Clinical trials: Pre Eclampsia
Hypertensive Disorder of Pregnancy, Pre-Eclampsia
Optimal Blood Pressure Treatment Thresholds Postpartum
The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control…
- Conditions
- Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia
- Trial name
- NCT06069102
- Testing
- Usual care, Tight blood pressure control
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Alisse Hauspurg
Preeclampsia, Eclampsia
uChek Pilot Study for Urinalysis in the Antenatal Care Setting
A prospective observational study to test the feasibility of smartphone enabled uChek urinalysis device to detect biomarkers (protein, microalbumin and protein:creatine ratio) in urine, indicative of preeclampsia/eclampsia at…
- Conditions
- Preeclampsia, Eclampsia, Pregnancy, Proteinuria
- Trial name
- uChekBangla (NCT02256995)
- Testing
- uChek
- Where
- Bangladesh
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Maternova Research
Preeclampsia
Vitamin D Therapy to Prevent Recurrent Preeclampsia in High-Risk Pregnancies
The goal of this clinical trial is to determine whether vitamin D supplementation can reduce the recurrence of preeclampsia in pregnant women with a previous history of preeclampsia.
- Trial name
- NCT07717931
- Testing
- Vitamin D (Cholecalciferol )
- Where
- Pakistan
- Volunteers
- 146 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Preeclampsia
Progesterone in Expectantly Managed Early-onset Preeclampsia
Preeclampsia is a disorder of widespread vascular endothelial malfunction and vasospasm that occurs after 20 weeks' gestation and can present as late as 4-6 weeks postpartum
- Trial name
- NCT04077853
- Testing
- 17 Hydroxyprogesterone Capronate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Preeclampsia
Study to Determine if Serum BNP Levels Are Elevated in Pregnant Women With Pre-Eclampsia
Preeclampsia is a common disease state occurring in the third trimester of pregnancy, with an incidence of approximately 5-10% in the US.
- Trial name
- NCT00533871
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Ohio State University
Preeclampsia
the Implications of Pathogenesis of Pre-Eclampsia
Preeclampsia is a severe complication of human pregnancy. It occurs in 4-5% of all pregnancies and remains a leading cause of maternal and neonatal mortality and morbidity.
- Trial name
- NCT00154934
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Sleep Apnea, Obstructive
Correlation Between Preeclampsia and Positive for Obstructive Sleep Apnea Screening Test: STOPBANG Questionnaire
The purpose of this study is to find the correlation between high risk OSA (obstructive sleep apnea) patient, based on Stop-bang screening tool and preeclampsia
- Trial name
- NCT02800798
- Testing
- Preeclampsia positive
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Preeclampsia
Safety, Tolerability, and PK/PD of Telpegfilgrastim Injection in Non-pregnant Females of Childbearing
This is an open-label, single-arm, Phase Ⅰa clinical study designed to evaluate the safety, tolerability, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of multiple doses of Telpegfilgrastim Injection in non-pregnant…
- Trial name
- NCT06924385
- Testing
- Telpegfilgrastim Injection
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Xiamen Amoytop Biotech Co., Ltd.
Obesity, Morbid, Preeclampsia
Use of Impedance Cardiography to Decrease the Risk of Pre-eclampsia in Obese Patients
To determine if the use of impedance cardiography can identify appropriate medications for use in treating morbidly obese patients to decrease the risk of preeclampsia.
- Trial name
- NCT03105661
- Testing
- Labetalol Hydrochloride 200 mg, NIFEdipine 60 mg, Atenolol 25 mg
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Pre-Eclampsia
Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in Sudan
the investigators assume that magnesium sulphate for treating eclampsia can be safely reduced from 24 hours to shorter duration of therapeutic anticonvulsant effect for 12 hours.
- Trial name
- NCT03112551
- Testing
- Adminstration of magnesium Sulphate for treatment of eclampsia
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gadarif University
Pre-Eclampsia
Diagnostic Value of MicroRNA 210 In Preeclampsia
Pre-eclampsia is a disorder of pregnancy characterized by hypertension (defined as systolic blood pressure 140mmHg or diastolic blood pressure ⩾90 mmHg) and proteinuria (300 mg or greater in a 24 h urine specimen and/or protein…
- Trial name
- NCT03193554
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pre Eclampsia
Study of Coagulation Activation Markers and Pre Eclampsia
The primary purpose of the trial is to evaluate coagulation activator markers in patients with pre eclampsia compared to control (normal pregnancy) and to correlate these markers with the severity of the pathology.
- Trial name
- PRESTIGE (NCT01261351)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Lille
Pre-Eclampsia; Complicating Pregnancy, Antiphospholipid Syndrome in Pregnancy
Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure
The primary goal of this observational study is to learn about postpartum pulmonary artery pressure in women who suffered from Preeclampsia and Antiphospholipid Syndrome.
- Conditions
- Pre-Eclampsia; Complicating Pregnancy, Antiphospholipid Syndrome in Pregnancy, Pulmonary Hypertension
- Trial name
- NCT05679206
- Testing
- Echocardiography images, 24-hour ambulatory blood pressure monitoring
- Where
- Switzerland
- Volunteers
- 900 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Preeclampsia
Biomarkers and Preeclampsia Outcomes
Prospective, observational, monocentric, non-interventional study.
- Trial name
- REPORTS (NCT03801447)
- Where
- Tunisia
- Volunteers
- 600 people
- Sponsor
- Dacima Consulting
Pre-Eclampsia
Prediction of Early Pre-eclampsia From Maternal Factors, Biophysical and Biochemical Markers at First Trimester
The aims of this study are to develop algorithms based on a combination of maternal factors, uterine artery PI, MAP and serum biomarkers to estimate patient-specific risks for early Preeclampsia (PE) and to evaluate the screening…
- Trial name
- NCT02990767
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Preeclampsia
Assessment of Volume Status in Preeclampsia Post- SpinalAnasthesia:Utilizing Ultrasound " Evaluation of Lung and Inferior Vena Cava"
Primary aim Assess the accuracy and reliability of ultrasound evaluation of lung and inferior vena cava in determining volume status post-spinal anesthesia in pre-eclampsia patients.
- Trial name
- AComparative (NCT07514130)
- Testing
- Ultrasound lung, ultrasound for IVC diameter, Intrathecal bupivacane
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Menoufia University
Preeclampsia
Cornell University-Micronutrient Initiative Calcium Supplementation Study
The World Health Organization (WHO) now recommends prenatal calcium supplementation for prevention of preeclampsia in populations with inadequate dietary intake.
- Trial name
- MICA (NCT02238704)
- Testing
- Regimen A calcium and iron/folic acid, Regimen B calcium and iron/folic acid
- Where
- 16 sites in Kenya
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Cornell University
Pre-Eclampsia
Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia
Endothelial dysfunction and defective placental vascularization are hypothesized to be significant causes of preeclampsia. In preeclampsia, due to vascular endothelial dysfunction, vasoconstriction and platelet activation can…
- Trial name
- ASPERIN (NCT03893630)
- Testing
- Acetylsalicylic Acid 81 mg, Acetylsalicylic Acid 162 mg, Control
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- John O'Brien, MD
Weight Loss, Postpartum Weight Retention
Postpartum Weight Loss for Women at Elevated Cardiovascular Risk
The aim of this study is to test the feasibility and effectiveness of a 16-week online behavioral weight loss program compared to usual care to promote weight loss in the postpartum period among women with cardiovascular risk…
- Conditions
- Weight Loss, Postpartum Weight Retention, Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
- Trial name
- EMPOWER-Mom (NCT04914819)
- Testing
- Online Behavioral Weight Loss Program, Virtual weigh-in
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Pennsylvania