Clinical trials: Prediction Model
Diabetes Mellitus, Pre Diabetes
Development and Validation of DM and Pre-DM Risk Prediction Model
Many DM and pre-DM remain undiagnosed. The aim is to develop and validate a risk prediction function to detect DM and pre-DM in Chinese adults aged 18-84 in primary care (PC). The objectives are to: 1.
- Trial name
- NCT04881383
- Testing
- OGTT and HbA1c
- Where
- Hong Kong
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Aplastic Anemia, Pregnancy
A Prediction Model in Pregnant Women With Aplastic Anemia
Aplastic anemia (AA) is a rare haematologic disorder characterized by bone marrow failure and pancytopenia. Its occurrence during pregnancy is exceedingly rare but poses significant risks, including maternal hemorrhage…
- Conditions
- Aplastic Anemia, Pregnancy, Prediction Model
- Trial name
- NCT07101770
- Testing
- A combined retrospective and prospective observational follow-up
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Immunotherapy, Gastric Cancer
Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors
immunotherapy，gastric cancer，rectal cancer，biomark
- Conditions
- Immunotherapy, Gastric Cancer, Rectal Cancer, Chemotherapy Effect
- Trial name
- NCT05515796
- Testing
- Terelizumab (aka Tislelizumab), CapeOx, Trastuzumab
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Breast Cancer
Quantifying Radiation-Induced Skin Reactions: Establishing the Foundation for Future Prediction Models
Breast cancer has the highest incidence rate among female cancers, and breast radiotherapy plays an essential role in the treatment of breast cancer.
- Trial name
- NCT06029231
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Soft-tissue Sarcoma, Predictive Cancer Model
The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas Patients
The goal of this clinical trial is to assess the (cost-)effectiveness of a personalised risk assessment tool (PERSARC) to increase patients' knowledge about risks and benefits of treatment options and to reduce decisional…
- Trial name
- VALUE_PERSARC (NCT05741944)
- Testing
- Care with the use of PERSARC, standard care
- Where
- 7 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Leiden University Medical Center
Frail Elderly Syndrome, Triage
The Prediction Model of Elderly Patients in Taiwan Triage and Acuity Scale
In the year of 2010, the Taiwan Ministry of Health and Welfare had implemented the 5-level Taiwan Triage and Acuity Scale(TTAS) in Taiwan emergency department. TTAS is a triage system that was modified from CTAS.
- Trial name
- NCT04862936
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Chang Gung Memorial Hospital
Oncology
Risk Scoring Model for Endometrial Cancer
A prospective cohort study to assess RHEA ( recurrent vaginal bleeding, hypertension, endometrial thickness and age) scoring model for prediction of endometrial carcinoma
- Trial name
- Cohort (NCT03298100)
- Testing
- Scoring model
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Cardiovascular Diseases, Elderly Patients
Prediction Model of Cardiac Risk for Dental Extraction in Elderly Patients With Cardiovascular Diseases
This study intends to investigate the relevant risk factors of perioperation complications or mortality in older patients with cardiac diseases undergoing teeth extraction surgery and this study aims to quantify the risk factors…
- Conditions
- Cardiovascular Diseases, Elderly Patients, Tooth Extraction
- Trial name
- NCT03211312
- Where
- China
- Volunteers
- 833 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Metastatic Hormone-Sensitive Prostate Cancer, Prostate Cancer
PSMA PET/CT-Based Multimodal Model for Predicting Response to First-Line Therapy in mHSPC.
This multicenter retrospective study developed and validated a prediction model based on PSMA PET/CT and routine clinical information to estimate early treatment response in patients with metastatic hormone-sensitive prostate…
- Trial name
- NCT07428642
- Testing
- Androgen Deprivation Therapy, Apalutamide, Enzalutamide
- Where
- China
- Volunteers
- 168 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Pregnant With Complication, Preeclampsia
Developing & Evaluating Models for Early Predicting Obstetrical Diseases in Pregnant Women by Non-invasive Prenatal Test
This is Observational study, aiming to investigate the potentiality of cffDNA and cfRNA by a non-invasive test, in combination with clinical characteristics, to establish models for early screening and predicting high-risk…
- Conditions
- Pregnant With Complication, Preeclampsia, Preterm Birth, Gestational Diabetes
- Trial name
- NCT06385366
- Where
- Vietnam
- Volunteers
- 1,105 people
- Sponsor
- Gene Solutions
Infant, Small for Gestational Age
Growth Hormone Treatment in Short Children Born Small for Gestational Age
Comparison of 2 different doses of human growth hormone treatment on change in height after 1 and 2 years of treatment.
- Trial name
- NCT00191529
- Testing
- somatropin
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Lung Cancer
Advanced Data-Aided Medicine Part Lung Cancer
Developing and validating an AI model that supports physicians in their decision process for treating lung cancer patients. This AI model needs to predict the probability of (the evolution of) the outcomes, based on clinical data…
- Trial name
- ADAMpartlung (NCT05783024)
- Testing
- Data collection
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- AZ Delta
Trigeminal Neuralgia (TN)
Developing a Clinical Prediction Model for Adverse Outcomes in Percutaneous Trigeminal Ganglion Balloon Compression
This clinical study aims to investigate adverse outcomes following percutaneous balloon compression (PBC) of the trigeminal ganglion, establish a predictive model, and assess the probability of postoperative complications.The…
- Trial name
- NCT06998420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Nantong University
Endometrial Cancer
Different Risk Stratification Models for Prediction of Lymph Node Involvement in Endometrial Carcinoma
Endometrial cancer is the most common malignant disease of the female genital tract and the seventh most common cause of cancer death in women in Western countries.
- Trial name
- NCT04120649
- Testing
- hysterectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Emergency Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after emergency surgery.
- Trial name
- NCT04926038
- Where
- 5 sites in China
- Volunteers
- 200,000 people
- Sponsor
- Huazhong University of Science and Technology
Covid19
Application of Machine Learning Based Approaches in Emergency Department to Support Clinical Decision Managing SARS-CoV-2 Infected Patients
The aim of the study is to develop a prognostic prediction model based on machine learning algorithms in patients affected by coronavirus disease 2019 (COVID-19), the prediction model will be capable to recognize patient with…
- Trial name
- NCT04825301
- Where
- Italy
- Volunteers
- 779 people
- Sponsor
- University of L'Aquila
HIV Infections, Preexposure Prophylaxis (PrEP)
Clinical Decision Support for PrEP
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the federal initiative to end the HIV epidemic. However, healthcare providers lack tools to identify patients who are at increased risk for HIV infection and…
- Trial name
- PrEDICT (NCT05245201)
- Testing
- Standard of care, Clinical decision support for PrEP
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Sarcoma
Swiss Sarcoma Network: Prediction Model for Patient Selection in Sarcoma Care
The primary significance of this project is to perform a detailed analysis to assess the diagnostics, treatment and follow-up care, to develop a prediction model for future patient selection regarding various diagnostic and…
- Trial name
- NCT04300257
- Where
- 8 sites in Switzerland
- Volunteers
- 600 people
- Sponsor
- Kantonsspital Winterthur KSW
Diabetes Mellitus, Type 2 Diabetes
Validation of Insulin Dose Prediction Model Based on Artificial Intelligence Algorithm
The present study aims to conduct a prospective controlled trial comparing an LSTM-based artificial intelligence (AI) prediction model and clinicians' experience in the efficacy and safety of blood glucose control in hospitalized…
- Trial name
- NCT07066891
- Testing
- CSII in the prediction model group, CSII in the empirical group
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Sun Yat-sen University