Clinical trials: PreDiabetes, completed
PreDiabetes, Blood Glucose, High
Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes
This study aims to determine whether the effectiveness of cinnamon spice capsules vs. placebo capsules on glucose tolerance in prediabetic subjects who are overweight or obese.
- Trial name
- CINNII (NCT04342624)
- Testing
- Cinnamon
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pre-diabetes
Evaluation of Video On-Demand Programming to Prevent Type 2 Diabetes in Adults
Over the past 40 years, diabetes has increased dramatically in parallel with rapid increases in obesity.About 90 to 95% of persons with diabetes have type 2 diabetes, which begins when the body becomes resistant to the hormone…
- Trial name
- Project NOT ME (NCT01768546)
- Testing
- Virtual Diabetes Prevention Program, Interactive tracking and problem solving web portal
- Volunteers
- 306 people
- Sponsor
- UnitedHealth Group
Polycystic Ovary Syndrome, Glucose Intolerance
Glucose Metabolism in Different PCOS Phenotypes
In the present study glucose metabolism and ectopic lipids in the liver, heart and muscle were investigated in women with the polycystic ovary syndrome (PCOS) and in healthy control subjects.
- Conditions
- Polycystic Ovary Syndrome, Glucose Intolerance, Liver Fat, Glucose Metabolism Disorders
- Trial name
- NCT03204461
- Testing
- Oral glucose tolerance test (OGTT), 1H-magnetic resonance spectroscopy
- Where
- Austria
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Pre Diabetes
Glucose Tolerance and Prevention of Diabetes Mellitus Type 2 by Polyherbal Formulation
Primary protocol to this study is to develop a natural remedy to prevent diabetes mellitus in pre-diabetic state and elaborate the effectiveness of polyherbal formulation for carrying out Phase-II, III and IV.
- Trial name
- Phase-1 (NCT03884920)
- Testing
- Polyherbal formulation
- Where
- 2 sites in Pakistan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Stable Coronary Artery Disease, Obesity
Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease
Chronic inflammatory activation in fat tissue can be the link between adiposity and an increased risk for atherosclerosis. Aim of the study is to investigate how molecular alterations in fat tissue can be influenced by regular…
- Conditions
- Stable Coronary Artery Disease, Obesity, Impaired Glucose Tolerance
- Trial name
- KFO (NCT00510588)
- Testing
- training, training + metformin, training + glitazon
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Leipzig
Pre-Diabetes
Exercise Dose-Response Effects in Prediabetes
The purpose of the study is to evaluate the effects of different amounts and intensities of aerobic exercise training programs, with and without weight loss, in people who are at risk for diabetes.
- Trial name
- STRRIDE-PD (NCT00962962)
- Testing
- Aerobic Exercise, Exercise and Diet
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Duke University
Pre-diabetes
Anti-hyperglycemic Effect of Short-term Arginyl-fructose Supplementation in Subjects With Pre-diabetes and Newly Diagnosed Type 2 Diabetes: Randomized, Double-blinded, Placebo-controlled Trial.
In this double-blind, placebo-controlled study, subjects with prediabetes and type 2 diabetes were randomly assigned to the placebo control group or the test (Arginyl-fructose: AF) group.
- Trial name
- NCT02285231
- Testing
- Arginyl-fructose
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Prediabetes
Explorative Assessment of Biomarkers in Overweight and Obese Subjects
The rationale for this trial is to apply a simple and minimally strenuous pre-screening approach prior to performing more extensive trial-specific screening and baseline-characterization activities in the resulting pre-selected…
- Trial name
- NCT01910051
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Healthy, Impaired Glucose Tolerance
Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability
The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors…
- Trial name
- NCT05493553
- Testing
- Dietary supplement regimen, Dietary supplement and intermittent fasting regimen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unicity International, Inc.
PreDiabetes
Modified Diabetes Prevention Program in Ecuador
This pilot study will evaluate the use of a modified (cultural and language) adaptation of the National Diabetes Prevention Program in a cohort in Quito Ecuador.
- Trial name
- NCT04835636
- Testing
- Diabetes Prevention Program
- Volunteers
- 33 people
- Sponsor
- Ohio University
Diabetes Type 2, PreDiabetes
Cognitive Functions and BDNF in T2DM and Prediabetes Patients
Clinical and epidemiological studies suggest links between cognitive impairments and Type 2 diabetes (T2DM). The underlying mechanisms and causality in diabetes-related cognitive impairment are largely unknown.
- Conditions
- Diabetes Type 2, PreDiabetes, Cognitive Impairment
- Trial name
- NCT05654727
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Insulin Resistance, Prediabetes
Metformin and Longevity Genes in Prediabetes
Pre-diabetes, a condition characterized by hyperglycaemia, is associated with increased cardiovascular risk and reduced life expectancy, as compared to the general population.
- Conditions
- Insulin Resistance, Prediabetes, Aging, Inflammation
- Trial name
- NCT01765946
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Padova
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Home-Based Tele-Exercise vs. Hospital-Based Exercise Programs in Patients With Prediabetes
This study aims to compare the effects of tele-exercise(TELE) and hospital-based exercise(HBE) on functional capacity (maximum oxygen consumption), glycemic control, quality of life and sleep quality in individuals with…
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Telemedecine
- Trial name
- NCT06895161
- Testing
- Remotely supervised exercise at home or outdoors, Hospital-based exercise program, Phone calls with reinforcement feedback
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Gazi University
Behavior, Health, Pre Diabetes
Developing a Lifestyle Intervention for South Asians
This study aims to test the hypothesis that a culturally tailored lifestyle intervention can improve health behaviors among South Asians with prediabetes and diabetes
- Conditions
- Behavior, Health, Pre Diabetes, Diabetes
- Trial name
- NCT03861546
- Testing
- Healthy lifestyle Shared Medical Appointment (SMA) program
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Diabetic Nephropathies
Nitric Oxide (NO) Activity and Diabetic Nephropathy
Experimental data suggest that oxidative stress and endothelial dysfunction are key players in the pathogenesis of diabetic nephropathy.
- Trial name
- NCT00136188
- Testing
- Folic Acid
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Insulin Resistance
Evaluation of the Impact of a Nutritional Supplement Made of Vegetable Oils in People at Risk of Diabetes
Metabolic and cardiovascular diseases are the first cause of morbidity and mortality throughout the world, including Latin America and Colombia.
- Trial name
- NCT03512665
- Testing
- Full dose supplement, Low dose Supplement, Control Oil
- Where
- Colombia
- Volunteers
- 25 people
- Sponsor
- University of Los Andes, Columbia
Vascular Diseases, Impaired Glucose Tolerance
Effects of Dietary Ingredients on Vascular Function
The main aim of the study is to investigate the effects of dietary ingredients (polyphenols and carotenoids) on vascular function during acute glucose load.
- Trial name
- NCT02158481
- Testing
- A capsule containing both polyphenols and carotenoids
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Unilever R&D
Depression, Impaired Glucose Tolerance
Mood and Insulin Resistance in Adolescents At-Risk for Diabetes
Background: Type 2 diabetes is a chronic disease that puts individuals at risk for serious health problems like heart disease, kidney failure, vision problems, and stroke.
- Trial name
- NCT01425905
- Testing
- The Blues Program, Hey Durham
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
PreDiabetes
Preventing Diabetes
The purpose of this project is to improve the quality of weight management care for patients with pre-diabetes and overweight or obesity.
- Trial name
- PD (NCT05395377)
- Testing
- Registered Dietitian/Nutritionist, Diabetes Prevention Program, Weight Watchers, Reimagined
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Geisinger Clinic
Diabetes Mellitus
Effect of Polyherbal Compound for Control of Blood Sugar in Impaired Glucose Tolerance and Diabetes
The aim of the study is to control blood sugar with Sugar Balance capsules which is the leaves of three herbs: ivy ground (Coccinia indica)-200mg, bougainvillia (Bougainvillea spectabilis)-30mg, Madagascar periwinkle…
- Trial name
- NCT02866539
- Testing
- Polyherbal capsule coccinia, bougainvillea, catharanthus
- Where
- India
- Volunteers
- 122 people
- Sponsor
- Composite Interceptive Med Science