Clinical trials: Prebiotic
Obesity
Prebiotic Fiber as a Modifier of Satiety Hormones and Body Weight in Overweight and Obese Adults
The purpose of this study is to determine if oligofructose supplementation promotes weight loss in overweight and obese adults.
- Trial name
- NCT00522353
- Testing
- Oligofructose
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bifidobacteria, Healthy Volunteers
Effects of Xylooligosarcharide on Composition of the Human Colonic Microflora
Human and animal studies demonstrate that xylooligosaccharides (XOS) are a highly efficacious prebiotic ingredient that delivers benefits at a minimum level of 1.4 g/day (d), which is much lower than levels required by…
- Trial name
- XOS (NCT01861964)
- Testing
- Xylooligosarcharide 1.4g, Xylooligosarcharide 2.8g
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Polycystic Ovarian Syndrome (PCOS)
Effect of Theronomic Ova-All Care on Biomarkers of Ovarian Health in Adult Female With Polycystic Ovarian Syndrome
Theronomic Ova-All Care is a tribiotic health product aimed at improving ovarian health in people with polycystic ovarian syndrome (PCOS).
- Trial name
- Ova-All Care (NCT06963840)
- Testing
- Theronomic Ova-All Care
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Wellizen Australia
Constipation
Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits
The aim of the study is to confirm the effectiveness of chicory-derived prebiotic inulin-type fructans on bowel function in young children.
- Trial name
- CONSTICHILD (NCT03941925)
- Testing
- Prebiotic fructans, Non-prebiotic maltodextrin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Gut Microbiota
The Effect of Consuming Enzymes and Prebiotics on Body Composition and Blood Biochemical Index
To assess the effects of consuming enzymes and prebiotics on improvement of weight loss and biochemical parameters
- Trial name
- NCT04303481
- Testing
- normal diet, weight loss program kit, weight loss program kit with A. muciniphila prebiotics
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Athlete, Sedentary Behavior
Health Parameters in Soccer Players and Sedentary Individuals After Consuming a Synbiotic
The main objective of this research was to carry out an experimental study, triple blind, on the possible immunophysiological effects of a nutritional supplement (Synbiotic, Gasteel Plus®, Heel España S.A.U.), containing a…
- Trial name
- NCT04776772
- Testing
- Synbiotic complement
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Catholic University of Murcia
Osteo Arthritis Knee, Obesity
Effect of Prebiotics on Function and Pain in Patients with Osteoarthritis and Obesity
The purpose of the present study is to determine if prebiotic supplementation can, through changes in the intestinal gut microbiota, lead to improvements in knee function and physical performance and reduce knee pain in adults…
- Trial name
- NCT04172688
- Testing
- Prebiotic oligofructose-enriched inulin
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Chemotherapy-related Diarrhea
Impact of Dietary Fiber as Prebiotics on Chemotherapy-related Diarrhea in Patients With Gastrointestinal Tumors
This study evaluates longitudinal data associating changes in gut microbiota composition and diversity, defecation, performance status and adverse reactions in response to prebiotic fiber supplementation in patients with…
- Trial name
- NCT04447443
- Testing
- Prebiotic Fiber Supplement + loperamide hydrochloride capsule, Maltodextrin + loperamide hydrochloride capsule
- Where
- China
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Otitis Media
Bio-Kult Infantis® in AAD Prevention in Infants
Background: antibiotic-associated diarrhoea (AAD) is defined as an acute inflammation of the intestinal mucosa associated to the administration of antibiotics.
- Trial name
- NCT03516409
- Testing
- Biokult
- Where
- Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Probiotics International Ltd.
Prediabetes
Prebiotics, Gut Microbiota, and Cardiometabolic Health
Forty-eight prediabetic men and women (50-75 years of age) will participate in a 6-week feeding study in which they will randomized to receive either 10 g/day of inulin or placebo.
- Trial name
- NCT02346838
- Testing
- Inulin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Virginia Polytechnic Institute and State University
Prebiotics, Aged
Prebiotic Supplementation and Intestinal Barrier Function in Elderly: a RCT
The investigators aim was to assess whether 6 weeks of oral intake of the wheat-derived prebiotic fiber arabinoxylan or oat-derived beta-glucan could improve intestinal barrier function against drug-induced barrier disruption in…
- Trial name
- NCT03336385
- Testing
- Naxus, Oatwell
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Osteopenia, Postmenopausal Osteopenia
Design and Development of a Novel Food Supplement for Osteoporosis Based on Gut Microbiome Mechanisms
It is well proven that the intestinal microbe regulates bone metabolism by the absorption of calcium and other metallic trace elements.
- Trial name
- OSTEOME (NCT05421819)
- Testing
- Calcium and vitamin D supplement, Calcium, vitamin D and prebiotic supplement, Calcium, vitamin D and flavonoid supplement
- Where
- Greece
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Healthy
Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement
Randomized, Crossover, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with Daily Food Log, Stool Samples, Blood Draws, and Validated Questionnaires (GSRS, Bristol stool chart, and DQLQ) with Oral Dietary Supplement
- Trial name
- NCT06794619
- Testing
- Dietary Supplement with actives
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Gut Microbiota, Gastrointestinal Symptoms
The Effects Of HMO On The Faecal Microbiota And On Gastrointestinal Symptoms In Healthy Volunteers
The study is a randomised, placebo-controlled, double-blind, parallel, dose-finding study with healthy volunteers. A total of 100 male and female volunteers will be included.
- Trial name
- HMO-VOL (NCT01927900)
- Testing
- HMO, Glucose
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Glycom A/S
Menopause
The BALANCE Study - Improving Glucose Control Through Prebiotic Gut Health Drink in Postmenopausal Women
The menopausal transition is associated with a decline in oestrogen levels, contributing to adverse metabolic changes including increased central adiposity, systemic inflammation, and insulin resistance.
- Trial name
- BALANCE (NCT07565675)
- Testing
- ió everyday (a prebiotic- enriched gut health drink containing inulin)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Healthy
Effect of Prebiotic Intake on Gut Microbiota in Healthy Adults
In recent years, the importance of the gut microbiota to human health has been demonstrated. In adulthood, the microbial profile is relatively stable, yet can be transiently altered by factors such as diet or antibiotic…
- Trial name
- NCT03042494
- Testing
- Control, Prebiotic
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy
Effect of Fructose on Colonic Microflora
Fructose is the principal carbohydrate in fruits and is added to many food products. This 6 carbon sugar is associated with a number of ill effects, like promotion of high triglycerides,precipitation of gout in men,possible…
- Trial name
- MEF (NCT00775567)
- Testing
- Fructose powder
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Healthy
Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects
The purpose of the study is to evaluate the effects of arabinoxylan-oligosaccharides (AXOS) on the colonic metabolism and microbial composition, and to compare these effects with the reference prebiotic fructo-oligosaccharide…
- Trial name
- NCT00853034
- Testing
- FOS-IN, AXOS
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obesity
Effect of Prebiotic and Synbiotic Supplementation in Individuals Undergoing Roux-en-y Gastric Bypass.
The study will recruit patients submitted to bariatric surgery. Individuals will be supplemented with 6g/day of prebiotic or synbiotic or placebo (maltodextrin) for 15 days.
- Trial name
- NCT02158676
- Testing
- Prebiotic, Synbiotic
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Universidade Federal de Santa Catarina
Sleep Disturbance, Fatigue Syndrome, Chronic
Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation
Certain classical formulas in traditional Chinese medicine and dietary prebiotics have demonstrated beneficial effects on various aspects of suboptimal health status in previous studies.
- Conditions
- Sleep Disturbance, Fatigue Syndrome, Chronic, Endocrine Disorder, Glucose Metabolism Disorder
- Trial name
- NCT07774897
- Testing
- Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Galactooligosaccharides 2.0g
- Where
- 6 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province