Clinical trials: Prediction Model
HIV Infections, Preexposure Prophylaxis (PrEP)
Clinical Decision Support for PrEP
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the federal initiative to end the HIV epidemic. However, healthcare providers lack tools to identify patients who are at increased risk for HIV infection and…
- Trial name
- PrEDICT (NCT05245201)
- Testing
- Standard of care, Clinical decision support for PrEP
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Postoperative Pain
Prospective External Validation of an Early Prediction Model for Adverse Postoperative Pain Trajectories After Orthopedic Surgery
This prospective observational study will externally validate a previously developed and locked prediction model for identifying adult patients at risk of adverse postoperative pain trajectories after elective orthopedic surgery.
- Trial name
- NCT07846878
- Testing
- Elective Orthopedic Surgery
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Obstetric Labor Complications
Amniotic Fluid Analysis
This is a prospective study that will aid in ensuring the feasibility of timely and correct aspiration of amniotic fluid by study research team that include the clinical team taking care of the patient during her labor, timely…
- Trial name
- NCT06131684
- Testing
- Intrauterine pressure catheter (IUPC) present, Intrauterine pressure catheter (IUPC) absent
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Stroke
Risk Prediction of Carotid Endarterectomy by Vascular Ultrasound Evaluation
Carotid endarterectomy (CEA) is one of the surgical treatment methods for the reconstruction of arterial stenosis or occlusion. Perioperative stroke, cerebral hemorrhage,hyperperfusion syndrome and death are main complications of…
- Trial name
- NCT03785626
- Testing
- CEA surgery
- Where
- China
- Volunteers
- 1,498 people
- Sponsor
- Xuanwu Hospital, Beijing
Obstructive Sleep Apnea
Adherence Risk Indicator Validation Study
While continuous positive airway pressure (CPAP) is the gold standard treatment of obstructive sleep apnea (OSA), this therapy is often discontinued or not used optimally.
- Trial name
- ARI (NCT02230085)
- Testing
- Administration of the questionnaire and monitoring of CPAP adherence
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Fisher and Paykel Healthcare
Septic Shock
A Prediction Model of 28-day Mortality in Septic Shock
This clinical study adopts the design of cohort research, selects the sepsis shock patients admitted to our hospital ICU as the research object, takes the 28-day mortality rate as the outcome index, collects the baseline data of…
- Trial name
- NCT04915625
- Where
- China
- Volunteers
- 530 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
STOMACH NEOPLASM
Prediction of Drug Response in Gastric Cancer Based on 3D Bioprinting
The therapeutic regimens for adjuvant and neoadjuvant chemotherapy in gastric cancer (GC) predominantly hinge on clinical experience.
- Trial name
- NCT06792149
- Testing
- surgical resection, Adjuvant chemotherapy, neoadjuvant therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Coronary Artery Disease
CCTA-FFR Registry for Risk Prediction
The investigators sought to investigate the prognostic implication of qualitative and quantitative plaque analysis on coronary CT angiography (CCTA) according to fractional flow reserve (FFR).
- Trial name
- NCT04037163
- Testing
- Fractional flow reserve, Coronary CT angiography
- Volunteers
- 747 people
- Sponsor
- Seoul National University Hospital
Preterm Birth, Immunologic Activity Alteration
Threatened Preterm Birth and Time of Subsequent Delivery -a Prediction Model
This study investigates immunological and clinical markers in threatened preterm birth aiming to create a prediction model for preterm birth.
- Trial name
- NCT03796949
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Rectal Adenoma
Predicting Rectal Adenoma With Canceration and Investigating Mechanism Based on Multimodal MRI and Biochemical Model
In this retrospective study is to establish a diagnostic model for rectal adenoma canceration. The model will include multimodal comprehensive HR-T2WI morphological score, IVIM functional imaging and radiomics features, and…
- Trial name
- NCT06158776
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Aiyin Li
Serious Mental Illness, Type 2 Diabetes
MetSense Pilot and Feasibility
People with serious mental illness have high risk for type 2 diabetes due to multiple risk factors, including the metabolic side effects of psychotropic medications that are used to treat these conditions.
- Trial name
- MetSenseP&F (NCT07264062)
- Testing
- MetSense Risk Flag, Usual Care
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Kaiser Permanente
Lung Cancer
Advanced Data-Aided Medicine Part Lung Cancer
Developing and validating an AI model that supports physicians in their decision process for treating lung cancer patients. This AI model needs to predict the probability of (the evolution of) the outcomes, based on clinical data…
- Trial name
- ADAMpartlung (NCT05783024)
- Testing
- Data collection
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- AZ Delta
Preterm Birth, Preterm Labor
To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis
Implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection in women with preterm labor and intact membranes
- Conditions
- Preterm Birth, Preterm Labor, Intra-amniotic Infection, Amniocentesis Affecting Fetus or Newborn
- Trial name
- OPTIM-PTL (NCT04831086)
- Testing
- Steroid Drug, Tocolytic Agents
- Where
- Spain
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Postoperative Delirium
Machine Learning Algorithm for Predicting Postoperative Delirium in Elderly Patients After Thoracic Surgery
Postoperative delirium (POD) is a common and severe complication in patients undergoing major surgery, especially in the elderly.
- Trial name
- POD (NCT06226480)
- Where
- China
- Volunteers
- 3,967 people
- Sponsor
- Affiliated Hospital of Nantong University
Heart Failure, Diagnosis
Heart Failure With Improved Ejection Fraction and Deep Learning
The aim of this study was to design a deep learning-based trained model to assist in HFimpEF diagnosis.
- Trial name
- NCT06070506
- Where
- China
- Volunteers
- 422 people
- Sponsor
- Yihui Kong
ST-segment Elevation Myocardial Infarction (STEMI)
A Prospective Multicenter Clinical Study on the Long-term Prognosis of Patients With ST-segment Elevation Myocardial Infarction Using Cardiac Magnetic Resonance Imaging.
This prospective, multicenter study was designed to develop and validate a risk prediction model for major adverse cardiovascular events (MACE) in patients with acute ST-segment elevation myocardial infarction (STEMI) based on…
- Trial name
- NCT07057492
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Chinese PLA General Hospital
COVID-19, Long COVID
CORona (COVID-19) Follow Up Study: Epidemiology, Pathophysiology, Prediction, and Communication
The CORFU study, funded by ZonMW, is a prospective, multiple, cohort study with a maximum follow-up of 24 months after COVID-19.
- Conditions
- COVID-19, Long COVID, Post COVID-19 Condition
- Trial name
- CORFU (NCT05240742)
- Testing
- no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and aggregated when possible) in 7 existing cohorts
- Where
- Netherlands
- Volunteers
- 4,291 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Trigeminal Neuralgia (TN)
Developing a Clinical Prediction Model for Adverse Outcomes in Percutaneous Trigeminal Ganglion Balloon Compression
This clinical study aims to investigate adverse outcomes following percutaneous balloon compression (PBC) of the trigeminal ganglion, establish a predictive model, and assess the probability of postoperative complications.The…
- Trial name
- NCT06998420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Nantong University
Patients With Locally Advanced Carcinoma of the Stomach and Oesophagogastric Junction
Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer
Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.
- Trial name
- RADI-S (NCT06044961)
- Testing
- CT scan
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Kidney Injury, Liver Transplantation
Development and Validation of a Clinical Risk Prediction Model for Early Acute Kidney Injury Within 48 Hours After Liver Transplantation
Acute kidney injury (AKI) is a common complication after liver transplantation, with an incidence of 12.7-95%. The occurrence of acute kidney injury after transplantation is related to the poor prognosis of patients, which…
- Conditions
- Acute Kidney Injury, Liver Transplantation, Model
- Trial name
- NCT06750770
- Testing
- KDIGO CRITERIA
- Where
- China
- Volunteers
- 453 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital