Clinical trials: PreDiabetes, completed
PreDiabetes
Prediabetes and Non Obstructive Coronary Atherosclerosis.
Objectives: Prediabetes may condition an early endothelium dysfunction, and the development of non obstructive coronary stenosis (NOCS).
- Trial name
- NCT03553030
- Testing
- coronary artery angiography
- Where
- Italy
- Volunteers
- 172 people
- Sponsor
- University of Campania Luigi Vanvitelli
Pre-diabetes
Common Genetic Variation and Type 2 Diabetes
Type 2 diabetes is a common metabolic disorder arising from a complex interaction between genetic predisposition and the environment.
- Trial name
- NCT00707616
- Testing
- Oral glucose tolerance test
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight and Obesity, PreDiabetes
Effects of Gelesis200 on Appetite Parameters, Food Intake, and Glycemic Control in Overweight or Obese Prediabetic Subjects: A Sub-Study of LIGHT-UP
This study evaluates the effects of Gelesis200 on Appetite Parameters, Food Intake, and Glycemic Control in Overweight or Obese Prediabetic Subjects: A Sub-Study of LIGHT-UP.
- Conditions
- Overweight and Obesity, PreDiabetes, Type2 Diabetes
- Trial name
- MATCH (NCT03622424)
- Testing
- Gelesis200
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Gelesis, Inc.
Glucose Metabolism Disorder
Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption
Experiments have shown that some artificial sweeteners like those in diet soda can cause changes in how the body responds to and uses sugar.
- Trial name
- NCT02520258
- Testing
- Oral glucose tolerance test (OGTT), Diet soda containing aspartame only
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
PreDiabetes, Obesity
Telehealth Diabetes Prevention Intervention for African American Youth
The Telehealth Diabetes Prevention Intervention for the Next Generation of African American Youth (TELE-GEN) pilot study will evaluate the implementation and early efficacy of a telehealth diabetes prevention intervention for…
- Conditions
- PreDiabetes, Obesity, Obesity, Childhood
- Trial name
- TELE-GEN (NCT04618458)
- Testing
- Power to Prevent
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Mississippi Medical Center
Prediabetic State
A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program
This proposed project will translate evidence-based strategies for diabetes prevention within the framework of an existing and highly utilized pharmacist-led diabetes care program.
- Trial name
- NCT02384109
- Testing
- Shared decision-making with pharmacists, Standard care from primary care providers
- Where
- 20 sites in United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Type 2 Diabetes Mellitus, PreDiabetes
Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus
This study is conducted to examine GLP-1, insulin resistance and insulin sensitivity portfolio in Malay, Chinese and Indian populations in Malaysia and to study the effect of DPPIV inhibitor in T2DM patients with different…
- Trial name
- GLP-1 (NCT03659461)
- Testing
- Sitagliptin
- Where
- Malaysia
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Overweight, Obesity
Effects of Obex in Overweight and Obese Patients
Obesity is an important and growing public health worldwide Obesity is highly related to the development of metabolic syndrome, diabetes, cardiovascular diseases and cancer An extensive body of evidence from efficacy trials has…
- Trial name
- NCT02145442
- Testing
- Obex
- Where
- Cuba
- Volunteers
- 40 people
- Sponsor
- Catalysis SL
PreDiabetes, Hyperglycemia
Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs
The purpose of this research study is to compare the effectiveness of a fully automated digital diabetes prevention program to standard of care human coach-based diabetes prevention programs for promoting clinically meaningful…
- Conditions
- PreDiabetes, Hyperglycemia, Glucose, High Blood, Overweight
- Trial name
- NCT05056376
- Testing
- Digital Diabetes Prevention Program (dDPP), Human Coach-based Diabetes Prevention Program (hDPP)
- Where
- 2 sites in United States
- Volunteers
- 368 people
- Sponsor
- Johns Hopkins University
Perimenopausal Disorder, Impaired Glucose Tolerance
Effect of a Food Supplement Based on Nigella Sativa Seeds Oil and Vitamin E on Glyco-lipid Parameters in Dysglycemic and Dyslipidemic Perimenopausal Women
A total of 120 subjects in one center will be enrolled and will be divided into two treatment groups of 60 subjects each with 1:1 allocation ratio. Permuted block randomization will be used.
- Conditions
- Perimenopausal Disorder, Impaired Glucose Tolerance, Impaired Fasting Glycemia
- Trial name
- NCT06901076
- Testing
- Nisatol
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Pre Diabetes, Diabetes
Comparing Diabetes Prevention Programs
The purpose of this study is to compare the effectiveness and costs of two programs,the Diabetes Prevention Program and the community-developed Healthy Living Program, delivered in an primary care practice.
- Trial name
- NCT01409889
- Testing
- Diabetes Prevention Program, Healthy Living Program
- Where
- 4 sites in United States
- Volunteers
- 92 people
- Sponsor
- University of Rochester
Diabetes Mellitus, Glucose Intolerance
Japan Prevention Trial of Diabetes by Pitavastatin in Patients With Impaired Glucose Tolerance (J-PREDICT)
The purpose of this study is to evaluate the effects of pitavastatin for preventing diabetes in a population with impaired glucose tolerance.
- Trial name
- NCT00301392
- Testing
- life-style intervention, Life style interventions plus concomitant use of pitavastatin.
- Where
- Japan
- Volunteers
- 1,240 people
- Sponsor
- Tokyo University
PreDiabetes, Cardiovascular Diseases
Individualized Nutrition Therapy for Preventing or Delaying Onset of Type-2 Diabetes
The overall aim of this feasibility study is to conduct a randomized, controlled intervention providing adults with prediabetes either an individualized nutrition therapy (INT) intervention that contains individualized dietary…
- Trial name
- NCT05161897
- Testing
- Individualized Nutrition Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- George Mason University
Chronic Kidney Diseases, Hypertension
Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease
Real clinical practice register of Albuminuria detection in patients with previously undiagnosed chronic kidney disease
- Conditions
- Chronic Kidney Diseases, Hypertension, Chronic Heart Failure, Ischemic Heart Disease
- Trial name
- AURA (NCT05690009)
- Where
- Russia
- Volunteers
- 4,580 people
- Sponsor
- Eurasian Association of Therapists
PreDiabetes, Metabolic Syndrome
Women's Lifestyle Balance Study
This pilot study aims to determine whether adding a sleep extension and sleep hygiene intervention to an existing lifestyle improvement program improves its efficacy for weight loss in those at risk for diabetes and…
- Conditions
- PreDiabetes, Metabolic Syndrome, Overweight
- Trial name
- LB (NCT03184337)
- Testing
- CDC's PreventT2 Program, CDC's PreventT2 Program with Added Sleep Content
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, San Francisco
Pre-diabetes
Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)
This will be a double-blind, randomized, placebo-controlled, single dose study of (+)- epicatechin with one 30mg dose/day for a total of 7 days
- Trial name
- Epicatechin (NCT02656212)
- Testing
- epicatechin
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Veterans Medical Research Foundation
Impaired Glucose Tolerance
The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes
The purpose of this study is to compare the effects of exenatide versus metformin on vascular health with chronic (3-month) therapy and during a 2-hour period following a meal in patients with pre-diabetes.
- Trial name
- NCT00546728
- Testing
- Exenatide, Metformin
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- St. Paul Heart Clinic
PreDiabetes, Postprandial Hyperglycemia
Mealtime Walking Study to Improve Postprandial Metabolic Response
This randomized crossover trial will investigate the metabolic responses following the consumption of a bagel+juice meal under 3 conditions: control, fiber (positive control), and postmeal walk in15 healthy adults.
- Trial name
- NCT04499287
- Testing
- 15-minute walk at preferred walking speed., Fiber, control
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pre-diabetes
Vitamin D in Minorities With Prediabetes
Vitamin D supplementation in minority subjects with both pre-diabetes and low vitamin D levels will delay the development of diabetes.
- Trial name
- NCT00876928
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Charles Drew University of Medicine and Science
Overweight and Obesity, Prediabetes
TREAT to Improve Cardiometabolic Health
Over half of American adults have overweight or obesity and are at high risk of developing type 2 diabetes and cardiovascular diseases.
- Trial name
- NY-TREAT (NCT04465721)
- Testing
- TRE, HABIT
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Columbia University