Clinical trials: PreDiabetes, completed
Increased Insulin
The Effect of Andrographis Paniculata to GLP-1, Fasting Insulin, Insulin 2-h Post OGTT, and HOMA-IR
Prevalence of type 2 diabetes have been increased, but medications had not been well, so that needed new alternatives. A new approach used in management of type 2 diabetes is incretin based therapy.
- Trial name
- NCT03455049
- Testing
- Andrographis Paniculata Ext
- Where
- Indonesia
- Volunteers
- 73 people
- Sponsor
- Universitas Indonesia
Prediabetic State, Diabetes Mellitus
A Mobile Phone-based Program for Adults With Prediabetes
Type 2 diabetes mellitus (T2DM) can be prevented through weight loss and increased physical activity, yet its prevalence continues to rise.
- Trial name
- NCT03025607
- Testing
- JOOL Health Mobile Phone Application
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Michigan
Prediabetes
Effects of Standing on Glycemia in Prediabetic Adults
The study is a crossover, pilot trial examining the acute effects of standing on blood sugar in prediabetic, working adults. Participants will complete oral glucose tolerance testing, once while sitting and once while standing.
- Trial name
- NCT01884792
- Testing
- Sitting OGTT, Standing OGTT, Sitting CGM
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Insulin Resistance
Evaluation of the Impact of a Nutritional Supplement Made of Vegetable Oils in People at Risk of Diabetes
Metabolic and cardiovascular diseases are the first cause of morbidity and mortality throughout the world, including Latin America and Colombia.
- Trial name
- NCT03512665
- Testing
- Full dose supplement, Low dose Supplement, Control Oil
- Where
- Colombia
- Volunteers
- 25 people
- Sponsor
- University of Los Andes, Columbia
Body Weight, Impaired Glucose Tolerance in Obese
Effect of Cabergoline on Weight and Glucose Tolerance
The aim of this study is to determine the efficacy of cabergoline, a long-acting dopamine receptor agonist, on body weight and blood glucose in healthy obese adults. This is a randomized double-blind placebo controlled study.
- Trial name
- NCT01395602
- Testing
- Cabergoline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
Prediabetes, Gestational Diabetes
Treating Prediabetes in the First Trimester
The investigators plan to study a sample of women with prediabetes (diagnosed by Hemoglobin A1c (HbA1c) 5.7-6.4% or fasting plasma glucose (FPG) 92-125 mg/dL) in the first trimester of pregnancy, and patients will be randomized…
- Trial name
- NCT01926457
- Testing
- Treatment of Prediabetes
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity
Physical Activity Following Surgery Induced Weight Loss
The primary objective of this study will be to determine the effects of physical activity in patients during substantial surgery-induced weight loss.
- Trial name
- NCT00692367
- Testing
- Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type 2 Diabetes Mellitus, Prediabetes
Effect of Iron Reduction by Phlebotomy for Type 2 Diabetes
High tissue iron is a risk factor for diabetes even within the broad normal range of normal human values. In order to demonstrate the benefits of reducing iron on glucose homeostasis and to better define the parameters for larger…
- Trial name
- NCT02468037
- Testing
- Phlebotomy
- Volunteers
- 12 people
- Sponsor
- University of Utah
Diabetes Mellitus, Type 2, Prediabetic State
Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
The goal of this study is to explore the effects of FeatForward on physical activity and cardio-metabolic risk factors. The study will be implemented as a 2-arm randomized controlled trial (RCT) comparing the effects of…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Hypertension, Prehypertension
- Trial name
- NCT02551640
- Testing
- FeatForward App (on study smartphone)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment, Prediabetes
Piedmont Aging, Cognition & Exercise Study-2
The purpose of this research study is to examine the effects of high and low intensity exercise for those with mild memory loss and pre-diabetes.
- Trial name
- PACE-2 (NCT02312843)
- Testing
- Exercise/Aerobic, Exercise/Stretching
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Diabetes Mellitus, Type 2, Obesity
The Glycemic Effect of Added Sugar on Bake Beans
To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, PreDiabetes
- Trial name
- GIF (NCT03868683)
- Testing
- Glucose Reference 1, Glucose Reference 2, Glucose reference 3
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Diabetes, Prediabetes
The Usefulness of Postprandial Triglyceride for Assessment of Cardiovascular Risk
The hypertriglyceridemia at fasting status has been known to be an important risk factor for cardiovascular disease (CVD). Recently, postprandial triglyceride (TG) levels draw an attention as a superior predictor of CVD because…
- Trial name
- NCT01972542
- Testing
- Oral fat tolerance test
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Diabetes Mellitus, Type 2, PreDiabetes
Sardine-enriched Diet for Prevention Type 2 Diabetes
The hypothesis formulated is that 200 g of sardine on a weekly basis will have a favourable impact avoiding the natural development of the pathology due to changes in the biochemical profile, the anthropometrics, inflammatory…
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Diet Habit, Diabetes
- Trial name
- NCT03557541
- Testing
- Sardine, Control
- Where
- Spain
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Pre Diabetes, Type 2 Diabetes Mellitus
Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes
Prediabetes is a common condition in overweight individuals affecting approximately 35% of American adults and 30% of Australian adults.
- Trial name
- PREDICT (NCT03558867)
- Testing
- Metformin + Healthy diet, Metformin + Personalized diet
- Where
- Australia
- Volunteers
- 138 people
- Sponsor
- Garvan Institute of Medical Research
PreDiabetes, Obesity
Tolerability, Acceptance, and Utility of Intermittent CGM Use in Youth With Prediabetes
We are evaluating whether intermittent use of continuous glucose monitors (CGMs) in addition to standard nutritional counseling and physical activity counseling is associated with improved metabolic health for youth with…
- Conditions
- PreDiabetes, Obesity, Insulin Resistance
- Trial name
- NCT05505565
- Testing
- Abbott Freestyle Libre 2, Standard physical activity and nutritional counseling for prediabetes management
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Alabama at Birmingham
Pre-diabetes
Can the Health Benefits of a Walking-based Exercise Programme be Enhanced by Co-ingestion of a Lipid-lowering Drug?
Study investigates the hypothesis that an exercise programme of steady walking will have larger effects on insulin sensitivity and glycemic control when combined with Acipimox intake prior to each exercise session in people with…
- Trial name
- NCT03809793
- Testing
- Exercise Program, DXA, MRI
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Liverpool John Moores University
Prediabetes, Obesity
Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein
Diabetes is a major health concern in obese older Veterans, especially in those who are African American. The negative impact of diabetes on muscle and physical function contributes to metabolic as well as physical decline and is…
- Trial name
- VALOR-UP (NCT03835416)
- Testing
- Foods rich in high quality protein
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Diabetic Cardiomyopathy
Impact of Prediabetes on Acute Coronary Syndrome
Diabetes mellitus is one of the chronic non-communicable diseases which have emerged as a leading global health problem. According to the International Diabetes Federation Atlas guideline report, currently, there are 352 million…
- Trial name
- NCT05102851
- Testing
- Troponin, Lipid profile, HBA1C, Fasting blood glucose level, Creatinine, Body Mass Index
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pre Diabetes, Obesity
MapTrek to Increase Activity Among Patients at Risk for Type 2 Diabetes
The overarching objective of our work is to provide an inexpensive and scalable m-health tool to increase both volume and intensity of physical activity and reduce sedentary behavior in patients at risk for type 2 diabetes.
- Trial name
- NCT03193229
- Testing
- MapTrek, Fitbit
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Philip Polgreen
Overweight and Obesity, PreDiabetes
Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study
The overall goal is to determine the real-world feasibility and utility of body fat imaging using rapid MRI to enhance risk perception, induce behavioral change, and improve clinical outcomes in overweight and obese individuals.
- Conditions
- Overweight and Obesity, PreDiabetes, Type 2 Diabetes, Cardiovascular Risk Factor
- Trial name
- BODY-REAL (NCT04763772)
- Testing
- Body Fat Distribution Imaging Report, Basic Weight Information, Patient Provided
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University Hospitals Cleveland Medical Center