Clinical trials: PreDiabetes, completed
Diabetes, Pre Diabetes
Dance and Diabetes/Prediabetes Self-Management
The Dance for Diabetes program was designed as a community service project for the North Carolina Albert Schweitzer Fellowship. The purpose of this research is to evaluate the effectiveness of the project and its impact on…
- Trial name
- NCT04427982
- Testing
- dance, diabetes education
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Prediabetic State, Overweight
Translating the DPP Into the Community
The Diabetes Prevention Program (DPP) demonstrated that an intensive lifestyle intervention resulting in modest weight loss and increased physical activity can delay or prevent the development of type 2 diabetes in those at…
- Conditions
- Prediabetic State, Overweight, Obesity
- Trial name
- NCT00302042
- Testing
- Brief counseling plus group diabetes prevention in community, Brief Counseling for pre-diabetes alone
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Northwestern University
Metabolic Disturbance, Glucose Intolerance
A Nutrient Cocktail to Protect Against Physical Inactivity
This experiment consists on a 20-day reduction in daily step in free-living active individuals to induce physical inactivity. This will be used to test the efficacy of the anti-oxidant cocktail we aim to test as a new…
- Conditions
- Metabolic Disturbance, Glucose Intolerance, Physical Inactivity, Glucose Metabolism Disorders
- Trial name
- NCT03313869
- Testing
- XXS-2A + Omega-3 + Vitamin E + Selenium, control diet
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
PreDiabetes
Association of β-amyloid 40 and 42 With Prediabetes
Background: Previous epidemiological and animal studies have suggested a strong relationship between prediabetes and Alzheimer's disease.
- Trial name
- NCT05035966
- Testing
- Plasma β-amyloid 40 and 42 concentration
- Volunteers
- 1,442 people, healthy volunteers welcome
- Sponsor
- Liegang Liu
PreDiabetes, Metabolic Syndrome
Women's Lifestyle Balance Study
This pilot study aims to determine whether adding a sleep extension and sleep hygiene intervention to an existing lifestyle improvement program improves its efficacy for weight loss in those at risk for diabetes and…
- Conditions
- PreDiabetes, Metabolic Syndrome, Overweight
- Trial name
- LB (NCT03184337)
- Testing
- CDC's PreventT2 Program, CDC's PreventT2 Program with Added Sleep Content
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, San Francisco
Prediabetes, Obesity & Overweight
Postprandial Glucose Kinetics After Carbohydrate Restriction
The goal of this study is to test whether a low-carbohydrate diet (LCD), comparred with a Mediterranean diet (MED) producing similar weight loss, differentially affects fasting and postprandial glucose metabolism in individuals…
- Conditions
- Prediabetes, Obesity & Overweight, Diet Interventions, Carbohydrate Metabolism
- Trial name
- NCT07802275
- Testing
- Low-carbohydrate diet, Mediterranean Diet
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Pregnancy, Overweight and Obesity
Diabetes Prevention Program Feasibility Study of Breastfeeding
The purpose of this study is to learn about the impact of the Diabetes Prevention Program (DPP) coupled with intensive breastfeeding support to help overweight or obese pregnant women lose weight postpartum, improve their blood…
- Trial name
- NCT04021602
- Testing
- Diabetes Prevention Program, Breastfeeding Education, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Kansas Medical Center
Hypertension, Impaired Glucose Tolerance
Clinical Trial To Evaluate The Effect Of Valsartan On Insulin Sensitivity In Subjects With Impaired Glucose Tolerance
THE PURPOSE OF THIS STUDY IS TO DETERMINE IF 24 WEEKS OF TREATMENT WITH VALSARTAN (80 MG - 320 MG) IMPROVES INSULIN SENSITIVITY IN SUBJECTS WITH HIGHER THAN NORMAL GLUCOSE LEVELS USING A TEST CALLED THE EUGLYCEMIC CLAMP.
- Trial name
- NCT00241072
- Testing
- valsartan
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Novartis
Impaired Glucose Tolerance (IGT)
Postmarketing Clinical Study on AO-128
The purpose of open-label study is to evaluate the efficacy and safety of AO-128 (Voglibose) 0.6 mg/day in patients with impaired glucose tolerance (IGT) who had been non-responsive to diet therapy and exercise therapy, and…
- Trial name
- NCT02287402
- Testing
- AO-128
- Volunteers
- 197 people
- Sponsor
- Takeda
Metabolic Syndrome, Impaired Glucose Tolerance
Evaluation of Low Source of Signal in SCOUT DS
The overall objective of this study is to increase the number of dark skin tone individuals in the data set and evaluate if this increase in dark skin tone data has an impact on the accuracy of the SCOUT DS Diabetes Risk Score…
- Conditions
- Metabolic Syndrome, Impaired Glucose Tolerance, Gestational Diabetes
- Trial name
- LSS (NCT01339637)
- Where
- 5 sites in United States
- Volunteers
- 196 people
- Sponsor
- VeraLight, Inc.
PreDiabetes
Study: Diet and Exercise Study to Improve Brain Blood Flow: Blood Flow Improvement Trial
Project Summary Metabolic syndrome (MetS) is associated with the development of diabetes and cardiovascular disease; however it is also linked with cognitive decline and dementia.
- Trial name
- BFIT (NCT03117829)
- Testing
- Diet and Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Metabolic Syndrome
Effects of Genistein in Postmenopausal Women With Metabolic Syndrome
The 15-25% of the population of developed countries suffers for metabolic syndrome. It is associated with a 2-4 fold increase in cardiovascular morbility and mortality and with a 5- 9 fold increase in developing type II diabetes.
- Trial name
- NCT01664650
- Testing
- Genistein
- Where
- 3 sites in Italy
- Volunteers
- 120 people
- Sponsor
- University of Messina
Obesity, Pre-diabetes
Chromium Effects on Insulin and Vascular Function in People at Risk for Diabetes
The purpose of this study is to investigate the effects of Chromium on glucose tolerance and endothelial function in people at risk for type II diabetes.
- Conditions
- Obesity, Pre-diabetes, Insulin Resistance, Impaired Glucose Tolerance
- Trial name
- NCT00067626
- Testing
- Chromium
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Griffin Hospital
Prediabetes
Preventing Diabetes in Those at Risk by Having a Facilitator and Family Doctor Encourage Healthy Activity and Eating Habits
Nearly six million Canadians are living with an increased risk of diabetes (prediabetes) and approximately 50% of these will develop type 2 diabetes within five years.
- Trial name
- FLIP (NCT01589835)
- Testing
- Lifestyle changes
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of British Columbia
Pre-diabetes
The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin Secretion
Glucose-dependent insulinotropic polypeptide (GIP) is a hormone produced in the intestine. It is released immediately after meal ingestion and increases insulin release. This, in turn, helps reduce blood glucose levels.
- Trial name
- NCT01951729
- Testing
- Control, Xenin-25 without atropine, GIP without atropine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sedentary Lifestyle, Physical Activity
A Mobile Based Diabetes Prevention Program
The goals of the study are to: 1. Assess effect sizes of our mDPP intervention on weight loss, physical activity, dietary intake, and fasting plasma glucose (FPG) levels from baseline to 5 months as compared to a control group.
- Conditions
- Sedentary Lifestyle, Physical Activity, Pre-Diabetic
- Trial name
- NCT01579292
- Testing
- Mobile phone based physical activity with intervention, Pedometer Only
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes, Weight Loss
De Por Vida: A Diabetes Risk Reduction Intervention for Hispanic Women
This pragmatic randomized clinical trial will assess the efficacy, cost, and sustainability of a culturally tailored weight-loss program targeting obese Hispanic women with pre-diabetes or T2D.
- Conditions
- Diabetes, Weight Loss, PreDiabetes, Obesity
- Trial name
- NCT03113916
- Testing
- Behavioural Lifestyle Intervention
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cushing Syndrome
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome
This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the efficacy, safety and pharmacokinetics (PK) of relacorilant in patients with endogenous Cushing syndrome and concurrent type 2 diabetes…
- Trial name
- GRACE (NCT03697109)
- Testing
- Relacorilant
- Where
- 64 sites in United States, Austria and 9 more
- Volunteers
- 152 people
- Sponsor
- Corcept Therapeutics
Diabetes Mellitus, Type 2
A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
An open-label, phase II study to assess the acute and chronic effects of empagliflozin (BI 10773)on fasting and postprandial glucose homeostasis in patients with IGT and type 2 diabetes mellitus and assess the acute effects of…
- Trial name
- NCT01248364
- Testing
- BI 10773
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2, Family Health
Family-based Prevention of Diabetes Through Eating Habits and Physical Activity
Introduction: Type 2 diabetes represents a growing health risk for the society. An easy-access and low-cost intervention for the whole family will be developed to help families with (at risk of) type 2 diabetes maintain…
- Conditions
- Diabetes Mellitus, Type 2, Family Health, Health Behavior, Healthy Lifestyle
- Trial name
- GO_EASY (NCT05694351)
- Testing
- Healthy meals and physical activity in families with type 2 diabetes
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Slagelse Hospital