Clinical trials: Prediction Model
Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome
Development and Validation of a Risk Prediction Model for Cardiac Surgery-associated Acute Kidney Injury Based on the Gut-Kidney Axis, Incorporating Gut Microbiota and Their Metabolites
This is a single-center prospective observational cohort study enrolling adult patients scheduled for cardiac surgery. Multi-timepoint clinical indicators, stool samples for gut microbiota and metabolomics profiling and artery…
- Conditions
- Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome, Metabolome, Risk Assessment
- Trial name
- NCT07738796
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Peking Union Medical College Hospital
Mitral Regurgitation, Heart Failure
Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy
This observational study is to develop and validate the prediction model for functional mitral regurgitation regression in heart failure patients taking GDMT.
- Trial name
- NCT06278727
- Testing
- angiotensin-converting enzyme inhibitors/angiotensin II receptor blocker/angiotensin receptor-neprilysin inhibitor, The development of the prediction model
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Heart Failure, Heart Failure, Systolic
Predicting Heart Failure Outcomes With Biomarkers and Imaging
This study aims to develop a better model to predict one-year risk of death in patients with heart failure. We will test whether combining information from routine blood tests (like NT-proBNP) and heart scans (measuring features…
- Conditions
- Heart Failure, Heart Failure, Systolic, Heart Failure, Diastolic, Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BIOPHF (NCT07332520)
- Volunteers
- 4,000 people
- Sponsor
- Xinjiang Medical University
Delirium, Intensive Care Unit Delirium
PREdiction of DELIRium in Medical ICU Patients
In intensive care unit (ICU) patients, the ability to predict delirium may help reduce its incidence, duration, and severity. The PREdiction of DELIRium in ICU (PRE-DELIRIC) model was recently developed for this purpose.
- Trial name
- NCT04218461
- Testing
- PRE-DELIRIC model
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people
- Sponsor
- Istanbul Demiroglu Bilim University
Lymph Node Metastasis, Hepatocellular Carcinoma
A Study of Individualized Radiotherapy Based on a Prediction Model of Lymph Node Metastasis in Hepatocellular Carcinoma
Objectives: 1. To further validate the predictive efficacy of our established microRNA prediction model of HCC lymph node metastasis. 2.
- Conditions
- Lymph Node Metastasis, Hepatocellular Carcinoma, Radiotherapy
- Trial name
- NCT03416803
- Testing
- Radiotherapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Zhongshan Hospital
Schizophrenia
Transcranial Sonography and Machine Learning for Schizophrenia Identification
Schizophrenia is a serious mental illness. Doctors usually diagnose schizophrenia by talking with patients, reviewing symptoms, and using clinical assessment. In early or less typical cases, diagnosis may be difficult.
- Trial name
- TCS-ML-SZ (NCT07604129)
- Testing
- Transcranial Sonography
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Taizhou Second People's Hospital
Stomach Neoplasms, Aged
Model for Prognosis of Elderly Gastric Cancer Patients
This study aims to develop and validate a Random Survival Forest (RSF) model for predicting long-term survival in elderly patients following curative resection for gastric cancer.
- Trial name
- NCT06393153
- Where
- China
- Volunteers
- 1,202 people
- Sponsor
- Chang-Ming Huang, Prof.
Rhabdomyolysis, Death
The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score
One in three adults over 65 fall annually, with one in five remaining on the floor for greater than one hour, which is referred to as a long lie.
- Conditions
- Rhabdomyolysis, Death, Kidney Replacement Therapy, Fall Patients
- Trial name
- The REED Score (NCT07158554)
- Where
- United Kingdom
- Volunteers
- 1,161 people
- Sponsor
- University of Salford
Postoperative Pain
Prospective External Validation of an Early Prediction Model for Adverse Postoperative Pain Trajectories After Orthopedic Surgery
This prospective observational study will externally validate a previously developed and locked prediction model for identifying adult patients at risk of adverse postoperative pain trajectories after elective orthopedic surgery.
- Trial name
- NCT07846878
- Testing
- Elective Orthopedic Surgery
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Chronic Liver Disease and Cirrhosis
Real-World Validation of a Prognostic Prediction Model for Patients With Acute Exacerbations of Chronic Liver Disease
Our study is a multi-site, prospective, observational study including patients with acute exacerbations of CLD. Approximately 1500 patients from 24 hospitals in diverse regions in China will be enrolled and followed for 3 months.
- Trial name
- NCT06181448
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Genetic Disease, Pediatrics
Clinical Decision Support to Identify Pediatric Patients With Undiagnosed Genetic Disease
This study will evaluate the effectiveness of SIGHT as a clinical support system to prompt provider/patient discussion and shared decision making regarding the need for genetic testing in the form of a chromosomal microarray.
- Conditions
- Genetic Disease, Pediatrics, Predictive Model, Clinical Decision Support
- Trial name
- SIGHT (NCT06744543)
- Testing
- SIGHT Prompted Provider Message
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanderbilt University Medical Center
Severe Early Childhood Caries, Caries
Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries
This study aims to address the high prevalence and recurrence rate of severe early childhood caries (S-ECC) by breaking away from the traditional single biological factor perspective and introducing the theories of "24-hour…
- Trial name
- NCT07335744
- Testing
- questionnaire survey
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Fever, Triage
Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department
This multicenter prospective observational cohort study evaluates how well the initial triage category assigned by the Turkish Ministry of Health three-level color-coded triage system (Red-Yellow-Green) predicts serious clinical…
- Conditions
- Fever, Triage, Pediatric Emergency Medicine, Serious Bacterial Infection
- Trial name
- PEDTRIAGE (NCT07739004)
- Testing
- Ministry of Health three-level color-coded triage
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people
- Sponsor
- TC Erciyes University
Colorectal Cancer
Developing Risk Prediction Model and Testing the Effect of Dual Task Walking on Improving Cognitive Function in Patients With Colorectal Cancer
The aims of this three-year study are to explore cognitive function under different stages of colorectal cancer (CRC) and its related factors; and understand its disturbance and coping process caused by cancer-induced cognitive…
- Trial name
- NCT04490733
- Testing
- dual-task walking
- Where
- Taiwan
- Volunteers
- 355 people
- Sponsor
- National Taiwan University Hospital
Chronic Pain, Limb Fracture
Chronic Pain Predictors in Major Trauma
The goal of this observational study is to learn about who is at risk of developing chronic pain in a major trauma population with at least one limb fracture.
- Trial name
- COPE: MT (NCT07237152)
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- University of Nottingham
Difficult Intubation
A Predictive Model for Difficult Intubation
Failure in airway management is one of the most common anesthesia-related morbidity and mortality. Each individual airway assessment has limitation to predict difficult intubation.
- Trial name
- NCT02944305
- Testing
- Endotracheal intubation
- Where
- Thailand
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Carotid Stenosis, Ischemic Stroke
Comprehensive Assessment of Atherosclerotic Ischemic Stroke Risk and Development of a Prediction Model
This observational study was designed for the assessment of plaque vulnerability in patients with carotid atherosclerotic stenosis and the development of predictive models for the occurrence and recurrence of atherosclerotic…
- Trial name
- CAIS-pre (NCT06315153)
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Prolonged Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after prolonged surgery.
- Trial name
- NCT04926025
- Where
- 5 sites in China
- Volunteers
- 500,000 people
- Sponsor
- Huazhong University of Science and Technology
Cardiovascular Modeling, Aortic Coarctation
Proof of Concept of Model Based Cardiovascular Prediction
CARDIOPROOF is a proof-of-concept project that consolidates the outcomes of previous virtual physiological human (VPH) projects and checks the applicability and effectiveness of available predictive modelling and simulation…
- Conditions
- Cardiovascular Modeling, Aortic Coarctation, Aortic Valve Disease, Cardiovascular MRI
- Trial name
- NCT02591940
- Testing
- Surgery or Treatment by Heart Catheter
- Volunteers
- 140 people
- Sponsor
- German Heart Institute
Trapeziometacarpal Osteoarthritis, Thumb Osteoarthritis
ICF-Based Biopsychosocial Assessment With AI-Assisted Profile Prediction: Trapeziometacarpal Osteoarthritis Model
Trapeziometacarpal osteoarthritis (TMC OA) is a common condition affecting the base of the thumb that causes pain, weakness, and difficulty with daily hand use.
- Conditions
- Trapeziometacarpal Osteoarthritis, Thumb Osteoarthritis, Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
- Trial name
- ICF (NCT07458971)
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Hacettepe University