Clinical trials: Prediction
Infertility
Study Evaluating the Timing of Intrauterine Insemination in Relation to Positive Home Ovulation Prediction Kit
The aim of this study is to assess the impact of the timing of intrauterine insemination (IUI) in relation to the natural surge of luteinizing hormone (LH), as detected by home ovulation predictor kits, on pregnancy rates per…
- Trial name
- NCT02294773
- Testing
- Intrauterine Insemination, Clomiphene, Letrozole
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Midwest Fertility Specialists
Postherpetic Neuralgia
Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia
The primary objective is to explore whether sensory symptom cluster analysis is useful for predicting treatment response in Postherpetic Neuralgia.
- Trial name
- NCT01603394
- Testing
- pregabalin
- Where
- 9 sites in United States, Austria and 2 more
- Volunteers
- 9 people
- Sponsor
- Pfizer
Preeclampsia
Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Preeclampsia is one of the most common complications of pregnancy and is characterized by high blood pressure and protein in the urine. This can cause problems in the second half of pregnancy for both the mother and fetus.
- Trial name
- CAPPS (NCT00135707)
- Testing
- Dietary Supplement/Vitamins
- Where
- 16 sites in United States
- Volunteers
- 10,154 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Respiratory Depression
PRediction of Opioid-induced Respiratory Depression In Patients Monitored by capnoGraphY
PRODIGY is a prospective, multi-center, post-market, international cohort study. The primary objective of this study is to derive a score to identify subjects at risk to have respiratory depression (RD) episodes in patients…
- Trial name
- PRODIGY (NCT02811302)
- Testing
- Capnostream Monitor
- Where
- 16 sites in United States, France and 5 more
- Volunteers
- 1,495 people
- Sponsor
- Medtronic - MITG
Axial Spondyloarthritis
Novel MRI ANd Biomarkers in GOlimumab-treated Patients With Axial Spondyloarthritis
The study investigates different criteria for remission based on MRI and circulating biomarkers for inflammation, cartilage, connective tissue and bone turnover in patients with axial spondyloarthritis treated with Golimumab.
- Trial name
- MANGO (NCT02011386)
- Testing
- Treatment
- Where
- 6 sites in Denmark
- Volunteers
- 53 people
- Sponsor
- Professor Mikkel Østergaard
Human Gastrointestinal Physiology Data
Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment
In vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study was to evaluate the in vivo drug dissolution and systemic absorption of the BCS Class IIa drug ibuprofen under…
- Trial name
- NCT02806869
- Testing
- Single dose of ibuprofen (800 mg tablet), Pulmocare, two 8.0 oz (236.6 mL) cans
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral
Acetazolamide Challenge With Perfusion in the Prediction of Cerebral Vasospasm
The investigators propose a technique using cone beam CT perfusion (CBCTP) imaging with an acetazolamide challenge as a potential diagnostic tool to detect a defect in cerebral autoregulation at a time when it has not yet caused…
- Trial name
- NCT03377049
- Testing
- Acetazolamide
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Wisconsin, Madison
Shortness of Breath Episode, Tachycardia
Verification of Prediction Algorithm
Prospective observational clinical study to verify an algorithm used to predict cardiopulmonary events in patients presenting to the emergency department.
- Conditions
- Shortness of Breath Episode, Tachycardia, Bradycardia, Difficulty Breathing
- Trial name
- VPAC (NCT02863666)
- Where
- 3 sites in United States, Belgium
- Volunteers
- 673 people
- Sponsor
- Zoll Medical Corporation
Hypertrophic Cardiomyopathy, Sudden Cardiac Death
PRecIsion Medicine in CardiomyopathY
This is a retrospective cohort study of pediatric hypertrophic cardiomyopathy (HCM) patients using chart and registry review methodology.
- Trial name
- PRIMaCY (NCT04036799)
- Volunteers
- 572 people
- Sponsor
- The Hospital for Sick Children
Acute Myeloid Leukemia
Ph I Study of Alvocidib and Cytarabine/Daunorubicin (7+3) in Patients With Newly Diagnosed Acute Myeloid Leukemia (AML).
The purpose of this Phase I study is to determine the safety and tolerability including the maximum dose (MTD) and dose-limiting toxicities (DLTs) of alvocidib when administered over a range of doses on Days 1-3 followed by…
- Trial name
- NCT03298984
- Testing
- Alvocidib, Cytarabine, Daunorubicin
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Sumitomo Pharma America, Inc.
Acute Myocardial Infarction
CARISMA : Cardiac Arrhythmias and Risk Stratification After MyoCardial Infarction
The purpose of this study is to assess the incidence of tachy- and bradyarrhythmic episodes in patients with acute myocardial infarction with depressed ventricular function and to determine the predictive value of several…
- Trial name
- NCT00145119
- Where
- Netherlands
- Volunteers
- 312 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Injury Leg
Sensors Prediction Study
The purpose of this study is to test whether measures of balance and agility can help predict if a Service Member may be at risk for an injury to their legs before beginning their school and training.
- Trial name
- NCT04541992
- Where
- United States
- Volunteers
- 1,891 people, healthy volunteers welcome
- Sponsor
- University of Miami
Difficult Airway
STorz Against Glidescope Effectiveness
This study evaluates success rates of tracheal intubation (passing a breathing tube)for patients who may be more challenging to intubate while utilizing one of two devices that facilitate placement of the tube with video…
- Trial name
- STAGE (NCT01632683)
- Testing
- C-MAC, Glidescope
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Esophageal Cancer, Non-small Cell Lung Cancer
Early Prediction of Pathology Response of Chemoradiotherapy With FLT PET
The goal of this research study is to learn if a new type of PET scan (18F-FLT) can help to better detect changes of tumor growth rate (or how active) in esophagus cancer and lung cancer Researchers will study at what time during…
- Trial name
- NCT01065818
- Testing
- Fluoro-L-Thymidine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Columbia University
Cataract
Randomized Trial Comparing Prediction Accuracy of Two Swept Source Optical Coherence Tomography Biometers
To assess if the Alcon Argos Biometer utilizing the Barrett Universal II formula for IOL calculations can give a non-inferior outcome when compared to the Zeiss IOL master 700 utilizing the (PCA) with the Barrett Universal II…
- Trial name
- NCT05748275
- Testing
- Argos, IOLMaster 700
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Multack Eye Care
Concussions, PCS
Predicting Persistent Postconcussive Problems in Pediatrics (5P)
Concussion, a mild traumatic injury common in children and adolescents, is a complex pathophysiological process affecting the brain.
- Trial name
- 5P (NCT01873287)
- Where
- 9 sites in Canada
- Volunteers
- 3,063 people
- Sponsor
- Children's Hospital of Eastern Ontario
Cataracts
Low Cylinder Toric
Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).
- Trial name
- NCT00732030
- Testing
- Toric IOL (SN60T3)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alcon Research
Healthy Lifestyle
Correlation of Several Formulas to Evaluate Insulin Sensitivity With the Predicted M Index
Recently, an index based on the oral insulin sensitivity index with glucose (OGIS) has been proposed in combination with anthropometric variables, called PREDIcted M (PREDIM), however, there is no evidence of the correlation of…
- Trial name
- NCT04010370
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7
Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC
This phase II trial studies how well panitumumab, carboplatin and paclitaxel work in treating patients with newly diagnosed triple negative breast cancer that is limited to the breast and possibly to the nearby lymph nodes…
- Conditions
- Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7, Stage II Breast Cancer AJCC v6 and v7
- Trial name
- NCT02593175
- Testing
- Carboplatin, Paclitaxel, Panitumumab
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- M.D. Anderson Cancer Center
Chemotherapy-induced Nausea and Vomiting
Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)
MyRisk: Efficacy and safety evaluation of oral Akynzeo® in patients receiving MEC at high risk of developing CINV based on a prediction tool. A multinational and multicenter study.
- Trial name
- CINV (NCT04817189)
- Testing
- NEPA (300mg netupitant/0.5mg palonosetron), Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV), Dexamethasone, 8 mg (oral) or equivalent IV dose
- Where
- 19 sites in China, Czechia and 5 more
- Volunteers
- 414 people
- Sponsor
- Helsinn Healthcare SA