Clinical trials: Prediction of Disease Progression
Non-small Cell Lung Cancer
Therapeutic Resistance Prediction of Tyrosine Kinase Inhibitors
The investigators propose a non-invasive prognostic tool for TKIs resistance in patients with stage IV EGFR-mutant non-small cell lung cancer (NSCLC) by computed tomography phenotypic features, which can be conveniently…
- Trial name
- NCT02851329
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Alzheimer Disease, Chronic Traumatic Encephalopathy
Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
CMK-0301 is a multi-site, randomized clinical trial to evaluate the safety and efficacy of [F-18]Flornaptitril-PET (F-18 FNT-PET) for the prediction of clinical progression of Mild Cognitive Impairment (MCI) with either Suspected…
- Trial name
- NCT06254469
- Testing
- [F-18]Flornaptitril
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- CereMark Pharma, LLC
Tumor, Lung Cancer
The Impact of M1/M2 Tumor Associated Macrophage (TAM) Polarization on Cancer Progression and Prognosis Prediction
The purpose of this study is to evaluate the correlation between M1/M2 phenotype of tumor associated macrophage (TAM) in lung cancer patients and clinical outcome.
- Trial name
- NCT00690261
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Clinical Deterioration, Hemodynamic Instability
Early Identification of Clinical Deterioration Using a Wearable Monitoring Device
This study aims to provide myriad of physiological parameters in patients admitted in an internal medicine department, and which are defined as being in an increased risk of clinical deterioration within the first 72-hours after…
- Trial name
- NCT04220359
- Testing
- non-invasive monitoring
- Where
- Israel
- Volunteers
- 410 people
- Sponsor
- Biobeat Technologies Ltd.
Kidney Transplant Failure, Kidney Function Issue
Trajectories of Glomerular Filtration Rate and Progression to End Stage Renal Disease After Kidney Transplantation
The gold standard for characterizing chronic kidney disease (CKD) is the glomerular filtration rate (GFR), which is commonly estimated in both native and transplanted kidneys for patient monitoring and therapeutic management and…
- Trial name
- TRAJAKT (NCT04226859)
- Testing
- No intervention
- Where
- 15 sites in United States, Belgium and 2 more
- Volunteers
- 14,000 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
Coronary Atherosclerosis, Acute Coronary Syndrome
Prediction of Progression of Coronary Artery Disease (CAD) Using Vascular Profiling of Shear Stress and Wall Morphology
Although atherosclerosis is a systemic disease, its manifestations are focal and eccentric, and each coronary obstruction progresses, regresses, or remains quiescent in an independent manner.
- Conditions
- Coronary Atherosclerosis, Acute Coronary Syndrome, Percutaneous Coronary Intervention, Endothelial Shear Stress
- Trial name
- PREDICTION (NCT01316159)
- Where
- United States
- Volunteers
- 506 people
- Sponsor
- Brigham and Women's Hospital
Prediction of Disease Progression, Multiple Sclerosis
Disease Progression in ms
Demographic and clinical data will be obtained from people with MS. Based on this data, the progression of the disease will be predicted with artificial intelligence.
- Trial name
- NCT07292116
- Volunteers
- 53 people
- Sponsor
- Hüseyin Bektaş
Parkinson Disease
A Study of the Efficacy of IAMT as an Assessment Tool for Prediction of Progression of Parkinson's Disease
The primary objective of this proposal is to examine the efficacy of Improvised Active Music Therapy (IAMT) sessions as an early novel tool for cognitive and motor assessment for individuals with Parkinson's Disease (PD) in…
- Trial name
- Music Therapy (NCT05971459)
- Testing
- Improvised Active Music Therapy
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Coronary Artery Disease
Prediction of Atherosclerotic Plaque Progression
To predict coronary atherosclerosis progression in patients with acute coronary syndrome by the use of intracoronary imaging methods.
- Trial name
- PPP (NCT05424705)
- Testing
- OCT, NIRS
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Na Homolce Hospital
Pulmonary Subsolid Nodules, Ground-Glass Nodules
Virtual Follow-up Prediction of Subsolid Pulmonary Nodules: A Prospective Silent Reader Study
The goal of this prospective, non-interventional study is to evaluate the predictive performance and potential clinical utility of an artificial intelligence (AI)-based virtual follow-up framework for incidentally detected…
- Trial name
- VF-PN (NCT07900815)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sepsis, Infection
Evaluation of the Heparin Binding Protein Levels in Sepsis
Present criteria used to define sepsis are non-specific, making it difficult to both distinguish sepsis from other diseases and to predict which patients are likely to become more severely ill.
- Conditions
- Sepsis, Infection, Septic Shock
- Trial name
- HBP (NCT02533011)
- Testing
- HBP lab test
- Where
- United States
- Volunteers
- 1,055 people
- Sponsor
- Christiana Care Health Services
Open Angle Glaucoma
TF for the Prediction of Visual Field Progression
Baseline 24-hour SENSIMED Triggerfish (TF) recordings as well as functional and structural vision tests measured prospectively every 3 months over a 2-year period, will be used to model TF's ability to serve as a risk factor for…
- Trial name
- NCT03047239
- Testing
- SENSIMED Triggerfish
- Sponsor
- Sensimed AG