Clinical trials: Pre Eclampsia
Pre-Eclampsia
Prenatal Yoga as Complementary Therapy of Preeclampsia
Preeclampsia is a specific pregnancy disorder that complicates approximately 3-5% of all pregnancies. The effects on pregnant women vary from mild hypertension, severe hypertension / hypertensive crisis, eclampsia to hemolysis…
- Trial name
- NCT04795154
- Testing
- Yoga excercise
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Preeclampsia Severe
Uterotonics for Severe Preeclampsia
The study compares the effect of Intravenous carbetocin versus combined use of intravenous oxytocin and rectal misoprostol for prevention of postpartum hemorrhage during delivery of women with severe preeclampsia
- Trial name
- NCT04756661
- Testing
- Carbetocin, Oxytocin, Misoprostol
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Assiut University
Preeclampsia
Pravastatin for Prevention of Preeclampsia
The primary purpose of this pilot study is to determine the pharmacokinetic (PK) parameters and collect preliminary safety data for pravastatin when used as a prophylactic daily treatment in pregnant women at high risk of…
- Trial name
- Statin (NCT01717586)
- Testing
- Pravastatin
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Preeclampsia, Intrauterine Growth Restriction
Fetal, Obstetrics and Reproduction Genomics
The purpose of this study is to determine the impact of a clinical screening strategy and genomic analysis of the factors involved in Placental Dysfunction (Preeclampsia and IUGR) in women of advanced maternal age undergoing…
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Placental Disease
- Trial name
- FORgenomics (NCT05720169)
- Testing
- Doppler ultrasound, Blood sample
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fundación Ginemed
Antiphospholipid Antibody Syndrome in Pregnancy
Obstetric Antiphospholipid Antibody Syndrome : Contribution of the Evaluation of ADAMTS13 Made at the Diagnosis of Pregnancy on Evaluation the Risk of Pre-eclampsia
Study based on data concerning the first pregnancy treated and followed up after the diagnosis of oAPS in the NOH-APS cohort, according to clinical results already published; and on a thematic library collected and preserved at…
- Trial name
- NOH-ADAMTS (NCT04319341)
- Testing
- To study the prognostic value on the occurrence of pre-eclampsia, ADAMTS13 (ADAMTS13 protein and autoantibodies) in patients diagnosed with oAPS
- Where
- France
- Volunteers
- 513 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Severe Pre-eclampsia, Postpartum Condition or Complication
Prevention of Postpartum Hemorrhage in Patients With Severe Preeclampsia Using Carbetocin Versus Misoprostol
We aim to compare carbetocin with misoprostol for the prevention of postpartum hemorrhage in patients with severe preeclampsia. The primary outcome is postpartum haemorrhage (blood loss of ≥ 500 ml) while our Secondary outcomes…
- Trial name
- carbetocin (NCT02086994)
- Testing
- misoprostol, carbetocin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- khalid abd aziz mohamed
Preterm Preeclampsia
Efficacy of Sildenafil in Preterm Preeclampsia
Randomized controlled trial to assess efficacy of Sildenafil in addition to expectant management for the treatment of preterm preeclampsia
- Trial name
- SIL (NCT02782559)
- Testing
- Sildenafil
- Sponsor
- The University of Texas Health Science Center, Houston
Preeclampsia, Gestational Diabetes Mellitus (GDM)
Cardiometabolic Disease and Substrate Metabolism
This study's primary purpose is to determine the potential relationship between cardiometabolic disease, specifically insulin resistance (HOMA-IR), and maternal lipid oxidation.
- Conditions
- Preeclampsia, Gestational Diabetes Mellitus (GDM), Preeclampsia (PE), Preeclampsia (PE) Risk
- Trial name
- CAP (NCT07565727)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Preeclampsia
Ibuprofen vs Dipyrone After C-section in Preeclampsia
The goal of this randomized, triple-masked clinical trial is to compare the effectiveness and safety of the use of ibuprofen versus dipyrone for postoperative analgesia in postpartum women with preeclampsia undergoing cesarean…
- Trial name
- DIPROFEN (NCT05586373)
- Testing
- medication 1, medication 2
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Preeclampsia, Postpartum Period
The PreEclampsia Postpartum Prevention Trial
The goal of this clinical trial is to learn if a postpartum bundle intervention can improve cardiometabolic health and lifestyle-related factors in women who have had preeclampsia during their first pregnancy.
- Conditions
- Preeclampsia, Postpartum Period, Hypertension, Cardiovascular Diseases
- Trial name
- PEPP (NCT07199283)
- Testing
- Bundle Intervention
- Where
- 2 sites in Sweden
- Volunteers
- 356 people
- Sponsor
- Karolinska Institutet
Preeclampsia
Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy
The MINDBP study will enroll 90 pregnant women at risk for HDP across two sites (MCW and Brown) and randomize them to: (1) mindfulness training (MT) plus wearable biosensors, (2) MT alone, or (3) routine prenatal care.
- Trial name
- MINDBP (NCT07218237)
- Testing
- Mindfulness training, Garmin Vivoactive 4 watch
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Medical College of Wisconsin
Pre-Eclampsia
Vital Mechanism of NETs Formation vs. Suicidal Mechanism of NETs Formation During Normal Pregnancy and Preeclampsia
Formation of neutrophil extracellular traps (NETs) is a process of activation of neutrophils, which then generate filaments containing DNA, enzymes and extracellular histones.
- Trial name
- GrossNETs (NCT05470712)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hypertension, Pregnancy-Induced
Hypertension In Postpartum Preeclampsia Study
This study aims to evaluate whether NSAIDs (Non-steroidal antiinflammatory drugs) administered during the postpartum period influence blood pressure in women with hypertensive disorders of pregnancy.
- Trial name
- HIPPS (NCT03011567)
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- MemorialCare Health System
Pre-eclampsia
Thoracic Ultrasonography for Pulmonary Edema in Patients With Pre-Eclampsia
This project will study the use of ultrasound of the chest for the detection of fluid in the lungs in patients with pre-eclampsia vs pregnant patients without pre-eclampsia.
- Trial name
- NCT02357264
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Preeclampsia
Screening for Preeclampsia With Various Markers in Low-risk Pregnancy Populations
For the prediction of late-onset preeclampsia (PE) in low risk women, the investigators established a cut-off value for sFlt-1/PlGF ratio and evaluated the combination models of Elecys, second trimester uterine artery (UtA)…
- Trial name
- NCT01649128
- Volunteers
- 262 people
- Sponsor
- CHA University
Cardiovascular Biomarkers, Preeclampsia (PE) Risk
A Study to Find and Confirm Blood-based Markers (Called Proteins) That May Show Early Heart Changes in Women With Preeclampsia, Even Before Symptoms Appear, and the Use of Heart Ultrasound (Echocardiography) to Look at Patterns of How the Heart Changes During Pregnancy in Women With Preeclampsia
The goal of this study is to find and confirm blood-based markers (called proteins) that may show early heart changes in women with preeclampsia, even before symptoms appear.
- Conditions
- Cardiovascular Biomarkers, Preeclampsia (PE) Risk, Preeclampsia (PE)
- Trial name
- PRECISE (NCT07463898)
- Testing
- No Intervention: Observational Cohort
- Where
- Nigeria
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hemodynamic Instability
Prophylactic Norepinephrine and Phenylephrine Infusion for Hemodynamic Effects in Patients With Preeclampsia
The purpose of this study is to investigate the maternal cardiac output response to prophylactic norepinephrine and phenylephrine infusion for postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean…
- Trial name
- NCT05035498
- Testing
- Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 72 people
- Sponsor
- General Hospital of Ningxia Medical University
Preeclampsia
Haptoglobin and Preeclampsia
The purpose of this study is to show that a certain protein called haptoglobin protects against preeclampsia which is a common pregnancy complication.
- Trial name
- NCT01027130
- Where
- Israel
- Sponsor
- Bnai Zion Medical Center
Pre-Eclampsia
The Effectiveness of Aspirin on Preventing Pre-eclampsia
This study will explore the effectiveness of low-dose aspirin on preventing pre-eclampsia in high-risks pregnant women by comparing the incidence of pre-eclampsia and pregnancy outcomes.
- Trial name
- NCT04656665
- Testing
- Aspirin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Gestational Diabetes, Gestational Hypertension
Preventing Obstetric Complications With Dietary Intervention
The goal of this study is to learn whether access to healthy and fresh food, health coaching, and nutrition support intervention can reduce adverse birth outcomes in pregnant women.
- Conditions
- Gestational Diabetes, Gestational Hypertension, High Risk Pregnancy, Preeclampsia
- Trial name
- PLATE (NCT06320054)
- Testing
- Maternal Health Management Program
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin