Clinical trials: PreDiabetes, completed
Diabetes Mellitus, Type 2, PreDiabetes
T-UP: Engaging Vulnerable Students in Diabetes Prevention
The goal of this study is to enhance reach and uptake of diabetes prevention among young adults, with a focus on recruiting underserved and high-need students who face additional challenges, including food and financial…
- Trial name
- NCT06385015
- Testing
- Tailored DPP Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Type 2 Diabetes Mellitus
The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes
The purpose of this investigation is to evaluate whether exenatide, a type 2 diabetes medication, will improve the function of the innermost part of the arterial wall called the endothelium after a fat-enriched meal and to…
- Trial name
- NCT01181986
- Testing
- Exenatide SC, Exenatide IV, Exendin-9
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Carl T. Hayden VA Medical Center
Prediabetes, Cardiovascular Disease
Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Cardiovascular disease (CVD) is largely a lifestyle-related condition that is the #1 killer of adults in the United States. Our work is aimed at understanding how short-term increases in blood sugar, like those that accompany…
- Trial name
- NCT02364570
- Testing
- Glucose (100g), Glucose (75g), Whole Eggs
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Prediabetes (Impaired Fasting Glucose and/or Impaired Glucose Tolerance)
Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes
The purpose of this study is to determine whether Rubus occidentalis extract could improve fasting or postprandial serum glucose levels, and related metabolic markers among patients with prediabetes (impaired fasting glucose…
- Trial name
- NCT01964703
- Testing
- Rubus occidentalis extract
- Volunteers
- 29 people
- Sponsor
- Korea University Anam Hospital
Prediabetes, Type 2 Diabetes
Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes
Given the data on the active ingredients of Totum-63, this research aims to evaluate the effect of its chronic consumption (24 weeks) on glucose and lipid homeostasis and especially on fasting plasma glucose in volunteers with…
- Conditions
- Prediabetes, Type 2 Diabetes, Hypertriglyceridemia, Obesity
- Trial name
- TOTUM-63 TWO (NCT02868177)
- Testing
- Totum-63
- Where
- 6 sites in France, Ireland and 2 more
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Pre-Diabetes
15-minute Individual Consultation to Improve Blood Glucose Control in Pre-diabetes
This research will assess the feasibility of conducting a randomised control trial to evaluate the effectiveness of a 15-minute one-to-one consultation to improve blood glucose control in pre-diabetes.
- Trial name
- NCT03483129
- Testing
- Consultation
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Prediabetic State, Insulin Resistance
Effect of Linagliptin + Metformin vs Metformin Alone in Patients With Prediabetes
Type 2 diabetes is a worldwide epidemic disease, and preventive strategies are needed to face this health problem. The goal of this clinical trial is to evaluate the effect of linagliptin + metformin vs metformin alone on…
- Trial name
- PRELLIM (NCT03004612)
- Testing
- Linagliptin + metformin, Metformin
- Where
- Mexico
- Volunteers
- 144 people
- Sponsor
- Universidad de Guanajuato
Coronary Artery Disease, Dysglycemia
Coronary Artery Disease Severity in Newly Diagnosed Dysglycemia
This cohort study will measure how severe is the coronary artery disease (CAD), at time of CAD diagnosis, clinically and angiographically in the different cohorts of newly diagnosed diabetes and prediabetes versus normal glycemia…
- Trial name
- NCT05210972
- Testing
- Cardiac catheterization
- Where
- Saudi Arabia
- Volunteers
- 150 people
- Sponsor
- Saud Al Babtain Cardiac Center
Prediabetes
Glycemic Response to Two Doses of Low Sugar Apple Juice
Single center, double-blind, randomized controlled cross-over trial with four treatments and four time points. The study has three primary objectives.
- Trial name
- HB-RCT2-2015 (NCT04747639)
- Testing
- 500 ml glucose-depleted apple juice, 500 ml conventional apple juice, 250 ml glucose-depleted apple juice
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Clinical Research Center Kiel GmbH
Impaired Glucose Tolerance, Type 2 Diabetes Mellitus
Anti-Inflammatory Effects of Pioglitazone
There is increasing evidence that inflammation plays a role in progression and destabilization of atherosclerotic plaque. FDG-PET can visualize activated metabolic activity of inflammatory cells.
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes Mellitus, Atherosclerosis
- Trial name
- NCT00722631
- Testing
- Pioglitazone, Glimepiride
- Where
- Japan
- Volunteers
- 70 people
- Sponsor
- Kurume University
Impaired Glucose Tolerance, Type 2 Diabetes
Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
The purpose of this study is to determine if increased intake of low-fat milk products and calcium as part of a calorie restricted diet helps achieve a healthier body weight and body composition and decrease blood glucose levels…
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00564551
- Testing
- High dairy and calcium intake, Usual intake
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Calgary
PreDiabetes, Circadian Dysregulation
Morning Light Treatment to Improve Glucose Metabolism
The primary purpose of this pilot study is to test a novel head worn light device (Re-Timer®) as an intervention to improve glucose metabolism in people with prediabetes.
- Trial name
- ML (NCT03188263)
- Testing
- Bright Light, Dim Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Traumatic Brain Injury
Early Digital, Analyte and Neurologic Biomarkers of Acute and Chronic Brain Injury and Recovery in CQT Instructors
Repetitive blast exposure has been shown to lead to more severe neurobehavioral impairments versus a single exposure. Blast-induced Traumatic Brain Injury (TBI) can lead to short- and long-term adverse outcomes Even mild brain…
- Trial name
- NCT05917665
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Overweight and Obesity
The Effect of Extended Use of the EPITOMEE CAPSULE (ELECT)
The Effect of Extended Use of the Epitomee Capsule on BodyWeight in subjects with Overweight and Obesity with and without Prediabetes
- Trial name
- NCT04994769
- Testing
- Epitomee Capsule
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Epitomee medical
Cystic Fibrosis, Glucose Metabolism Disorders
One Year Glargine Treatment in CFRD Children and Adolescents
Glargine treatment can improve the clinical features in Cystic Fibrosis patients affected by glucose derangements
- Trial name
- NCT00483769
- Testing
- Glargine
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Obesity, Heart Failure
The Metabolic Effects of Empagliflozin in Patients With High Risk of Heart Failure
The aim of this trial is to assess the effect of Empagliflozin on lipid and glucose metabolism as well as volume homeostasis and renal function in elderly and obese patients with increased risk of developing heart failure.
- Trial name
- NCT05042973
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Denmark
- Volunteers
- 165 people
- Sponsor
- Jacob Moller
Obesity, Glucose Intolerance
Vitamin D to Improve Glucose Metabolism and Reduce Inflammation in Obese Adolescents
The investigators' project will study the effects of optimizing the vit D status of obese adolescents on markers of glucose metabolism and inflammation.
- Conditions
- Obesity, Glucose Intolerance, Inflammation
- Trial name
- NCT00994396
- Testing
- Vitamin D 3 cholecalciferol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Missouri-Columbia
Type2 Diabetes Mellitus, Hypertension
The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)
This study will compare the low-sodium/low-fat DASH (Dietary Approaches to Stop Hypertension) diet with a very low-carbohydrate diet, helping us to better understand how two different dietary approaches may help participants…
- Conditions
- Type2 Diabetes Mellitus, Hypertension, PreDiabetes, Overweight and Obesity
- Trial name
- NCT03729479
- Testing
- DASH diet, Very low carbohydrate, ketogenic diet, Extras
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Michigan
Diabetes Mellitus
Prevent/Delay Development of Type 2 Diabetes in Subjects With Impaired Glucose Homeostasis Treated With Acarbose in Primary Care
The purpose of the study is to determine if the administration of small doses of Acarbose can prevent or delay the appearance of Type 2 Diabetes Mellitus in a population of subjects with prediabetes.
- Trial name
- NCT01010100
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- 23 sites in Spain
- Volunteers
- 204 people
- Sponsor
- Bayer