Clinical trials: Prediction Model
Breast, Breast Cancer
Clinical Translation Research on a Multi-omics Breast Cancer Distant Metastasis Prediction Model Empowered by Artificial Intelligence
Breast cancer is one of the most common malignancies in women worldwide, and distant metastasis is the main cause of poor prognosis and death.
- Conditions
- Breast, Breast Cancer, Pathology
- Trial name
- COMPASS-BC (NCT07252986)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Schizophrenia
Risk Prediction Model of Cardiovascular Events in Patients With Schizophrenia
Schizophrenia is a serious mental illness that has a great impact on social function. Studies have evidenced that schizophrenia patients live 10-20 years less than general population.It mainly dues to high cardiovascular risk.
- Trial name
- NCT05498571
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shanghai Mental Health Center
Heart Block, Risk Factor
New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients
This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.
- Trial name
- NCT06119009
- Testing
- non interventions
- Volunteers
- 281,497 people
- Sponsor
- Chinese PLA General Hospital
Lung Cancer, Nonsmall Cell
Prediction Model of ICIs Combined With Chemotherapy in Advanced NSCLC
The reliable predictive markers to identify which patients with advanced non-small cell lung cancer tumors will achieve durable clinical benefit for chemo-immunotherapy are needed.
- Trial name
- NCT05725915
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Beijing Red Clove Public Welfare Development Center
Clear Renal Cell Cancer (< 7cm Size)
Development and Evaluation of High Risk Group Prediction Model in T1 Stage Renal Cell Cancer Using Molecular Biomarkers
For the appropriate individualized treatment of T1-stage renal cell carcinoma with heterogeneous biological features, the expression of PBRM1, SETD2, BAP1, KDM5C and the newly proposed FOXC2 and CLIP4, are compared with clinical…
- Trial name
- NCT03694912
- Testing
- Partial or radical nephrectomy
- Where
- South Korea
- Volunteers
- 426 people
- Sponsor
- Yonsei University
Chronic Postsurgical Pain, Acute Post Operative Pain
Prediction of Chronic Postsurgical Pain in Adults
This research will be a prospective single-centre observational cohort study in Denmark spanning approximately one year. The objective of this study is to develop a clinically applicable and generalizable prediction model for…
- Trial name
- NCT04866147
- Testing
- Cardiothoracic surgery, Breast surgery, Gastrointestinal surgery
- Where
- 2 sites in Denmark
- Volunteers
- 1,522 people
- Sponsor
- University of Aarhus
Breast Neoplasms
Breast Cancer Chemotherapy Risk Prediction Mathematical Model
This is a cohort study. This study is to develop a predictive model of the side effects after chemotherapy, exploreing the potential risk factors of the side effects such as myelosuppression and chemotherapy realted vomit after…
- Trial name
- BCCRPMM (NCT02547545)
- Where
- China
- Volunteers
- 795 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Predictive Model
A Prediction Model of Postoperative Anxiety Symptom in Elderly Patients Undergoing Major Noncardiac Surgery
A multicentre, prospective observational study to develop and validate a predictive model for postoperative anxiety symptoms in elderly Chinese patients undergoing non-cardiac major surgery.
- Trial name
- NCT06641986
- Where
- China
- Volunteers
- 5,551 people
- Sponsor
- Chinese PLA General Hospital
Stroke
Prediction of Gait After Stroke; an External Validation
The aim of this observational study is to perform a temporal and geographical external validation of the EPOS (Early Prediction of Outcome after Stroke) model for the prediction of independent gait after stroke.
- Trial name
- NCT06438770
- Where
- Switzerland
- Volunteers
- 136 people
- Sponsor
- Kantonsspital Winterthur KSW
Colorectal Cancer
Predicting and Addressing Colonoscopy in Safety Net Settings
The prospective cohort study will evaluate the effectiveness of patient navigation in community health center settings. The investigators will collaborate with the advisory board, composed of key clinicians and patients…
- Trial name
- PRECISE (NCT03925883)
- Testing
- Patient navigation
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Peripheral Arterial Disease
Construction and Empirical Research of a Risk Prediction Model for Preventing Lower Extremity Arteriosclerosis Obliterans in Diabetic Patients Based on the HAPA Model
In this study, Logistic regression analysis was used to construct a risk prediction model for ASO in diabetic patients. Guided by the HAPA model, a nursing intervention plan for preventing ASO in diabetic patients was constructed…
- Trial name
- NCT07881588
- Testing
- Routine Care, Experimental group intervention
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Unruptured Cerebral Aneurysm, Artificial Intelligence (AI)
AI Models for Cerebral Aneurysms Segmentation, Detection and Stability Prediction
Aneurysmal subarachnoid hemorrhage (SAH) is one of the critical diseases that severely threaten human health, with a clinical mortality rate reaching as high as 30%.
- Conditions
- Unruptured Cerebral Aneurysm, Artificial Intelligence (AI), Subarachnoid Hemorrhage, Aneurysmal, Magnetic Resonance Angiography
- Trial name
- AI-CARE (NCT06766422)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Gastric Cancer
CT Imaging and Clinical Features to Predict Outcomes in Patients With Gastric Cancer
The goal of this prospective observational study is to evaluate how well a previously developed prediction model can estimate outcomes in adults with gastric cancer.
- Trial name
- NCT07776067
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Emergency Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after emergency surgery.
- Trial name
- NCT04926038
- Where
- 5 sites in China
- Volunteers
- 200,000 people
- Sponsor
- Huazhong University of Science and Technology
Psoriasis
Prediction Model for Osteopenia in Patients With Psoriasis
This study aims to develop a clinical prediction model for osteopenia in patients with psoriasis. By retrospectively analyzing demographic, laboratory, and lifestyle variables, the investigators will identify risk factors…
- Trial name
- NCT07112755
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongli Yu
Colorectal Cancer, Peritoneal Metastases
Development and Validation of a PSN-AI Prediction Model
Heterogeneity concerning survival in synchronous peritoneal metastasis from patients with colorectal cancer exists, thereby further classification is urgently required.
- Trial name
- PSN-AI (NCT06231524)
- Testing
- Analyse pathologic slides
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Alpha-1-antitrypsin Deficiency, Emphysema
Development of a Prediction Score for the Occurrence of Death or Lung Transplantation in Patients With Emphysema Secondary to Alpha-1-anti-tripsin Deficiency
Emphysema linked to alpha-1-antitrypsin deficiency (DAAT): towards a better prediction of risks Emphysema caused by alpha-1-antitrypsin deficiency (DAAT) is a rare genetic disorder that can lead to serious complications, such as…
- Conditions
- Alpha-1-antitrypsin Deficiency, Emphysema, Artificial Intelligence (AI), Predictive Learning Models
- Trial name
- FLARE (NCT07715617)
- Where
- 4 sites in France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Bordeaux
Hypertension
A Cluster-Randomized Trial of a Hypertension Risk Model-Based Precision Intervention in High-Risk Adults in Shunyi District
This community cluster-randomized controlled trial aims to evaluate the effectiveness of a hypertension risk model-based precision intervention among adults at high risk of developing hypertension in Shunyi District, Beijing…
- Trial name
- NCT07804420
- Testing
- Hypertension Risk Model-Based Precision Intervention, Standard Health Education
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University
Healthy, Surgery
Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model
in healthy patients undergoing elective surgery, after a very slow induction, using Eleveld's kinetics as a reference, after loss of consciousness (LOC) and intubation, proceed to infuse propofol until 1% burst suppression ratio…
- Trial name
- Eleved PD (NCT06417645)
- Testing
- fixed propofol infusion 15 mg/kg/h until 1% BSR (burst suppression ratio)
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute
Repeated Examinations for Typing Pulmonary Embolism
PURPOSE The two related purposes of the RE-TyPE study are: 1. To improve understanding of the early clinical course of intermediate-high risk pulmonary embolism and its association with outcome and 2.
- Conditions
- Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute, Pulmonary Embolism With Acute Cor Pulmonale, Pulmonary Embolism With Right Ventricle Enlargement
- Trial name
- RE-TyPE (NCT07491094)
- Where
- 3 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Sahlgrenska University Hospital