Clinical trials: Pre-Diabetic
Pre Diabetic
Xinqiao High-risk Cohort of Diabetes(NICE)
Objective: 1. To systematically screen the high-risk population of diabetes in Xinqiao area, understand the characteristics of early glucose metabolism changes and pancreatic islet function changes in the high-risk population and…
- Trial name
- NCT07281170
- Where
- 2 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Shanghai General Hospital, China
Diabetes, Pre-diabetes
Northern Manhattan Study of Metabolism and Mind
Pre-diabetes, type 2 diabetes, and their related conditions, adiposity and insulin resistance, are more prevalent in minorities Northern Manhattan compared to the general population of the United States.
- Conditions
- Diabetes, Pre-diabetes, Cognition - Other, Depressive Symptoms
- Trial name
- NOMEM (NCT02470260)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diabetes Mellitus, PreDiabetes
Effects of Physical Activity in Patients With Diabetes
The primary aim of our study is to evaluate the effects of physical activity counseling and pilates exercises on metabolic control variables in patients with prediabetes and type 2 diabetes; Its secondary aim is to examine the…
- Trial name
- NCT04643873
- Testing
- physical activity counseiling +pilates exercise group, physical activity counseiling group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University - Cerrahpasa
Endometrial Cancer
Study of Insulin Resistance and Endometrial Cancer in Harris County, Texas
The goal of this clinical research study is to find out if there is a link between insulin resistance (or pre-diabetes) and endometrial cancer. Primary Objective: 1.
- Trial name
- NCT00495235
- Testing
- Questionnaire
- Where
- 8 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prediabetes or Overweight
Whole Food Fibers for Support of Key Gut Bacteria for Human Health
The purpose of this supplementation study is to understand how whole food fibers may affect gut microbiota composition and overall health. The investigators will enroll up to 24 people in this study.
- Trial name
- NCT07840170
- Testing
- Whole food fiber mixture, inulin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Purdue University
PreDiabetes
Augmented Care at Worksite for Diabetes Prevention
The purpose of the study was to evaluate the impact of augmented care at the worksite through a lifestyle intervention for diabetes prevention among employees with prediabetes who were slower to respond to a standard diabetes…
- Trial name
- NCT03382873
- Testing
- Group Lifestyle Balance (GLB), Group Lifestyle Balance Plus (GLB+)
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Ohio State University
Prediabetes
Establishing a Virtual Health Community Management Model for Pre-Diabetes Patients
This study builds upon the previously developed virtual health community platform, aiming to address the group characteristics and psychological traits of prediabetic patients.
- Trial name
- NCT07354997
- Testing
- Pre-diabetes Virtual Community
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Prediabetic State, Obesity
Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes
We, the investigators at National Taiwan University Hospital, want to compare patients' islet cell function, insulin sensitivity and risk of chronic complications with normal subjects.
- Conditions
- Prediabetic State, Obesity, Metabolic Syndrome X
- Trial name
- NCT00172796
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Overweight, Obesity
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic and increasing burden of…
- Conditions
- Overweight, Obesity, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT01608620
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Obesity
Identification of Muscle-specific Biomarkers of Fatty Acid Beta-oxidation
Elevated fat levels within skeletal muscle cells (intramyocellular lipids) are highly correlated with muscle and whole-body insulin resistance, and more prevalent in obesity.
- Trial name
- FL-68 (NCT01494025)
- Testing
- Diet and Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Obesity, Insulin Resistance
Vitamin K and Glucose Metabolism in Children at Risk for Diabetes (Vita-K 'n' Kids Study)
The undercarboxylated fractions of the two vitamin K-dependent proteins osteocalcin and matrix Gla protein have been shown to play key roles in type 2 diabetes and cardiovascular disease (at least in mouse models).
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Prediabetes
- Trial name
- NCT01972113
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45 mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Diabetes
Relation of White Blood Cell Function to Diabetes
Background: Patients who are pre-diabetic or have adult onset (type 2) diabetes have a significantly greater risk of developing heart, blood vessel, or kidney diseases.
- Trial name
- NCT00570154
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Prediabetic State, Obesity
The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes
The overall objective is to compare the short-term (3 months) effectiveness of three glucose-lowering interventions (dapagliflozin, metformin and physical activity) on glucose variability, body composition, and cardiometabolic…
- Trial name
- NCT02695810
- Testing
- Dapagliflozin, Metformin, Exercise
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Overweight, Obesity
Effect of Dietary Habits on Metabolic Health
The goal of this application is to understand the connection between people's eating habits and the risk for developing diabetes, obesity, and cardiovascular disease.
- Conditions
- Overweight, Obesity, Prediabetes, Meals
- Trial name
- NCT02298790
- Testing
- Meal schedule
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
PreDiabetes, Obesity
Effect of Nutritional Supplements on Clinical Outcomes in Patients With Prediabetes and Obesity
This study aims to improve blood glucose and weight in patients with prediabetes and obesity through health education, nutritional supplement interventions, clinical evaluation, and close clinical follow-up.100 patients with…
- Trial name
- NCT05273840
- Testing
- Ivital Control, lifestyle intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ningbo No. 1 Hospital
PreDiabetes
Effects of Exercise Based Manual in Sedentary Prediabetic Population
The prediabetes is a state in which fasting blood glucose level ranges between 100-126mg/dl or HbA1C ranges between 5.7-6.4mmol. People with prediabetes have 74 percent chance of progression to develop Type 2 diabetes mellitus.
- Trial name
- NCT04949958
- Testing
- Exercise Based Manual (Supervised), Exercise Based Manual (Home Based), Control
- Where
- Pakistan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Diabetes Mellitus
Improving Physical Activity Levels in the Arabic- Speaking Residents of East Jerusalem With Prediabetes
This three-arm clinical trial aims to improve levels of physical activity among Arabic- speaking residents of East Jerusalem with prediabetes.
- Trial name
- NCT03821220
- Testing
- Motivational Interview support and Dietitian support, Activity tracker plus usual care, Personalized physical activity prescription
- Volunteers
- 375 people
- Sponsor
- Clalit Health Services
Elevated Blood Sugar
Power of Choice on Autonomy, Motivation, Exercise Adherence, and Cardiorespiratory Fitness
People with elevated blood sugar levels are at increased risk of developing chronic medical conditions such as obesity, type 2 diabetes, and cardiovascular disease.
- Trial name
- NCT03576924
- Testing
- MICT, HIIT, CHOICE
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Insulin Resistance, Impaired Glucose Tolerance
Cassia Cinnamon for Glucose Uptake in Young Women
The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and 5g of cellulose placebo on blood…
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, Prediabetes
- Trial name
- NCT00951639
- Testing
- Cassia cinnamon, 50 minutes exercise, Cellulose Powder
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baylor University
Pre Diabetes, Insulin Resistant
Beneficial Effect of Salicylates: Insulin Action, Secretion or Clearance?
The possibility that obesity-associated inflammatory changes may play a role in the pathogenesis of type 2 diabetes (2DM) has led to increased interest in the possibility that salicylates might represent a useful treatment to…
- Trial name
- NCT02007577
- Testing
- salsalate
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Stanford University