Clinical trials: Pre Eclampsia
Cardiovascular Diseases, Pre-Eclampsia Onset Less Than 37 Weeks (Diagnosis)
Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsia
This is a double blind randomised controlled feasibility study investigating the effect of postnatal enalapril on cardiovascular function in women who have had preterm pre-eclampsia.
- Trial name
- PICk-UP (NCT03466333)
- Testing
- Enalapril Maleate
- Where
- United Kingdom
- Volunteers
- 118 people
- Sponsor
- Manchester University NHS Foundation Trust
Inflammatory Markers, Preeclampsia Severe
Assessment of Maternal and Fetal Serum Biomarkers in Women With Pre-eclampsia
The findings of markers of placental dysfunction in women with preeclampsia may suggest that these biomarkers may be useful tools for early detection of preeclampsia
- Conditions
- Inflammatory Markers, Preeclampsia Severe, Preeclampsia Mild, Umbilical Cord Issue
- Trial name
- NCT06712550
- Where
- Iraq
- Volunteers
- 204 people
- Sponsor
- SHAHLA KAREEM ALALAF
Preeclampsia, Spinal Anesthesia-Induced Hypotension
Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in Preeclampsia
This study compares the efficacy and safety of intravenous dexamethasone versus intravenous ondansetron in preventing low blood pressure (hypotension) following spinal anesthesia in pregnant women with preeclampsia undergoing…
- Conditions
- Preeclampsia, Spinal Anesthesia-Induced Hypotension, Cesarean Section
- Trial name
- NCT07793760
- Testing
- Dexamethasone, Ondansetron
- Volunteers
- 110 people
- Sponsor
- Assiut University
Preeclampsia Severe
Effect of Magnesium Sulphate on the Intracranial Pressure of Preeclamptic Patients
It had been shown that high percentage of severe preeclampsia patients got a high cerebral perfusion pressure (CPP) due to abnormal autoregulation of cerebral blood vessels with associated endothelial dysfunction and disrupted…
- Trial name
- NCT03210350
- Testing
- Optic nerve sheath diameter
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Corniche Hospital
Hypertension
Central Blood Pressure
The aim of the study is to check standard screening blood pressure in the arm and central blood pressure, the blood pressure at the heart in pregnant women.
- Trial name
- NCT03026010
- Testing
- central blood pressure
- Volunteers
- 100 people
- Sponsor
- St. Louis University
Preeclampsia, Hypertension
Study of Positive Airway Pressure in Preeclampsia to Reduce Blood Pressure
The purpose of this study is to identify whether sleep-disordered breathing - as measured by overnight polysomnography - is associated with pre-eclampsia and to determine whether use of positive airway pressure can improve…
- Trial name
- NCT01029691
- Testing
- Positive Airway Pressure
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Michigan
Pre-Eclampsia; Mild
Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
Mild pre-eclampsia represents 75% of cases with pre-eclampsia, possible progression to severe pre-eclampsia makes mild pre-eclampsia a serious problem that requires attention.
- Trial name
- NCT03262961
- Testing
- Sildenafil 20 MG
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Pre-eclampsia
New Magnesium Sulphate Protocol for Pre-eclampsia
there is a standard magnesium sulphate protocol and newer protocols for pre-eclampsia, we need to make a trial to find the best protocol
- Trial name
- NCT01846156
- Testing
- MgSO4
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Cairo University
Preeclampsia, Gestational Hypertension
Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia
his study investigates the effectiveness of three specific biological markers (biomarkers) in the blood-the sFlt-1/PlGF ratio, soluble endoglin (sEng), and osteoprotegerin (OPG)-to better diagnose and monitor preeclampsia.
- Conditions
- Preeclampsia, Gestational Hypertension, Hypertensive Disorders of Pregnancy
- Trial name
- PE-POSS (NCT07349277)
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ammar Jassim Abed
Preeclampsia With Severe Features
Nifedipine Dosing Daily vs Twice a Day for Pre-eclampsia With Severe Features (NOPPI)
The investigators propose a randomized controlled unblinded trial to evaluate rates of optimal blood pressure control between Nifedipine 60mg XL once daily vs.
- Trial name
- NCT05096728
- Testing
- Nifedipine XL
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University
Preeclampsia
Aggressive Versus Expectant Management of Severe Preeclampsia Remote From Term
How best to manage preeclampsia remote from term is controversial because of conflicting maternal and neonatal risks. Gestational age is the most important determinant of neonatal outcome.
- Trial name
- MEXPRE-Latin (NCT01164852)
- Testing
- Delivery
- Where
- 8 sites in Ecuador, Guatemala and 4 more
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Pre-Eclampsia
State of Coagulation in Pre-eclampsia: Comparing Sonoclot Signature Analysis With Conventional and Specific Haemostasis Assays
Detection of the presence or absence of coagulopathy in cases with pre-eclampsia. Investigate the value of global hemostasis studies (Sonoclot signature analysis) in cases of pre-eclampsia and if there a correlation between it…
- Trial name
- NCT05625763
- Testing
- sonoclot signature analysis
- Volunteers
- 55 people
- Sponsor
- Assiut University
Pregnancy Disease, Preeclampsia
Dietary Salicylates and Preeclampsia
Preeclampsia (PE) is an important pregnancy complication and cause of maternal and perinatal mortality and morbidity. The underlying etiology and pathophysiology of preeclampsia is incompletely understood but it involves…
- Conditions
- Pregnancy Disease, Preeclampsia, Diet Habit
- Trial name
- PreSal (NCT06239363)
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Preeclampsia
Preeclampsia Subtypes and Surrogate Markers of CVD Risk
In order to assess surrogate markers of cardiovascular risk in subtypes of preeclampsia, we will conduct a 10-year follow-up study comparing 40 women with a history of early onset preeclampsia; 40 women with a history of late…
- Trial name
- NCT02337049
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Pre-Eclampsia, Hypertension, Pregnancy-Induced
Low Dose Calcium to Prevent Preeclampsia
The purpose of this study is to assess, in pregnant women with calcium-poor diets, what is the effectiveness of low-dose (500 mg/day) calcium supplements associated with an educational intervention, compared to the educational…
- Conditions
- Pre-Eclampsia, Hypertension, Pregnancy-Induced, Dietary Calcium Deficiency
- Trial name
- AMCAL (NCT02338687)
- Testing
- calcium, Educational sessions
- Where
- Brazil
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pregnancy Related, Pregnancy Disease
Fetal Autonomic Nervous sysTem Evaluation
The autonomic nervous system (ANS) is involved in cardiovascular, metabolic and cognitive processes, so its study in the fetus can provide relevant functional diagnostic and prognostic information.
- Conditions
- Pregnancy Related, Pregnancy Disease, Pregnancy Complications, Pre-Eclampsia
- Trial name
- FANTE (NCT06330987)
- Testing
- electrocardiograph
- Where
- Italy
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Preeclampsia, Microbiome
A Multicenter Cohort Study on Maternal and Infant Microecology and New Targets for Pre-eclampsia Screening in China
major objective This multicenter, prospective cohort study aims at evaluating the predictive value of microbiome ,proteomics and serum markers in preeclampsia.
- Trial name
- CALM2001 (NCT05445544)
- Testing
- Observational studies, The diagnosis was preeclampsia
- Where
- 2 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Preeclampsia, Eclampsia
The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
Neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and endothelial dysfunction. In recent years, it has been reported that the individual components of the differential white cell count, specifically the…
- Trial name
- NCT01856387
- Testing
- high neutrophil to lymphocyte ratio, normal neutrophil-to Lymphocyte ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Pre-Eclampsia, Diphtheria, Tetanus and Pertussis Vaccine Reaction
Comparing the Incidence of Preeclampsia Between Pregnant Women Receiving Tdap Vaccinations at Week 28 or at Week 36
Preeclampsia is a significant medical condition occurring in 3-8% of pregnancies and impacts deleteriously both maternal and fetal health.
- Trial name
- NCT04424693
- Testing
- Tdap Vaccine Administration
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Institute of Arthritis Research
Preeclampsia
The Effect of Epidural Anesthesia on the Optic Nerve Sheath Diameter in Preeclampsia
This study aims to assess the effect of epidural anesthesia on the optic nerve sheath diameter in parturients with preeclampsia.
- Trial name
- ONSD (NCT04095832)
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital