, Insulin Resistance
DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study)
Women with excess adiposity while pregnant are more likely to develop gestational diabetes and high blood pressure during pregnancy than women of healthy weights.
- Conditions
- Overweight and Obesity, Insulin Resistance, Diabetes, Gestational, Hypertension in Pregnancy
- Trial name
- NCT00865683
- Testing
- DHA Supplements
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Preeclampsia, Nurse's Role
Preeclamptic Pregnancy Care Education
The aim of this study is to evaluate the effect of simulation training in nurses and midwives on knowledge and self-efficacy regarding preeclamptic pregnancy care.
- Trial name
- NCT04915794
- Testing
- Simulation of preeclamptic pregnancy care
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Istanbul University - Cerrahpasa
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Severe Pre-eclampsia
Nitroglycerin Versus Labetalol in Acute Severe Pre-eclampsia
Two hundred patients with severe PE were admitted prepartum to the ICU to stabilize blood pressure. They were randomly assigned to one of two groups (100 in each group): Group N received nitroglycerine intravenous infusion in a…
- Trial name
- NCT05310929
- Testing
- Labetalol and Glyceril trinitrate
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypertension, Pregnancy-Induced, Hypertension, Essential Hypertension
Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy
Background: 1. Burden: Hypertensive disorders of pregnancy, including preeclampsia, complicate up to 10% of pregnancies worldwide, constituting one of the greatest causes of fetal growth restriction, preterm birth, low birth…
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension, Essential Hypertension, Hypertension; Pre-Eclampsia, Hypertension in Pregnancy
- Trial name
- NCT03858595
- Testing
- Self monitoring of blood pressure using Health Gauge Device and monthly monitoring of weight gain
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Preeclampsia
Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development
Pregnant mothers who develop high blood pressure and other vascular problems (preeclampsia) deliver babies with increased neonatal health problems, which include lung disease and vascular complications, later in life.
- Trial name
- NCT02639676
- Testing
- Diffusion Lung Capacity (DLCO), Vascular Challenge, Video Imaging, Specimen Collections
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Indiana University
Pre-Eclampsia
Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension
In 2017, the American College of Cardiology and the American Heart Association changed the diagnostic criteria for hypertension in non-pregnant adults.
- Trial name
- NCT04908982
- Testing
- Aspirin 81mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Eastern Virginia Medical School
Anemia in Pregnancy, Preeclampsia
A Retrospective Analysis of Neevo®/Neevo®DHA Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
This study is a multi-site, retrospective chart review to determine the effect of Neevo® or Neevo®DHA (with higher folate and B12) versus standard prenatal vitamins on hemoglobin (Hgb) levels in pregnant women throughout the…
- Trial name
- NCT01062958
- Testing
- Neevo® (a medical food), Prenatal vitamins (≤1mg folic acid, 27 - 35mg iron, and ≤12mcg vitamin B12)
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Preeclampsia, Aspirin
Low Dose Aspirin Alerts in High-Risk Pregnancies
The goal of this study is to assess the effect of an electronic health record (EHR) clinical decision support tool, also known as a best practice alert (BPA), on healthcare provider recommendations for low dose aspirin use in a…
- Conditions
- Preeclampsia, Aspirin, Clinical Decision Support Systems, Economics, Behavioral
- Trial name
- NCT05802940
- Testing
- Electronic health record best practice alert
- Where
- United States
- Volunteers
- 830 people
- Sponsor
- Geisinger Clinic
Small for Gestational Age, Infant, Very Low Birth Weight
Effect of Low Dose Aspirin on Birthweight in Twins: The GAP Trial.
Low-dose aspirin started in the first-trimester has been associated with a decrease of preeclampsia, fetal growth restriction and preterm birth in high-risk pregnancies.
- Conditions
- Small for Gestational Age, Infant, Very Low Birth Weight, Fetal Growth Retardation, Preeclampsia
- Trial name
- GAP (NCT02280031)
- Testing
- Acetylsalicylic Acid
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Hypertension, Morality
Mortality Outcome of Controlled Hypertension
This review focuses on the assumption of mortality outcome of participants remaining label hypertension care is adequately managed when pressure targets are met with both qualitative and quantitaive method.
- Conditions
- Hypertension, Morality, Death, Pre-Eclampsia
- Trial name
- MOCH1 (NCT07187596)
- Where
- Thailand
- Volunteers
- 2,547 people
- Sponsor
- DejthidaNathaphong
Preeclampsia
Hydroxychloroquine in Prevention of Preeclampsia
Pre-eclampsia complicates up to 8% of pregnancies and is a major contributor to maternal mortality and morbidity The only effective treatment is delivery, which leads to significant neonatal morbidity and mortality if carried out…
- Trial name
- NCT04755322
- Testing
- Hydroxychloroquine, Folic acid, Low-dose aspirin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Postpartum Hemorrhage, Postpartum Depression
Postpartum Video Education in High Risk Populations
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Depression, Postpartum Sepsis, Postpartum Preeclampsia
- Trial name
- NCT06310720
- Testing
- Video Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pre-Eclampsia
Maternal and Neonatal Outcome in Severe Preeclampsia
In normal pregnancy the spiral arteries in the placental bed are invaded by trophoblast, which becomes incorporated into the vessel wall and replaces the endothelium, muscular layer and neural tissue
- Trial name
- NCT04126122
- Testing
- Ultrasonography to assess fetus and mother
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Endothelial Function (FMD), Preeclampsia
Identifying Biomarkers for Endothelial Dysfunction in Women With Preeclampsia
Every pregnancy has a major impact on a woman's heart and blood vessels due to changes required by the body to maintain proper blood flow between mother and foetus.
- Conditions
- Endothelial Function (FMD), Preeclampsia, Retinal Vessels
- Trial name
- DAISY (NCT07084727)
- Testing
- Arterial stiffness, Flow-meditad dilatation, Dynamic retinal vessel analyzer
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Preeclampsia
Maternal Serum Stathmin-1 Levels in Preeclampsia
The goal of this observational study is to investigate maternal serum Stathmin-1 levels in pregnancies affected by preeclampsia compared to healthy gestations. The main questions it aims to answer are: 1.
- Trial name
- MSSLP (NCT06481683)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Burak Yücel Special Clinic
Pre-Eclampsia; Complicating Pregnancy, Blood Loss
Blood Loss and Preeclampsia
Study of blood loss in preeclamptic patients using mathematical formulae
- Conditions
- Pre-Eclampsia; Complicating Pregnancy, Blood Loss, Coagulation Disorder
- Trial name
- NCT04777097
- Testing
- Blood sample
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Eclampsia Preeclampsia
Magnesium and Platelet Function Testing
Magnesium has built up the reputation of a 'natural calcium antagonist'. However, the exact effect of magnesium on coagulation and more specifically on platelet function is still disputed.
- Trial name
- MgCedVD (NCT03143647)
- Testing
- Collect a study-specific blood sample of healthy subjects
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Pre-Eclampsia
Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia
The purpose of this study is to compare the effect of albumin versus routine care on hemodynamic response and stability in pre-eclamptic patients during cesarean delivery.
- Trial name
- NCT06107335
- Testing
- Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pre-Eclampsia
Correlation Between Changes in Liver Stiffness and Preeclampsia as Shown by Fibroscan
Compare the Fibroscan results of preeclamptic women to normal controls and to find out if the changes are reversible after labor. Materials and Methods
- Trial name
- NCT03299777
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Western Galilee Hospital-Nahariya