Clinical trials: Predictive Value of Tests, open to volunteers
Irritable Bowel Syndrome, Lactose Intolerant
Predictive Value of Hydrogen/Methane Lactose Breath Testing on the Therapeutic Effect of Lactose-free Diet in Moderate to Severe ROME IV IBS.
Lactose intolerance (LI) results from lactose malabsorption (LM) secondary to insufficient hydrolysis of the disaccharide lactose into galactose and glucose (Misselwitz 2019).
- Trial name
- NCT04974593
- Testing
- low fat diet
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Universitair Ziekenhuis Brussel
Fall Prevention, Falls (Accidents) in Old Age
Validation of the Self-Assessment for Falls in the Elderly (SAFE) Questionnaire to Assess the Risk of Falls in People Aged 60 or Over.
This single-centre, cross-sectional diagnostic study will determine whether the new self-completed Self-Assessment for Falls in the Elderly (SAFE) questionnaire can classify fall-risk level (low, moderate, high) in adults ≥ 60…
- Trial name
- SAFE (NCT06961812)
- Testing
- Questionnaire and Physical Exam, Safe Self-Administered Questionnaire
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Defibrillators, Implantable, Electrodes, Implanted
Slew Rate As a Predictor for Optimal Lead Fixation
The goal of this observational study is to identify the most reliable electrical parameter measured at the time of implantation that can predict optimal lead fixation and long-term lead performance in patients undergoing…
- Conditions
- Defibrillators, Implantable, Electrodes, Implanted, Pacemaker, Artificial, Predictive Value of Tests
- Trial name
- SLEW REGISTRY (NCT06842940)
- Where
- Italy
- Volunteers
- 516 people
- Sponsor
- Paolo Pastori, MD
Liver Cirrhosis, Early Allograft Dysfunction
Intraoperative Assessment of Microcirculatory Function Using Vascular Occlusion Test During Liver Transplantation
Early allograft dysfunction (EAD) remains one of the most important complications following orthotopic liver transplantation (OLT).
- Trial name
- NCT07658794
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Ippokrateio General Hospital of Thessaloniki
Chronic Liver Disease
Evaluating the Diagnostic and Predictive Value of Non-invasive Tests (NITs) on the Progression of Chronic Liver Disease.
Primary objective is to study the relevance of non-invasive test (NITs) in predicting disease stage (diagnostic biomarker) and outcome (predictive biomarker) in patients with suspected or established liver disease and cirrhosis.
- Trial name
- NITOutcomes (NCT05312853)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Johannes Gutenberg University Mainz
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
COPD, ILD
SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection
This is a prospective observational study that evaluates whether the Shuttle Walking Test (SWT) can predict postoperative symptoms, particularly dyspnea, in patients with chronic respiratory diseases undergoing lung resection.
- Conditions
- COPD, ILD, Bronchiectasis, Lung Cancer NOS
- Trial name
- SWEEP (NCT07102589)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Gestational Diabetes Mellitus (GDM), Pregnancy Complications
Glycemic Markers for Predicting Gestational Diabetes in Pregnant Women With Previous Bariatric Surgery
Gestational diabetes mellitus (GDM) is associated with significant maternal and fetal complications. The standard diagnostic test for GDM is the 75-gram oral glucose tolerance test (OGTT).
- Conditions
- Gestational Diabetes Mellitus (GDM), Pregnancy Complications, History of Bariatric Surgery
- Trial name
- BARI-GDM (NCT07517406)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Burak Deniz Aydoğdu
Adults Patients Undergoing Major Lung Resection in the Context of Lung Cancer
Predictive Value of a Preliminary Swallowing Test Compared to Postoperative Nasofibroscopy to Identify Vocal Cord Paralysis After Pulmonary Resection
The literature describes recurrent nerve damage during thoracic surgery as a fairly complication (5 to 31% of patients). This nerve damage leads to paresis or paralysis of the ipsilateral vocal cord.
- Trial name
- SwaLO (NCT05193240)
- Testing
- preliminary swallowing test
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Rouen
Pancreas Neoplasms, Pancreatic Neoplasms
Predictive Value of Transcriptome-based OncoTreat/Oncotarget and Organoid Testing in Metastatic Pancreatic Cancer.
Pancreatic cancer is burdened by a survival of barely 10% at 5 years. About 80% of new cases do not qualify for surgery due to either locally-advanced or metastatic disease.
- Conditions
- Pancreas Neoplasms, Pancreatic Neoplasms, Pancreatic Cancer Metastatic, Pancreatic Adenocarcinoma Metastatic
- Trial name
- NCT06615830
- Volunteers
- 185 people
- Sponsor
- Prof. Dr. med. Dres. h.c. Jan Schmidt, MME