Clinical trials: Predictors
End Stage Renal Disease, ESRD
Genetic Susceptibility to Cardiovascular Disease in Patients on Kidney Dialysis
This study, done in collaboration with Johns Hopkins University School of Public Health in Baltimore, Maryland, will examine the role of genes in the development of atherosclerotic cardiovascular disease (CVD) in patients…
- Trial name
- NCT00340119
- Where
- United States
- Volunteers
- 871 people
- Sponsor
- National Cancer Institute (NCI)
Procedural Sedation and Analgesia
PRedictors Of Maladaptive Behaviors in Children Undergoing Procedural SEDation
Procedural sedation for children outside of the operating room is a common practice in emergency departments, outpatient clinics, radiology suites, and dental offices for painful and anxiety-provoking procedures.
- Trial name
- PRoSEED (NCT07495826)
- Where
- 2 sites in Canada
- Volunteers
- 2,145 people
- Sponsor
- London Health Sciences Centre Research Institute
Cryptogenic Stroke, Atrial Fibrillation
Incidence and Predictors of Recurrent Stroke in Cryptogenic Stroke Patients With Atrial Fibrillation
Brief Summary: This study aimed to investigate the risk and factors that predict recurrent stroke in patients who initially had a stroke with no clear cause (called cryptogenic stroke) and were later found to have atrial…
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Recurrent Ischemic Stroke
- Trial name
- NCT07126184
- Testing
- Extended Cardiac Monitoring
- Where
- Pakistan
- Volunteers
- 109 people
- Sponsor
- Nangarhar University
Venous Thromboembolism, Pulmonary Embolism
Venous Thromboembolism in DM1
The risk for venous thromboembolism (VTE) in DM1 and in other inherited myopathies, which can lead to chronic immobilization, are unknown.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis, Myopathy
- Trial name
- DM1-VTE (NCT03141749)
- Volunteers
- 2,810 people
- Sponsor
- Institut de Myologie, France
Crohn's Disease, Enteral Nutrition
Predictors Favoring the Role of Exclusive Enteral Nutrition in Active Crohn's Disease
To idetify the factors favoring the use of enteral nutrition would be helpful to select preferred patients suitable for enteral nutrition.
- Trial name
- NCT02942511
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intrauterine Growth Restriction
FETAL PULMONARY VEIN AND UMBILICAL ARTERY PULSATILITY INDICES AS PREDICTORS OF FETAL GROWTH RESTRICTION IN DIABETIC AND HYPERTENSIVE PREGNANT WOMEN
Diabetic and hypertensive pregnant women attending at Kasr Alani for antenatal care were subjected to Complete History taking. All the participants were scanned using B mode sonography to determine the fetal biometric parameters…
- Trial name
- NCT06988436
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Cairo University
Encephalitis, Brain Diseases
Early Neurological Outcome in Pediatric Encephalitis
This prospective cohort study aims to identify baseline clinical, laboratory, and radiological factors at admission that are associated with early neurological outcomes in children with encephalitis admitted to Assiut University…
- Conditions
- Encephalitis, Brain Diseases, Neurologic Manifestations
- Trial name
- NCT07830927
- Volunteers
- 88 people
- Sponsor
- Assiut University
Breast Cancer, Invasive Breast Carcinoma
Tissue- and Serum-Derived Exosomal microRNAs as Predictors of Neoadjuvant Chemotherapy Response in Breast Cancer
This prospective observational study aims to evaluate whether exosomal microRNA profiles derived from tumor tissue and blood serum are associated with pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in…
- Conditions
- Breast Cancer, Invasive Breast Carcinoma, Exosomal microRNA, Neoadjuvant Chemotherapy Response
- Trial name
- ExoTSS-BC (NCT07500129)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlas University
Tibial Plateau Fracture
Predictors of Fracture-Dislocation in Schatzker IV Tibial Plateau Fractures: A Reproducible, Quantitative MRI-Based Injury-Pattern Analysis
This retrospective observational case-control study aims to evaluate imaging features and associated soft-tissue injury patterns in patients with Schatzker type IV tibial plateau fractures.
- Trial name
- fracture (NCT07481929)
- Testing
- Is it dislocation?
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Breast Neoplasms, Breast Cancer
IRELAND Trial: A Translational Biomarker and Exercise Study During Neoadjuvant Breast Cancer Therapy
The goal of this clinical trial is to learn whether a physiotherapy-led exercise programme delivered during treatment before surgery (neoadjuvant therapy) for breast cancer can improve physical fitness, quality of life, and how…
- Trial name
- IRELAND (NCT07799337)
- Testing
- Physiotherapist-Led Personalised Adaptive Exercise Programme
- Volunteers
- 250 people
- Sponsor
- National University of Ireland, Galway, Ireland
Gunshot Entry Wound
Predictors of Treatment Failure Among Patients With Gunshot Wounds and Post-traumatic Stress Disorder
The 82.1% treatment failure of post-traumatic stress disorder(PTSD), associated with gunshot wounds, is related to high incidence of chronic pain syndrome as well as resistance to the PTSD treatment.
- Trial name
- NCT04689022
- Testing
- Mississippi Scale for Combat-Related PTSD (M-PTSD), visual analogue scale (VAS), Douleur Neuropathique 4 questions (DN4)
- Volunteers
- 218 people
- Sponsor
- Vasyl' Horoshko
Cardiogenic Shock
Evaluation of Speckle Tracking Parameters as Predictors of Successful VA SPECKLE ECMO
Purpose of this study is to assess whether measurements obtained through speckle tracking (LV longitudinal and circumferential strain, RV longitudinal strain) can give additional information in identifying patients who develop…
- Trial name
- SPECKLE-ECMO (NCT03532529)
- Testing
- not applicable, it is an observational study
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Obesity
Mechanisms Underlying Predictors of Success From Obesity Surgery
The goal of this project is to identify predictors of success in the treatment of obesity after bariatric surgery. The specific aims of this proposal are to: 1.
- Trial name
- NCT02697253
- Testing
- Exendin 9-39 and Sitagliptin
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
High-risk Endometrial Cancer
Predictors of Recurrence for High Risk Endometrial Cancer Patients
This study will analyze whether there is any difference in recurrence and survival rates among the patients who received different adjuvant therapies.
- Trial name
- NCT04412902
- Testing
- adjuvant therapy
- Where
- Taiwan
- Volunteers
- 92 people
- Sponsor
- Far Eastern Memorial Hospital
Post-Intensive Care Syndrome (PICS), Critical Illness
Inflammatory and Genetic Predictors of Cognitive and Emotional Recovery After Critical Illness
Survivors of critical illness frequently develop persistent cognitive and emotional impairments, known as post-intensive care syndrome (PICS), which substantially impact quality of life and long-term recovery.
- Trial name
- CORE-ICU (NCT07659431)
- Volunteers
- 114 people
- Sponsor
- Corporacion Parc Tauli
Acute Kidney Injury
Incidence and Spectrum of Acute Kidney Injury in Cirrhotics and Assessment of New Biomarkers as Early Predictors of Acute Kidney Injury
500 patients with normal renal function will be prospectively studied and incidence, spectrum and natural history of AKI (Acute Kidney Injury) will be observed in them and in 200 patients with abnormal renal function fulfilling…
- Trial name
- NCT02016053
- Where
- India
- Volunteers
- 450 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Membranous Nephropathy
Autoreactive B Cells in Membranous Nephropathy
Membranous nephropathy (MN) is the most frequent cause of nephrotic syndrome (NS) in adults. The majority of MN patients show detectable circulating antibodies against the M-type phospholipase A2 receptor (PLA2R).
- Trial name
- PEPTIDE (NCT04095156)
- Testing
- In vitro assays.
- Where
- Italy
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cranial Neurosurgery
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery
Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU).
- Trial name
- HERO-PACU (NCT07443072)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Non-small Cell Lung Cancer Patients
Early Changes in Positron Emissions Tomography (PET/CT) Scan as Predictors of Clinical Outcome in NSCLC Treated With EGFR Tyrosin Kinase Inhibitors (TKI)
Erlotinib, an anti-cancer agent targeting the epidermal growth factor receptor (EGFR), is an active treatment of patients with non-small cell lung cancer (NSCLC).
- Trial name
- NCT02043002
- Testing
- 18F-FDG-PET scan
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- University of Aarhus
Systemic Lupus Erythematosus
Study of the Predictors of the Course and Early Outcome of Patients With Systemic Lupus Erythematosus: Nature Versus Nurture
OBJECTIVES: I. Continue yearly ascertainment visits of all patients of the established Lupus in Minority Populations: Nature vs Nurture (LUMINA) study cohort. II.
- Trial name
- NCT00006134
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Center for Research Resources (NCRR)