Clinical trials: Pre Eclampsia
Medication Adherence, Preeclampsia
Adherence to Universal Aspirin Compared to Screening Indicated Aspirin for Prevention of Preeclampsia
There are data showing that a majority of pregnant women may not be accurately identified as high risk through screening and therefore, not receiving prophylactic low dose aspirin as recommended.
- Trial name
- NCT04797949
- Testing
- Low-dose aspirin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Preeclampsia
Efficacy and Safety of L Arginine to Prevent Preeclampsia
Randomized double-blind controled clinical trial to assess the efficacy and safety of L-arginine to prevent preeclampsia. applied to pregnant women with risk factors for preeclampsia.
- Trial name
- NCT02363348
- Testing
- L arginine
- Where
- Mexico
- Volunteers
- 96 people
- Sponsor
- Hospital Civil Juan I. Menchaca
Preeclampsia Severe, Preeclampsia Postpartum
Biomarkers in Management of Post Partum Preeclampsia
Participants are recruited for a research study about how lab values change following delivery in people with Preeclampsia with Severe Features.
- Trial name
- NCT07478055
- Testing
- Magnesium Sulfate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alexander Harrison
Preeclampsia, Pregnancy Induced Hypertension
Preeclampsia: A Marker for Future Cardiovascular Risk in Women
This study will compare blood vessel and hormone differences between women who have a history of a pregnancy complicated by preeclampsia or high blood pressure, and women who have a history of uncomplicated pregnancy in the last…
- Trial name
- NCT01519297
- Testing
- Irbesartan
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Adverse Pregnancy Outcomes, Cardiovascular Diseases
A Randomized Trial to Reduce Blood Pressure at One Year Postpartum After Preeclampsia
GESTA-COR is a prospective, randomized clinical trial designed to evaluate whether an early, personalized cardiovascular prevention strategy can achieve a clinically meaningful 6 mmHg reduction in systolic blood pressure at one…
- Trial name
- GESTA-COR (NCT06798649)
- Testing
- The intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs).
- Volunteers
- 150 people
- Sponsor
- Maternal-Infantil Vall d´Hebron Hospital
Preeclampsia, Maternal Deaths
The Project of Gestational Hypertension and Preeclampsia Screening and Prevention Center
Preeclampsia is the main cause of illness and death in pregnant women and fetuses. Currently, there is no effective treatment for preeclampsia in clinical practice, and the fundamental treatment is still termination of pregnancy…
- Trial name
- NCT06383858
- Testing
- Screening method
- Where
- China
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Preterm Birth, Low Birth Weight
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital.
- Conditions
- Preterm Birth, Low Birth Weight, Intrauterine Growth Restriction (IUGR), Perinatal Asphyxia
- Trial name
- UCE (NCT06653374)
- Testing
- Infant, Premature
- Where
- Ecuador
- Volunteers
- 26,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Preeclampsia
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9
Preeclampsia is a pregnancy related disease characterized by the new onset of hypertension and proteinuria after 20 weeks of gestation in previously normotensive women.
- Trial name
- NCT03258125
- Testing
- real time PCR (rPCR)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preeclampsia
Consumption of Chocolate in Pregnant Women.
The purpose of this study is to investigate the acute and chronic effect of consumption of flavanol-rich chocolate on endothelium function in pregnant women at high risk for preeclampsia.
- Trial name
- CHOCENTA (NCT01431443)
- Testing
- Flavanol-rich chocolate
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Laval University
Adolescent Pregnancy, Preeclampsia and Eclampsia
Blood Pressure in Adolescents With PReclampsia and Eclampsia.
Levels of blood pressure in adolescents with preeclampsia and eclampsia: Multicenter case-control study (Latin America). Maternities in Latin America: Two hospitals in Panama, one hospital in Mexico, one hospital in El Salvador…
- Trial name
- ADPRE (NCT03360240)
- Where
- 8 sites in Bolivia, Colombia and 4 more
- Volunteers
- 1,050 people
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Pre-Eclampsia, Severe, HELLP Syndrome
Immature Platelet Fraction as a Promising Biomarker in Prediction Outcome of HELLP Syndrome
Immature platelet fraction is a non-invasive test of real time thrombopoiesis. High IPF% has been suggested as an indicator of thrombocytopenia due to rapid platelet consumption.
- Conditions
- Pre-Eclampsia, Severe, HELLP Syndrome, Microangiopathy
- Trial name
- NCT03232359
- Testing
- immature platelets fraction
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- AYMAN ABDELKADER MOHAMED ABDELKADER
Severe Pre-eclampsia, Eclampsia
Comparison of Loading Dose Magnesium Sulphate With Prichard Regimen in the Management of Severe Preeclampsia and Eclampsia.
Preeclampsia/eclampsia is part of a spectrum of multi-systemic pregnancy disorder that contributes substantially to maternal and perinatal morbidity and mortality, especially in low resource setting.
- Trial name
- NCT06126068
- Testing
- Use of magnesium sulfate to prevent and stop fits in pre-eclampsia and Eclampsia
- Where
- Nigeria
- Volunteers
- 120 people
- Sponsor
- Federal Teaching Hospital Abakaliki
Hypertension, Hypertension, Pregnancy-Induced
The Relaxation and Blood Pressure in Pregnancy (REBIP) Study
Over 10% of women have high blood pressure during their pregnancy which may affect their health or that of their baby. There are currently no methods to prevent most high blood pressure in pregnancy and some treatments are not…
- Conditions
- Hypertension, Hypertension, Pregnancy-Induced, Pre-Eclampsia
- Trial name
- NCT00303173
- Testing
- Guided Imagery
- Where
- 2 sites in Canada
- Volunteers
- 69 people
- Sponsor
- University of Toronto
Pre-Eclampsia, Pre-Term
Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Women who had an adverse pregnancy outcome (APO), such as preeclampsia, preterm birth, or gestational diabetes, have a higher risk for heart disease.
- Conditions
- Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
- Trial name
- VIA (NCT04633551)
- Testing
- Anti-inflammatory supplement
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Apnea, Obstructive Sleep, Pregnancy Complications
Sleep Apnea Syndrome in Obese Women During Pregnancy
Excess weight or obesity is associated with an increased risk of health disorders: high blood pressure, diabetes, cardiovascular risks, dyslipidemia and sleep apneas.
- Conditions
- Apnea, Obstructive Sleep, Pregnancy Complications, Pre-Eclampsia, Obesity
- Trial name
- NCT03509805
- Testing
- polysomnography
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Preeclampsia
Calcium Supplementation to Prevent Preeclampsia in Sichuan Province of China
the purpose of this study is to determine whether calcium supplementation is effective to prevent preeclampsia in Sichuang Province of china and which dose is more suitable
- Trial name
- NCT01806454
- Testing
- calcium
- Where
- China
- Volunteers
- 11,000 people
- Sponsor
- West China Second University Hospital
Preeclampsia Severe
Intravenous Labetalol Versus Hydralazine in Preeclampsia
We study the effect of intravenous labetalol versus hydralazine in sever preeclampsia patients on cerebral blood flow and neurological outcome
- Trial name
- NCT06360601
- Testing
- Labetalol Injection, HydrALAZINE Injection
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Pre-Eclampsia, Gestational Hypertension
Physician Optimised Post-partum Hypertension Treatment Trial
It has been shown in a pilot randomised controlled study [SNAP-HT [4]; REC 14/SC/1316] that blood pressure self-management during the post-partum period after hypertensive pregnancies, results in lower blood pressure after six…
- Trial name
- POP-HT (NCT04273854)
- Testing
- OMRON Evolv® blood pressure monitor (Blue-tooth® enabled) & Proprietary Smartphone POP-HT app®
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Oxford
Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml, Preeclampsia
Vitamin D and Preeclampsia
Hypothesis : Vitamin D serum concentration is decreased in the first trimester in pregnant women who will develop preeclampsia in the second or third trimester compare to a control group Primary purpose : To determine the vitamin…
- Conditions
- Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml, Preeclampsia, Neonatal Hypercalcemia, Pregnancy
- Trial name
- FEPED (NCT01648842)
- Where
- France
- Volunteers
- 3,173 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris