Clinical trials: Prediction Model
Breast Cancer
MRI-based Approaches for Multi-parametric Model to Early Predict Pathological Complete Response to Neoadjuvant Therapy in Breast Cancer
The purpose of this clinical research is to evaluate the accuracy of a multi-parametric model based on magnetic resonance imaging (MRI) in predicting pathological complete response (pCR) after the first cycle of neoadjuvant…
- Trial name
- NeoMDSS (NCT04909554)
- Where
- China
- Volunteers
- 301 people
- Sponsor
- Guangdong Provincial People's Hospital
Octogenarian Patients With Non-metastatic Resectable Colorectal Cancer
SGA-OCRC: Prediction of 90-Day Major Adverse Postoperative Outcomes in Octogenarians With Resectable Colorectal Cancer
Octogenarian patients with colorectal cancer are a growing population with substantial heterogeneity in frailty, functional reserve, nutritional status, and comorbidity.
- Trial name
- NCT07903129
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Military Activity
Body Fat Percentage Prediction Model After Basic Combat Training on Army Candidate in Indonesia
This research is a quantitative study using the Pre-Experimental Model One-Group Pretest-Posttest Design with total sampling from the Republic of Indonesia Defense University batch 4 cadets that fullfiled criteria.
- Trial name
- NCT06134427
- Testing
- basic combat training (investigator did not design the intervention)
- Where
- Indonesia
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Liver Cancer
Development of a Risk Prediction Model for Immune-Targeted Therapy-Related Diarrhea in Patients With Hepatocellular Carcinoma Based on TCM Constitutional Types: A Prospective Cohort Study
Immune checkpoint inhibitors combined with anti-angiogenic targeted agents have become the first-line standard therapeutic regimen for advanced hepatocellular carcinoma (HCC).
- Trial name
- NCT07741903
- Volunteers
- 500 people
- Sponsor
- Affiliated Hospital of Chengde Medical University
Brachial Plexus Injury
A Multicenter External Validation of a Novel Prediction Model for Elbow Flexion Recovery After Nerve Transfer Surgery in Brachial Plexus Injuries
The goal of this observational study is to validate a risk prediction model developed for unsuccessful elbow flexion recovery after nerve transfer surgery in patients with brachial plexus injury.
- Trial name
- NCT06237270
- Testing
- Nerve transfer surgery for elbow flexion
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Siriraj Hospital
Knee Arthropathy, Hip Arthropathy
Analysis of Influencing Factors and Construction of Prediction Models of Artificial Joint Replacement in China
The project intends to analyze the epidemiological characteristics, risk factors, complications and resource utilization of artificial joint replacement in China through the inpatient data collected by the Hospital Quality…
- Conditions
- Knee Arthropathy, Hip Arthropathy, Shoulder Arthropathy, Ankle Arthropathy
- Trial name
- NCT05170321
- Where
- China
- Volunteers
- 600,000 people
- Sponsor
- Xiangya Hospital of Central South University
Swallowing Disorders
Radiation-Related Dysphagia Development Prediction Using a Two-Step Ultrasonographic Model (R-2D-2)
Radiotherapy for head and neck cancers (H\&NC) heightens the risk of swallowing disorders (SD), impacting nutrition, quality of life, and overall health, leading to increased hospitalization and mortality.
- Trial name
- R-2D-2 (NCT06387004)
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Hopital Forcilles
Postoperative Delirium, Postoperative Cognitive Dysfunction
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- CogCheck-Valid (NCT03360838)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 475 people
- Sponsor
- University Hospital, Basel, Switzerland
Papillary Thyroid Carcinoma, Thyroid Neoplasms
RET-US Study - Ultrasound-Based Prediction of RET Alterations and Lateral-Neck Metastasis in Thyroid Cancer
Why is this study being done? RET gene alterations occur in only 5-10 % of papillary thyroid cancers, but they can change how surgeons treat the disease.
- Conditions
- Papillary Thyroid Carcinoma, Thyroid Neoplasms, RET Proto-Oncogene Mutation, Lymphatic Metastasis
- Trial name
- RET-US (NCT07042984)
- Testing
- AI-Ultrasound RET Prediction
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Fujian Medical University
Severe Preeclampsia
Risk Prediction Models for Adverse Maternal and Neonatal Outcomes in Preeclampsia
This proposal describes a single centre retrospective cross-sectional study which will address the need to further develop and test statistical risk prediction models for adverse maternal and neonatal outcomes in low-resource…
- Trial name
- NCT04058405
- Testing
- Observational
- Where
- Zimbabwe
- Volunteers
- 549 people
- Sponsor
- Mpilo Central Hospital
Sepsis
Host Dysregulation-Driven Sepsis Prediction Model
The aim of this study is to identify risk factors associated with sepsis and to construct a predictive model for sepsis. This will provide an objective theoretical and empirical foundation for the diagnosis, assessment, and…
- Trial name
- NCT06523075
- Testing
- Tumor Necrosis Factor, Interleukin-1β, Interleukin-12
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
GDM
Gestational Lifestyle & Outcomes Wellness
A Multicenter Prospective Cohort Study to Identify Risk Factors and Develop a Diagnostic Prediction Model for Gestational Diabetes Mellitus, and to Evaluate the Effectiveness of Multidisciplinary Precision Health Interventions…
- Trial name
- NCT07263412
- Testing
- cgm, Behavioral Self-Monitoring of Blood Glucose, Control
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Sepsis, Burn Injury
TDAP in Burn Patients (Group 2)
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07223684
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Pre-Eclampsia
Prediction of Preeclampsia by Comprehensive Markers.
Preeclampsia is one of the most serious complications in pregnancy that causes maternal death and preterm delivery. Series studies has show that the competing risk model developed by the Fetal Maternal FouNdation in early…
- Trial name
- NCT03665623
- Where
- China
- Volunteers
- 11,741 people
- Sponsor
- Peking Union Medical College Hospital
IVF Outcomes, Prediction Models
Machine-Learning Prediction of Pregnancy Outcomes After Assisted Reproductive Treatments
The goal of this observational study is to develop and validate a machine-learning model to predict pregnancy outcomes in women with a positive pregnancy test following assisted reproductive treatment (ART), with the primary…
- Conditions
- IVF Outcomes, Prediction Models, Infertility Assisted Reproductive Technology, Live Birth
- Trial name
- NCT07855783
- Testing
- Machine-Learning Model for Prediction of Pregnancy Outcomes
- Where
- 2 sites in Croatia
- Volunteers
- 2,200 people
- Sponsor
- BetaPlus Center for Reproductive Medicine
Gastric Cancer
Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer
This study aims to develop a model to predict response to chemotherapy in gastric cancer using RNA splicing information from tumor tissue.
- Trial name
- NCT07587229
- Testing
- Observational study (no intervention)
- Where
- United States
- Volunteers
- 329 people
- Sponsor
- City of Hope Medical Center
Type 2 Diabetes
Multimodal Glucose Prediction in Type 2 Diabetes
The primary objective of this research, funded by Samsung Strategic Alliance for Research and Technology, is to develop multi-modal foundation models that integrate Continuous Glucose Monitoring (CGM) data with patient behavior…
- Trial name
- NCT07633171
- Testing
- Digital Health Data Collection System
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Delirium
With the Development of Research, New Algorithms and Technologies Have Emerged, One of Which is Machine Learning. Machine Learning Can Extract Key Factors From Vast Amounts of Data, Identify Underlying Patterns, and Predict Future Trends. In Recent Years, Machine Learning Has Been Widely Used in
The aim of this study is to construct a predictive model for postoperative delirium in elderly patients with hip fractures. The main question it answers is to construct a risk prediction model for hip fractures in the elderly…
- Trial name
- POD (NCT07121309)
- Where
- China
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Locally Advanced Cervical Cancer
A Prospective Study on the Prediction Model of Para-aortic Lymph Node Metastasis
The goal of this prospective single-arm trial is to investigate the accuracy and feasibility of the para-aortic lymph node metastasis prediction model in locally advanced cervical cancer, as well as its impact on patients'…
- Trial name
- NCT06068387
- Testing
- surgical staging
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Chongqing University Cancer Hospital
Delirium
International Validation of a Delirium Prediction Model for ICU Patients
Recently our ICU research group developed and validated a delirium prediction model in the NetherlandsThis. This model has a high predictive value.
- Trial name
- NCT01249755
- Volunteers
- 2,000 people
- Sponsor
- Radboud University Medical Center