Clinical trials: Pre-Term, open to volunteers
Preeclampsia, Preterm Birth
Biobank on Prematurity, Preeclampsia and Other Pregnancy Complications
The Biobank includes data and biological specimens of women from three original studies: 1) First-trimester Prediction of Preeclampsia (PREDICTION Study, NCT02189148), 2) Pre-Eclampsia And growth Retardation, an evaluative…
- Conditions
- Preeclampsia, Preterm Birth, Pregnancy Complications, Fetal Anomalies
- Trial name
- NCT02744365
- Testing
- Observational
- Where
- Canada
- Volunteers
- 7,845 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Respiratory Distress Syndrome, Newborn
"Effectiveness of Delivery Room Bubble CPAP in Preterm Infants With Respiratory Distress
Background When babies are born too early (preterm), their lungs are often not fully developed. They may have trouble breathing because their airways and chest are not strong enough, and their lungs don't make enough surfactant…
- Trial name
- NCT07162285
- Testing
- Delivery Room Bubble CPAP, Delivery Room Supplemental Oxygen
- Where
- Bangladesh
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Very Preterm Infant, Very Low Birthweight
LIFT-UP: Randomized Controlled Trial of Fortification of Human Milk
The goal of the LIFT-UP randomized controlled trial is to evaluate the efficacy of feeding routinely and fortified human milk using a standardized clinical protocol to very low birthweight (VLBW) or very preterm (VPT) infants in…
- Trial name
- LIFT-UP RCT (NCT06765863)
- Testing
- Human Milk Fortifier, Volume targets
- Where
- 4 sites in India
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Environmental Exposure, Pregnancy Related
Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)
The purpose of this project is to reduce maternal environmental exposures to toxicants through a patient education program designed to help pregnant women learn about exposure through consumption of contaminated seafood and to be…
- Conditions
- Environmental Exposure, Pregnancy Related, Preterm Birth, Chronic Respiratory Disease
- Trial name
- PEEPS (NCT07758114)
- Testing
- Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Apnea of Prematurity, Respiratory Insufficiency
Doxapram Therapy in Preterm Infants (DOXA Trial)
Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system.
- Trial name
- NCT04430790
- Testing
- Doxapram
- Where
- 24 sites in Belgium, Canada and 1 more
- Volunteers
- 396 people
- Sponsor
- Erasmus Medical Center
Labor Complication
Intrapartum Ultrasound in Labor: Sonography Only, Few Internal Examinations
This is a prospective, randomized trial to determine whether the use of sonographic parameters during labor results in less intrapartum infection compared to traditional invasive examination.
- Trial name
- SOFIE (NCT06261710)
- Testing
- Sonography in labour
- Where
- Germany
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Larry Hinkson
Bronchopulmonary Dysplasia
Mesenchymal Stem Cells for Prevention of Bronchopulmonary Dysplasia in Infants
The clinical study with UMC119-01 is designed to investigate the safety in patients with bronchopulmonary dysplasia ("BPD"). This will be a dose escalation, open-label, single-center study in infants at high risk for BPD.
- Trial name
- NCT03631420
- Testing
- Human Umbilical Cord Derived-Mesenchymal Stem Cells
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Meridigen Biotech Co., Ltd.
Feeding Difficulties, Sucking Behavior
Premature Infant Oral Motor Intervention vs. Pacifier for Oral Feeding Transition in Preterm Infants
This study compares three approaches to help premature babies learn to feed by mouth: a special mouth exercise program (called PIOMI), using a pacifier, and standard care.
- Conditions
- Feeding Difficulties, Sucking Behavior, Premature
- Trial name
- PIOMI (NCT07460089)
- Testing
- Premature Infant Oral Motor Intervention (PIOMI), Pacifier Use (Non-Nutritive Sucking)
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- University of Baghdad