Clinical trials: Pre-ESRD
Chronic Kidney Disease, Chronic Kidney Disease Requiring Chronic Dialysis
Breaking Down Care Process and Patient-level Barriers to Arteriovenous Access Creation Prior to Hemodialysis Initiation
More than 80% of individuals in the U.S. start maintenance hemodialysis (HD) with a central venous catheter, despite substantial evidence that starting HD with an arteriovenous (AV) access improves quality of life, lowers…
- Trial name
- NCT04032613
- Testing
- Vascular Access Navigation and Education Quality Improvement Program
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Kidney Injury, Acute Kidney Failure
Q10 Preloading Before Cardiac Surgery for Kidney Failure Reduction
Coenzyme Q10 (CoQ10) is an essential molecule in human body. It acts as an antioxidant, a co-factor for energy conversion in mitochondria and has anti-inflammatory effects capable of improving endothelial function.
- Trial name
- PREKARKID-10 (NCT04445779)
- Testing
- Coenzyme Q10
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Clinical Hospital Center, Split
Chronic Kidney Disease, Obstructive Sleep Apnea
Central and Peripheral 24-h Blood Pressure Before and After 3 Month of CPAP Treatment in Obstructive Sleep Apnea
The purpose of this study is to investigate the effect of 3 months of continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA) in moderate to severe cases in patients with chronic kidney disease.
- Trial name
- NOSI (NCT01951248)
- Testing
- CPAP - continuous airway pressure
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Erling Bjerregaard Pedersen
Arterio-venous Fistula, Kidney Failure
Prefistula Forearm Exercise in Pts Requiring Chronic HD Therapy
For chronic hemodialysis patients, the creation of a well-functioning arteriovenous (AV) fistula is critical for ensuring that patient receive adequate hemodialysis.
- Conditions
- Arterio-venous Fistula, Kidney Failure, Hemodialysis Access Failure
- Trial name
- NCT03988270
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Hepatitis C, End Stage Renal Disease
A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD)
1. A maximally tolerated dose of ribavirin can be defined in each patient with ESRD undergoing hemodialysis. 2. Patients with Chronic Hepatitis C Virus (HCV)and End-Stage Renal Disease (ESRD)undergoing hemodialysis will be able…
- Trial name
- NCT01731301
- Testing
- Ribavirin, Peginterferon, Boceprevir
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Liver Institute of Virginia
Renal Insufficiency, Diabetes Mellitus
Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography
It is well known that X-ray contrast media can affect kidney function in some patients, especially when administered intra-arterially, and patients who already suffer from reduced kidney function and diabetes mellitus may be at…
- Trial name
- NCT00209417
- Testing
- Iodixanol 320-Arm 1, Iopamidol 300-Arm 2
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 656 people
- Sponsor
- GE Healthcare
Acute Kidney Injury
Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass graft (CABG) surgery, and often requires patients to go on dialysis.
- Trial name
- NCT03810417
- Testing
- Digoxin Antibodies Fab Fragments, Baseline EO > 360 pM, EO < 360 pM
- Where
- 2 sites in United States
- Volunteers
- 267 people
- Sponsor
- University of Maryland, Baltimore
Anemia, Kidney Failure
Dynepo Infrequent Dosing Study
The purpose of this study is to demonstrate non-inferiority of efficacy between twice weekly and once weekly dose schedule of Dynepo in previously erythropoietin (EPO)-naive patients, as measured by haemoglobin at week 24 and…
- Trial name
- NCT00450333
- Testing
- Dynepo (Epoetin delta), Dynepo
- Where
- 53 sites in Austria, Belgium and 5 more
- Volunteers
- 407 people
- Sponsor
- Shire
Preeclampsia
Ibuprofen vs Dipyrone After C-section in Preeclampsia
The goal of this randomized, triple-masked clinical trial is to compare the effectiveness and safety of the use of ibuprofen versus dipyrone for postoperative analgesia in postpartum women with preeclampsia undergoing cesarean…
- Trial name
- DIPROFEN (NCT05586373)
- Testing
- medication 1, medication 2
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Acute Kidney Injury, Cardiac
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery: a Retrospective Monocentric Cohort Study
Cardiac surgery with cardiopulmonary bypass exposes patients to the risk of post-operative acute kidney injury. In the specific setting of cardiac surgery, acute kidney injury is often of multifactorial origindue to particular…
- Conditions
- Acute Kidney Injury, Cardiac, Surgery
- Trial name
- SGLT2i (NCT06453161)
- Testing
- Post-operative acute kidney injury
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon