Clinical trials: PreDiabetes, completed
Metabolic Syndrome
Metabolic Syndrome Risk Factor in IGT: STOP-NIDDM Trial
The aim of the study was to analyse the independent and joint effects of the components of the metabolic syndrome (MetS) on the incidence of diabetes in people with impaired glucose tolerance (IGT) and to assess the effect of…
- Trial name
- NCT00629213
- Testing
- acarbose
- Where
- Germany
- Volunteers
- 1,429 people
- Sponsor
- GWT-TUD GmbH
Prediabetes, Cystic Fibrosis (CF)
CGM Dynamic Index for Predicting Prediabetes in Cystic Fibrosis
The primary objective of this pilot study is to develop a CGM-based model to predict the progression from prediabetes to diabetes in individuals with cystic fibrosis.
- Conditions
- Prediabetes, Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes
- Trial name
- NCT06642610
- Testing
- CGM Dynamic Index (CDI)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Prediabetes
Prevention of Type 2 Diabetes Mellitus by Changes in Diet
investigators evaluated the efficacy of two types of diet with different macronutrients, on prevention or delaying the onset of type 2 diabetes in subjects with either impaired fasting glucose (IFG) or impaired glucose tolerance…
- Trial name
- NCT02250066
- Testing
- Diet
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Ilam University of Medical Sciences
Type II Diabetes Mellitus
Effects of a Spiced Meat Patty on Inflammation in Men With Type 2 Diabetes
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01076829
- Testing
- Spice polyphenols
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Apical Periodontitis, Insulin Resistance
Serum Pro-Diabetes Inflammation Biomarkers in Patients With Apical Periodontitis.
Inflammation is a common factor of chronic periodontitis and diabetes. However, to date, there is no scientific evidence supporting a causal effect of the inflammation created by apical periodontitis on the onset of insulin…
- Conditions
- Apical Periodontitis, Insulin Resistance, PreDiabetes, Diabetes; Stable
- Trial name
- NCT04824209
- Where
- 2 sites in Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Type 2 Diabetes, Impaired Glucose Tolerance
Efficiency and Cost-effectiveness of a Culturally Adopted Lifestyle Intervention Program - the MEDIM Study.
An increasing proportion of Sweden's population comprises non-European immigrants, who constitute a high risk-population for T2D.
- Conditions
- Type 2 Diabetes, Impaired Glucose Tolerance, Obesity, Physical Activity
- Trial name
- MEDIM (NCT01420198)
- Testing
- Lifestyle intervention
- Where
- Sweden
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Region Skane
Pre-diabetes
Impact of High Fiber and Vegetal Protein Diet on Gut Health and Immunity Biomarkers in Prediabetic Patients
The research area that focuses on the links between nutrition and health, nutrition and the immune system as well as nutrition-related public health interventions, which often falls into the gap between the agricultural and…
- Trial name
- PreVegDiet (NCT06147323)
- Testing
- Normal Healthy Diet, Seaweed Group
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Impaired Glucose Tolerance (IGT)
Postmarketing Clinical Study on AO-128
The purpose of open-label study is to evaluate the efficacy and safety of AO-128 (Voglibose) 0.6 mg/day in patients with impaired glucose tolerance (IGT) who had been non-responsive to diet therapy and exercise therapy, and…
- Trial name
- NCT02287402
- Testing
- AO-128
- Volunteers
- 197 people
- Sponsor
- Takeda
Impaired Glucose Tolerance
Physical Exercise Versus Rosiglitazone in CAD and Prediabetes
The aim of this study is to prospectively assess the relative benefits of either treatment with rosiglitazone or physical exercise on endothelial function in patients with impaired fasting glucose or impaired glucose tolerance…
- Trial name
- NCT00675740
- Testing
- rosiglitazone, physical exercise, control
- Volunteers
- 45 people
- Sponsor
- University of Leipzig
Polycystic Ovary Syndrome, Anovulation
Inositol Supplementation to Treat PCOS (INSUPP-PCOS)
To determine if Inositol, a dietary supplement, will improve ovarian and adrenal androgen excess in women with Polycystic Ovarian Syndrome(PCOS).
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Hyperandrogenism, Insulin Resistance
- Trial name
- INSUPP-PCOS (NCT03864068)
- Testing
- Inositol
- Where
- 2 sites in United States
- Volunteers
- 154 people
- Sponsor
- Milton S. Hershey Medical Center
PreDiabetes
Effect of BFR Training on Glycemic Control, Functional Activity and Quality of Life in Individuals With Pre-diabetes
The aim of this study is to determine the effects of blood flow restriction training on glycemic control and functional activity in participants with prediabetes.
- Trial name
- NCT05411640
- Testing
- Aerobic exercise with Blood flow restriction, Aerobic exercise without Blood flow restriction, Patient Education and dietary modification
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Feeding Patterns, Sleep
Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition
The purpose of this study is to determine whether advancing the timing of home parenteral nutrition from overnight to daytime regimens leads to improved glucose profiles and sleep quality, and other changes in plasma metabolic…
- Conditions
- Feeding Patterns, Sleep, Glucose Intolerance, Short Bowel Syndrome
- Trial name
- NCT04743960
- Testing
- Time-of-day of parenteral nutrition provision
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Impaired Glucose Tolerance
Vitamin D for the Prevention of Diabetes Type 2
The prevalence of type 2 diabetes is increasing, which for most societies has considerable consequences not only regarding health but also economy.
- Trial name
- NCT00685594
- Testing
- cholecalciferol
- Where
- Norway
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of Tromso
PreDiabetes
Weight Loss for Prediabetes Using Episodic Future Thinking
The goals of the UH3 are to assess the effectiveness of adding Episodic Future Thinking (EFT) to the investigators standard behavioral weight control program to improve weight loss, delay discounting (DD), working memory…
- Trial name
- MINDD4 (NCT03670602)
- Testing
- Episodic Future Thinking, Daily Check in
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- State University of New York at Buffalo
Type 2 Diabetes Mellitus
A Diabetes Prevention Study Targeting High Risk Individuals With Education and Ongoing Support
The study aims to identify people at high diabetes risk within the local population and then implement and evaluate a pragmatic and low-cost diabetes prevention programme containing structured education on lifestyle, physical…
- Trial name
- PREVENTION (NCT00677937)
- Testing
- Modified DESMOND education and ongoing support
- Where
- United Kingdom
- Volunteers
- 748 people
- Sponsor
- University Hospitals, Leicester
Impaired Glucose Tolerance, Abdominal Obesity
Pilot Study With GFT505 (80mg) in Patients Presenting With Impaired Glucose Tolerance and Abdominal Obesity.
The purpose of this study is to evaluate the efficacy of GFT505 80mg compared with placebo in improving Oral Glucose Tolerance Test (OGTT), in patients with impaired glucose tolerance and abdominal obesity, and to assess the…
- Trial name
- NCT01275469
- Testing
- GFT505 80mg
- Where
- 20 sites in France
- Volunteers
- 47 people
- Sponsor
- Genfit
Insulin Resistance, Prediabetic State
Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.
This study is being done to understand metformin's mechanisms of action regarding glucose production, protein metabolism, and mitochondrial function.
- Trial name
- NCT01956929
- Testing
- Metformin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pre-diabetes, Undiagnosed Diseases
A Pivotal Clinical Investigation Confirming the Safety and Accuracy of the Glyconics-DS in Assessment of Glycated Nail Keratin in Individuals With Unknown Diabetes Status and Performance Evaluation of the Glyconics SW Package
The main clinical study objective is to confirm the accuracy of the Glyconics-DS spectrometer when used in its intended medical purpose population, i.e., in individuals with unknown diabetes risk.
- Trial name
- ANODE03 (NCT06261944)
- Testing
- Near-infrared (NIR)
- Where
- Spain
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Glyconics Ltd
Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline
Glucose Variability and Cognition in Prediabetes
This study examines the association of variability in glucose values over a 10-day period with cognitive function and AD risk markers among individuals with prediabetes, aged 50 or older.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, PreDiabetes, Aging
- Trial name
- NCT04201600
- Testing
- Continuous Glucose Monitoring System (CGMS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore