Clinical trials: PreDiabetes, completed
Blood Glucose, Blood Insulin
Impact of Fluid Milk on Post-meal Glycemia and Insulinemia in Overwt/Obese Adults
Blood sugar and insulin levels after a meal may be altered by the food and beverages a person consumes. Keeping a healthy blood sugar level may help prevent and manage type 2 diabetes and related diseases.
- Trial name
- S37 (NCT01951287)
- Testing
- Acute beverage (water) consumption, Acute beverage (Black Coffee) consumption, Acute beverage (Orange Juice) consumption
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Purdue University
Metabolism Disorder, Lipid, Metabolism Disorder, Glucose
Compare the Impact of Xuezhikang and Atorvastatin on Glucose Metabolism in Dyslipidemia Patients With Prediabetes
This study is a prospective, randomized, open-label, multi-center trial. The primary objective of the study is to assess whether XZK 1200mg/d, compared to atorvastatin 20mg/d, has a favorable impact on HbA1c levels at 24 weeks of…
- Trial name
- XTREME (NCT05238012)
- Testing
- Xuezhikang Capsule, Atorvastatin Calcium Tablets
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Heart Health Research Center
PreDiabetes
Effect of Green Tea on Obese Pediatrics With Prediabetes
The aim of this research is to evaluate the safety and efficacy of green tea in obese pediatrics with prediabetes versus the metformin therapy alone that is given to these patients.
- Trial name
- NCT06229795
- Testing
- Green Tea Leaf Extract Decaffeinated, Metformin Hydrochloride 500 MG
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Insulin Resistance, Abdominal Obesity
Pilot Study With GFT505 (80mg) in Patients With Insulin Resistance and Abdominal Obesity
The purpose of this study is to demonstrate the efficacy on insulin sensitivity of GFT505 at 80mg/d in male patients with insulin resistance and abdominal obesity. Evaluation will be made using a glucose clamp technique.
- Trial name
- NCT01271777
- Testing
- GFT505 80mg
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Genfit
Prediabetic State
Investigation of Milk Peptides (Pep2Dia®) on Postprandial Blood Glucose Profile in Prediabetic Subjects
The goal is to investigate the 180 min postprandial response on blood glucose and insulin levels after intake of Pep2Dia® in two different dosages compared to placebo in the context of a meal challenge test, providing 75 g of…
- Trial name
- NCT04375449
- Testing
- Pep2dia, maltodextrin
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.
Prediabetes, Insulin Resistance
Comparison of Time-Restricted Feeding Versus Grazing
The purpose of this pilot study is to find out what eating meals in a short time period early in the day (time-restricted feeding) versus eating meals spread out during the day (grazing) does to the body's ability to control…
- Conditions
- Prediabetes, Insulin Resistance, Vascular Diseases
- Trial name
- TIMED EATING (NCT01895179)
- Testing
- Time-Restricted Feeding, Grazing
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Prediabetic State, Overweight and Obesity
Diabetes Prevention for Mexican Americans
This study tests a culturally tailored lifestyle intervention designed to prevent, or delay onset of, T2DM in Mexican Americans with prediabetes.
- Trial name
- NCT03208010
- Testing
- Diabetes Prevention Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas at Austin
Pre Diabetes, Obesity
Study of the Food Order Behavioral Intervention in Prediabetes
Investigators have previously shown that eating carbohydrates after protein or vegetables resulted in reduced glucose and insulin excursions over 180 min in patients with T2DM and in individuals with prediabetes as well.
- Trial name
- NCT03896360
- Testing
- Food order behavioral intervention plus standard care, Standard Care
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Weill Medical College of Cornell University
Type 2 Diabetes
The Effect of Vinegar on Glucose and Lipid Metabolism in Subjects With Impaired Glucose Tolerance or Type 2 Diabetes
This open, randomized, cross-over, placebo-controlled study aims to investigate the effects of vinegar on glucose metabolism, endothelial function and circulating lipid levels in subjects with impaired glucose tolerance or type 2…
- Trial name
- NCT02309424
- Testing
- Vinegar
- Volunteers
- 20 people
- Sponsor
- Attikon Hospital
Metabolic Syndrome, PreDiabetes
Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes
The objective of this trial is to compare the effects of a healthy, lean beef diet and an average American, United States Department of Agriculture (USDA) style diet, that is low in saturated fatty acids (SFA), on insulin…
- Trial name
- NCT03202680
- Testing
- USDA Style Diet, Lean Beef Diet
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Back Pain Lower Back Chronic, Back Pain
Assessing the Effects of HbA1c Reduction on Alleviating Nonspecific Back Pain
Prediabetes, characterized by elevated HbA1c levels, is a common precursor to type 2 diabetes mellitus. Recent studies have suggested a potential link between prediabetes and nonspecific back pain.
- Conditions
- Back Pain Lower Back Chronic, Back Pain, Pre Diabetes, Diabetes
- Trial name
- NCT06064058
- Testing
- Ghazwan program, Standard management
- Where
- Iraq
- Volunteers
- 90 people
- Sponsor
- University of Baghdad
Pre Diabetes, Overweight
A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals
A randomised, double blind, placebo controlled parallel study to examine the effects of a dose range of PeptiControl, a plant-based ingredient, in pre-diabetic males and females.
- Trial name
- NCT06440213
- Testing
- PeptiControl™ (Low - Dose 435 mg/day), PeptiControl™ (Mid - Dose 870 mg/day), PeptiControl™ (High - Dose 2610 mg/day)
- Where
- 4 sites in India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Diabetes
Metabolic Effects of GH and IGF-I in Growth Hormone Deficient(GHD) and Diabetes and Impaired Glucose Tolerance(IGT)
The aim of this study is to measure effects of the combined treatment with GH and IGF-I on glucose sensitivity and body composition in patients with GHD and IGT or diabetes.
- Trial name
- NCT01020955
- Testing
- NutropinAq (GH) and Increlex (IGF-I)
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Karolinska University Hospital
Impaired Glucose Tolerance
Mechanisms of Exercise Resistance in Metabolic Disease
This project will determine exercise capacity and molecular markers of the response to acute exercise in human subjects with impaired or normal glucose tolerance.
- Trial name
- NCT03945435
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Insulin Sensitivity, Glucose Intolerance
The Effects of Sea Buckthorn and Strawberry on Postprandial Glycaemia, Insulinemia and Appetite
The effects of strawberry and sea buckthorn on postprandial glycaemia and insulinemia as well as on metabolic profiles were examined in overweight or obese male subjects.
- Trial name
- OPUS-WP3C (NCT02412995)
- Testing
- Meal sequence 1-2-3, Meal sequence 1-3-2, Meal sequence 2-3-1
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sleep Apnea, PreDiabetes
Technology-Supported Treatment of Sleep Apnea in Prediabetes
Despite the efficacy of intensive lifestyle interventions in prediabetes, the incidence of diabetes is rising, and thus there is a critical need for additional strategies to prevent diabetes and to reduce its cardiovascular…
- Conditions
- Sleep Apnea, PreDiabetes, Overweight or Obesity
- Trial name
- TECH (NCT04225507)
- Testing
- Diet and exercise coaching, CPAP Treatment
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Chicago
Impaired Glucose Tolerance
HSK7653 in Chinese Patients with Impaired Glucose Tolerance
This study is being done to evaluate the efficacy, safety of HSK7653 in chinese participants with impaired glucose tolerance.
- Trial name
- NCT04727580
- Testing
- HSK7653 10mg Q2W, HSK7653 25mg Q2W
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Type 2 Diabetes, Obesity, Prediabetes
The Influence of Glucose Flux on Fat Synthesis in a Whole Body Calorimeter
The study is carried out to find out the inclusion of high and low glycaemic index foods to daily meals and how they impact 24 hour blood glucose fluctuations and energy regulation.
- Trial name
- NCT02631083
- Testing
- Breakfast, lunch, snack and dinner
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation