Clinical trials: Pre-Eclampsia; Complicating Pregnancy
Preeclampsia
Assessing the Usability and Clinical Utility of the Congo Red Dot Test: A Survey
To determine if women can understand the instructions, carry out the test, and interpret the test results. Women will be recruited to complete a test instruction and comprehension assessment and a usability assessment.
- Trial name
- NCT02611011
- Testing
- Congo Red Test (GV-005)
- Where
- Mexico
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pre-Eclampsia Onset Less Than 37 Weeks, Pre-Eclampsia
Preeclampsia Intervention Netherlands
The goal of this study is to find out if pregnant individuals with preterm preeclampsia (PE) who are treated with metformin can stay pregnant for longer, and if this is safe(r) for the mother and child.
- Conditions
- Pre-Eclampsia Onset Less Than 37 Weeks, Pre-Eclampsia, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia as Antepartum Condition
- Trial name
- PI-NL (NCT06452498)
- Testing
- Metformin Hydrochloride
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Amsterdam UMC
Pre-Eclampsia, Hyperuricemia
Xanthine Oxidase and Uric Acid Origin in Preeclamptic Women
Findings regarding the presence of xanthine oxidase and uric acid in different blood locations is important in preeclamptic women.
- Trial name
- NCT04463940
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Barzilai Medical Center
Preeclampsia, Maternal
A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women
Primary Endpoint: Quantify the hemodynamic changes in preeclampsia using the non-invasive Nexfin device. Secondary Endpoint: Determine if measurable hemodynamic changes are statistically correlated with B-type natriuretic peptide…
- Conditions
- Preeclampsia, Maternal, Hypertension, Pregnancy
- Trial name
- NCT02527018
- Testing
- Sphygmomanometer
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Preeclampsia
Comparison of Pregnancy Outcomes in Primigravida Receiving Low-Dose Aspirin for the Prevention of Preeclampsia.
Local data on the effectiveness of low-dose aspirin in high-risk primigravida are limited. The present study was planned to compare pregnancy outcomes between high-risk primigravida receiving low-dose aspirin (75 mg/day) from 12…
- Trial name
- NCT07852585
- Testing
- Low-dose aspirin, No-Aspirin
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- Muhammad Aamir Latif
Pre-Eclampsia
Classical Turkish Music for Pregnant Women With Preeclampsia
Stress and Sleep of Classical Turkish Music in Pregnant Women Diagnosed with Preeclampsia in Clinics The study to be carried out to determine the effect on quality is a randomized controlled experimental research.
- Trial name
- NCT06315985
- Testing
- Experimental group: Listenning to the Turkish Classical Music to pregnant women diagnosed with preeclampsia
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Pre-Eclampsia, Pre-Term
Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Women who had an adverse pregnancy outcome (APO), such as preeclampsia, preterm birth, or gestational diabetes, have a higher risk for heart disease.
- Conditions
- Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
- Trial name
- VIA (NCT04633551)
- Testing
- Anti-inflammatory supplement
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Pre-Eclampsia, Frozen Embryo Transfer
Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer
Identifying modifiable factors that contribute to preeclampsia risk associated with assisted reproduction can improve maternal health.
- Trial name
- PREECLAM-2019 (NCT04092829)
- Testing
- FROZEN EMBRYO TRANSFER IN SUBSTITUTED CYCLE
- Where
- Spain
- Volunteers
- 591 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Preeclampsia
Physical Therapy in Pregnant Women With Preeclampsia
The aim of this study is to evaluate the influence that has a physical therapy protocol in maternal and fetal hemodynamics in relation to blood pressure, maternal and fetal responses and perinatal outcomes.
- Trial name
- FPE (NCT01630772)
- Testing
- Physical therapy, No physical therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Preeclampsia, CAS
Preeclampsia and Contact Activation
Preeclampsia (PE) affects approximately 5% of all pregnancies with 2,500 cases registered annually in Denmark. PE is characterized by incomplete modelling of the spiral arteries of the uterus, hypertension, inflammation…
- Conditions
- Preeclampsia, CAS, Misfolding Disease, Protein
- Trial name
- NCT04825145
- Testing
- Pregnancy
- Where
- Denmark
- Volunteers
- 234 people
- Sponsor
- University of Southern Denmark
Pre-Eclampsia
Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia
This study aims to compare between androgens level (serum total and free testosterone) in women with preeclampsia and normal ones in the third trimester of pregnancy (28-40 weeks).
- Trial name
- NCT02992145
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams Maternity Hospital
Premature Birth, Pre-Eclampsia
Select Nutrient and Gene Variant Analysis in a Targeted Diet and Lifestyle Intervention Reduces Preterm Birth
Preterm birth (PTB) rates in the US are among the highest in wealthy nations across the globe, and they are particularly high in our most socio-economically disadvantaged populations.
- Conditions
- Premature Birth, Pre-Eclampsia, Small for Gestational Age Infant
- Trial name
- SNGLI-PTB (NCT05436119)
- Testing
- GrowBaby
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- GrowBaby Life Project
Hypertensive Disorder of Pregnancy
Improving Maternal Cardiovascular Outcomes Through the Implementation of a Hypertensive Disorders of Pregnancy Bundle in Nigeria
The goal of this interventional study is to learn from patients and healthcare providers at 4 health institutions (study sites) in Abuja and Kano in Nigeria what ways to best develop the content of a Hypertensive Disorders of…
- Trial name
- IMPACT-HDP (NCT06859359)
- Testing
- Hypertension Disorders of Pregnancy (HDP) Implementation Bundle
- Where
- 4 sites in Nigeria
- Volunteers
- 1,200 people
- Sponsor
- Washington University School of Medicine
Severe Pre-Eclampsia
Serum Magnesium Concentration in Magnesium Sulfate Therapy for Severe Preeclampsia
Pregnant women diagnosed with pre-eclampsia with severe features will be treated with magnesium sulfate to prevent seizures. Magnesium sulfate will be administered according to My Duc Hospital's protocol for treatment of…
- Trial name
- NCT05283473
- Where
- Vietnam
- Volunteers
- 64 people
- Sponsor
- Mỹ Đức Hospital
Preeclampsia
Evaluation of Educational Tools for Pregnant Women
Hypertensive disorders of pregnancy happen in 5% of pregnancies. Being aware of symptoms and complications may help women to present early and preserve their own and their baby's health.
- Trial name
- NCT01858324
- Testing
- Educational tools
- Where
- Canada
- Volunteers
- 247 people
- Sponsor
- Université de Sherbrooke
Preeclampsia
162 mg of Aspirin for Prevention of Preeclampsia
This is a study to assess if 162 mg of aspirin will decrease rates of preeclampsia in pregnant patients compared to 81 mg of aspirin.
- Trial name
- NCT05221164
- Testing
- Aspirin 162 mg
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Methodist Medical Center of Illinois
Preeclampsia
Esomeprazole in Treatment of Early Onset Preeclampsia (ESOPE Trial)
Pre-eclampsia is one of the most serious complications of pregnancy affecting 3-8 % of pregnancies worldwide. It is a multi-system disorder involving maternal vessels (causing hypertension and endothelial dysfunction), the…
- Trial name
- NCT03213639
- Testing
- Esomeprazole 40 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Assiut University
Preeclampsia
Vitamin D Therapy to Prevent Recurrent Preeclampsia in High-Risk Pregnancies
The goal of this clinical trial is to determine whether vitamin D supplementation can reduce the recurrence of preeclampsia in pregnant women with a previous history of preeclampsia.
- Trial name
- NCT07717931
- Testing
- Vitamin D (Cholecalciferol )
- Where
- Pakistan
- Volunteers
- 146 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Pre-eclampsia
Disease Modification in Toxaemia of Pregnancy
Short description of the primary purpose of the protocol intended for the lay public. Include brief statement of study hypothesis Pre-eclampsia (toxemia of pregnancy) is the most cause of death among pregnant women in North…
- Trial name
- NCT00175695
- Testing
- Recombinant human activated protein C or drotrecogin alpha
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Pre-Eclampsia
Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes.
The main objective of this trial is to study the occurrence of preeclampsia in recipients of donated oocytes receiving aspirin at an early stage during pregnancy and to compare the results with those obtained in patients…
- Trial name
- PROVAS (NCT02174328)
- Testing
- Acetylsalicylic acid
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe