Clinical trials: Pre Eclampsia
Adverse Pregnancy Outcomes, Cardiovascular Diseases
A Randomized Trial to Reduce Blood Pressure at One Year Postpartum After Preeclampsia
GESTA-COR is a prospective, randomized clinical trial designed to evaluate whether an early, personalized cardiovascular prevention strategy can achieve a clinically meaningful 6 mmHg reduction in systolic blood pressure at one…
- Trial name
- GESTA-COR (NCT06798649)
- Testing
- The intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs).
- Volunteers
- 150 people
- Sponsor
- Maternal-Infantil Vall d´Hebron Hospital
Pregnancy Related, Pre-Eclampsia
CONNEQT Pulse Validation Study
The purpose of this study is to validate the accuracy of the CONNEQT Pulse blood pressure monitoring system for the measurement of blood pressure as compared to a gold standard, auscultatory sphygmomanometer in a pregnant…
- Conditions
- Pregnancy Related, Pre-Eclampsia, Gestational Hypertension
- Trial name
- NCT06002971
- Testing
- Blood pressure measurement
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Pre-Eclampsia
Vital Mechanism of NETs Formation vs. Suicidal Mechanism of NETs Formation During Normal Pregnancy and Preeclampsia
Formation of neutrophil extracellular traps (NETs) is a process of activation of neutrophils, which then generate filaments containing DNA, enzymes and extracellular histones.
- Trial name
- GrossNETs (NCT05470712)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pre-Eclampsia, IUGR
Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients.
60 pregnant women with singleton living fetus between 34 -38 wks gestation known to have severe hypertension in the current pregnancy were included.
- Trial name
- NCT03515759
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pre-Eclampsia
Restrictive Fluid Therapy in Severe Preeclampsia
Introduction: Pre-eclampsia is a multifactorial syndrome which occurs in hypertension and proteinuria in pregnant women over 20 weeks gestation.
- Trial name
- NCT02214186
- Testing
- Restrictive Fluid Therapy
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Hypertension, Pregnancy-Induced, Hypertension, Essential Hypertension
Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy
Background: 1. Burden: Hypertensive disorders of pregnancy, including preeclampsia, complicate up to 10% of pregnancies worldwide, constituting one of the greatest causes of fetal growth restriction, preterm birth, low birth…
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension, Essential Hypertension, Hypertension; Pre-Eclampsia, Hypertension in Pregnancy
- Trial name
- NCT03858595
- Testing
- Self monitoring of blood pressure using Health Gauge Device and monthly monitoring of weight gain
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Preeclampsia
Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women
Primary outcome 1. to identify biological changes in nulliparous women at high risk for preeclampsia defined by combined screening by Fetal Medicine Foundation (FMF) 2.
- Trial name
- PRERISK (NCT06200571)
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Pre-eclampsia, Pregnancy
Vitamin D for Preventing Recurrent Preeclampsia in Pregnant Women
The goal of this clinical trial is to find out whether giving vitamin D to pregnant women who had pre-eclampsia in a previous pregnancy helps prevent the condition from coming back.
- Conditions
- Pre-eclampsia, Pregnancy, Vitamin D
- Trial name
- NCT07288801
- Testing
- Vitamin D
- Where
- Pakistan
- Volunteers
- 146 people
- Sponsor
- Nishtar Medical University
Preeclampsia, Preterm Delivery
Ambient Air Pollution, Preeclampsia, and Preterm Delivery
An epidemiologic study of pregnant women in western Washington to measure the relationships between exposure to air pollutants and risks of preeclampsia and preterm delivery.
- Trial name
- NCT00468663
- Volunteers
- 4,200 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Preeclampsia
Cardiovascular Risk After Preeclampsia
Investigation of cardiovascular risk 5-15 years after early or late-onset preeclampsia by adenosine stress Magnetic Resonance Imaging and non-invasive methods like retinal vessel analysis, skin measurement of advanced glycation…
- Trial name
- NCT05277233
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Hypertension
Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia
Hypertensive disorders of pregnancy are a major cause of maternal mortality and morbidity, especially in developing countries. Postpartum hypertension can be related to persistence of gestational hypertension, preeclampsia, or…
- Trial name
- NCT01988298
- Testing
- Ibuprofen, Acetaminophen
- Where
- Panama
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Pregnancy Induced Hypertension, Preeclampsia and Eclampsia
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
The target population for our study is healthy nulliparous pregnant women (first pregnancy) between the 12-16 week of pregnancy. If a subject is eligible, written consent will be obtained by person to person contact.
- Conditions
- Pregnancy Induced Hypertension, Preeclampsia and Eclampsia, Gestational Hypertension
- Trial name
- NCT04979793
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Preeclampsia
Novel Biomarkers of Preeclampsia, Aquaporin, Fatty Acid, and S110B
This is a research study designed to help identify preeclampsia in pregnant women earlier, and possibly lead to better treatment for women preeclampsia.
- Trial name
- NCT03567551
- Testing
- Women w/ Preeclampsia w/o Visual Disturbances or Headache, Women w/ Preeclampsia w/ Visual Disturbances or Headaches, Women w/o Preeclampsia
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pregnancy Related, Diet Modification
Effects of Diet on Pregnancy Outcome and Child Obesity
The purpose of the study is to compare 3 different diets in pregnancy, equal in calories, and fats, different in refined grains compared to whole grains as a source of carbohydrates, and in calories from carbohydrate, compared to…
- Conditions
- Pregnancy Related, Diet Modification, Obesity, Hypertension
- Trial name
- NCT03232762
- Testing
- Refined Grains, Whole Grains
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pre-Eclampsia
Prediction of Preeclampsia by Comprehensive Markers.
Preeclampsia is one of the most serious complications in pregnancy that causes maternal death and preterm delivery. Series studies has show that the competing risk model developed by the Fetal Maternal FouNdation in early…
- Trial name
- NCT03665623
- Where
- China
- Volunteers
- 11,741 people
- Sponsor
- Peking Union Medical College Hospital
Pre-Eclampsia
Association Between Pococyturia and Pre-eclampsia Severity
Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity.
- Trial name
- PEPOD2 (NCT03316391)
- Testing
- Dosage of urinary podocyturia
- Where
- 2 sites in France
- Volunteers
- 14 people
- Sponsor
- Hospices Civils de Lyon
Preeclampsia, Chronic Periodontitis
microRNA 155 Levels and Periodontal Microflora (Bacteria and Virus) in Preeclampsia.
Preeclamptic women with and without chronic periodontitis were recruited for the study. Subgingival plaque samples and placental tissue samples(postpartum) were obtained from the participants for the microbial analysis(bacteria…
- Trial name
- NCT04277390
- Testing
- clinical intervention for microbial analysis and MIR155 as biomarker
- Where
- India
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Pregnancy, Preeclampsia
The Involvement of Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Placental Implantation and in the Pathological Pregnancies: Preeclampsia and IUGR
The involvement of eukaryotic translation initiation factor 4E (eIF4E) in human placental implantation and in the pathological pregnancies: preeclampsia and IUGR.
- Trial name
- NCT01179542
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center