Clinical trials: Prediction Model
Immune Thrombocytopenia, ITP
Machine-learning Based Prediction Model in Primary Immune Thrombocytopenia
This study developed the first prediction model for risk of critical ITP bleeds for ITP inpatients using a novel machine learning algorithm.
- Trial name
- NCT05116423
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Breast Neoplasms
Development of a Multi-omics Prediction Model for Immunotherapy Response in Triple-Negative Breast Cancer Subtypes
This study aims to collect clinical samples from breast cancer patients who have undergone or are expected to undergo immunotherapy at our institution.
- Trial name
- NCT06833723
- Testing
- Retrospective Data Collection and Analysis
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery
This observational study aims to develop a predictive model for the occurrence of new-onset stress urinary incontinence (SUI) after pelvic organ prolapse (POP) repair surgery in women.
- Trial name
- NCT07601282
- Testing
- Telephone follow-up
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Heart Failure, Pulmonary Arterial Hypertension
Non-invasive Pulmonary Artery Prediction
Cardiac remote monitoring devices have expanded our ability to track physiological changes used in the diagnosis and management of patients with cardiac disease.
- Trial name
- ADOPTS (NCT05622695)
- Testing
- catheterization
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Silverleaf Medical Sciences INC
Swallowing Disorders
Radiation-Related Dysphagia Development Prediction Using a Two-Step Ultrasonographic Model (R-2D-2)
Radiotherapy for head and neck cancers (H\&NC) heightens the risk of swallowing disorders (SD), impacting nutrition, quality of life, and overall health, leading to increased hospitalization and mortality.
- Trial name
- R-2D-2 (NCT06387004)
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Hopital Forcilles
Muscle Injury, Sprains and Strains
The Role of Periodic Health Examination in Determining Indirect Muscle Injury Risk in Elite Football (Soccer)
Preseason periodic health examination (PHE) is used routinely in elite football (soccer) and can be used to inform injury prevention strategies. Indirect muscle injuries (IMI) are a considerable burden to elite teams.
- Trial name
- NCT03782389
- Testing
- Preseason Periodic Health Examination Completion
- Volunteers
- 321 people
- Sponsor
- Manchester United Football Club
Rheumatoid Arthritis
A Specification Clinical Application Research of Tripterygium Wilfordii Treating Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an autoimmune disease that results in a chronic inflammatory disorder that may affect many synovial joints, and may cause serious disability.
- Trial name
- NCT03337815
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Headache, Comorbidities
Headache Registration and Followup Initiated by Tongji Hospital, HUST
Headache is one of the most common chief complaints in clinical practice, with a high global prevalence rate. It may originate from a primary headache disorder or manifest as a clinical symptom of various diseases due to the…
- Trial name
- HEALTH (NCT07269561)
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Tongji Hospital
Cardiovascular Diseases, Atherosclerosis
The AI-CAC Model for Subclinical Atherosclerosis Detection on Chest X-ray
The AI-CAC model is an artificial intelligence system capable of assessing the presence of subclinical atherosclerosis on a simple chest radiograph.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Coronary Artery Calcification
- Trial name
- AI-CAC-PVS (NCT06301009)
- Testing
- AI-CAC score
- Volunteers
- 500 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Renal Neoplasms, Pathology
Optimising Renal Tumour Management Through Artificial Intelligence Modules
The goal of this observational study is to improve the management of people with renal tumour by multimodal artificial intelligence(AI). It will also measure the accuracy of the predictions from AI models.
- Conditions
- Renal Neoplasms, Pathology, Renal Cell Cancer
- Trial name
- NCT06714916
- Where
- China
- Volunteers
- 2,100 people
- Sponsor
- Shao Pengfei
Pregnancy Complications, Delivery Complications
CoPPer Study - Complications of Polycystic Ovary Syndrome (PCOS) Pregnancy: Evaluating Risk
The CoPPer study is a follow-up study of women diagnosed with Polycystic Ovary Syndrome (PCOS). Women will be included pre-conceptional and followed-up until after delivery.
- Conditions
- Pregnancy Complications, Delivery Complications, Neonatal Complications
- Trial name
- CoPPer (NCT00821379)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- UMC Utrecht
Risk Factors
Establishment of Risk Factors Model of Drug-induced Coagulation Disorder Caused by Cefoperazone Sulbactam Sodium
The incidence rate of drug-induced blood diseases accounts for about 10% of all drug-induced diseases, most of which are serious at the time of onset, and the mortality rate can be as high as 32.5%.
- Trial name
- NCT05535309
- Testing
- cefoperazone sulbactam sodium
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Qianfoshan Hospital
Cancer, Immunotherapy
Exploring Physical and Psychological Needs and Quality of Life in Patients With Advanced Cancer Receiving Immunotherapy
During the immune checkpoint inhibitor therapy (ICIT), most of the patients stay at home, but there is lacking of the studies to explore their physical and psychological distress, financial toxicity, care needs, and quality of…
- Conditions
- Cancer, Immunotherapy, IrAE, Distress, Emotional
- Trial name
- NCT06461780
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Infant, Small for Gestational Age
Growth Hormone Treatment in Short Children Born Small for Gestational Age
Comparison of 2 different doses of human growth hormone treatment on change in height after 1 and 2 years of treatment.
- Trial name
- NCT00191529
- Testing
- somatropin
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Arthritis Knee, Anesthesia
Prediction Model of Acute Postoperative Pain in Bilateral Total Knee Replacement Arthroplasty Patient
This study aims to predict risk factors of acute postoperative pain of the patients undergoing Total Knee Replacement Arthroplasty(TKRA).
- Conditions
- Arthritis Knee, Anesthesia, Arthropathy of Knee
- Trial name
- NCT03765723
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
VHL Syndrome, Renal Cell Carcinoma
Establishment of a Multidimensional Prediction Model for the Natural Course of VHL Disease-related Renal Cell Carcinoma
VHL syndrome is a rare hereditary tumor syndrome caused by mutation of tumor suppressor gene VHL. One of the most important clinical manifestations and main cause of death is VHL-related renal cell carcinoma (RCC).
- Trial name
- NCT06391879
- Testing
- Single cell sequencing, whole genome and metabolomic sequencing
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy
Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository
The Hearts in Rhythm Organization (HiRO) is a national network of Canadian researchers/clinicians, working towards a better understanding of the rare genetic causes of sudden cardiac death (SCD).
- Conditions
- Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy, Familial Hypertrophic Cardiomyopathy, Cardiomyopathies
- Trial name
- HiRO-HCM (NCT05100420)
- Where
- 17 sites in Canada
- Volunteers
- 2,000 people
- Sponsor
- Montreal Heart Institute
Cancer, Neoadjuvant Therapy
Development and Validation of a Multimodal Fusion Artificial Intelligence Model for Predicting the Efficacy of Neoadjuvant Treatment of Bladder Cancer
This study is a multi-center observational study without interventions, including the construction of an AI predictive model, with retrospective and prospective testing.
- Trial name
- NCT06909643
- Testing
- Artificial intelligence (AI)-based predictive model
- Where
- China
- Volunteers
- 469 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Delirium
PROfylactic Haloperidol in Patients Defined as High Risk for DElirium With Delirium Risk mOdel
The hospital pharmacy at the Zuyderland Medical Centre developed the DElirium MOdel (DEMO) to predict which patients are at risk of developing a delirium in patients aged 60 or older.
- Trial name
- PRODEO (NCT03199950)
- Testing
- Haloperidol
- Where
- Netherlands
- Volunteers
- 1,366 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Recurrent Implantation Failure
Efficacy of a Non-Invasive Endometrial Receptivity Prediction Model Based on Peripheral Blood miRNA Signatures During the Peri-Implantation Period in Improving IVF Outcomes in Patients With Unexplained RIF
The goal of this clinical trial aims to investigate whether a non-invasive implantation window prediction model, constructed based on characteristic changes in peripheral blood miRNAs during the peri-implantation period, can…
- Trial name
- RIF (NCT07363018)
- Testing
- Non-invasive endometrial receptivity prediction model guides personalized embryo transfer for patients with recurrent implantation failure (RIF).
- Volunteers
- 546 people
- Sponsor
- Tang-Du Hospital