Clinical trials: Pregnancy, Physical Activity
End-stage Renal Disease (ESRD)
Effect of Lifestyle Intervention in Patients With Chronic Kidney Disease on Fitness and Immune Function
To assess the efficacy of a 6-month lifestyle intervention in patients with end-stage renal disease(ESRD), we plan to conduct a self-controlled clinical trial. 34 participants receiving chronic HD will be enrolled.
- Trial name
- NCT05649657
- Testing
- Cyclic aerobic and resistance training
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung Memorial Hospital
Kidney Failure
FREquent DIalysis & Markers of Cardiac Strain and Injury, Physical Fitness, Habitual Physical Activity & Quality of Life
Individuals with kidney failure are kept alive using dialysis machines designed to remove toxic substances and excess fluid from the blood.
- Trial name
- FREDI-CAL (NCT03925454)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Low Back Pain
The Effect Water-exercise on Low Back Pain and Sick Leave, Among Healthy Pregnant Women
To investigate the possible effect of an unsupervised water-exercise program, on the intensity of low back pain and the number of days spent on sick leave, among healthy pregnant women Our hypothesis is, that 45 minutes of water…
- Trial name
- WAPW (NCT02354430)
- Testing
- Water-exercise
- Where
- Denmark
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pregnancy Related, Pelvic Floor Disorders
Effects of Reformer Pilates in Pregnant Women
Pregnancy is known as a period associated with important physiological and psychological changes in women's lives. There is moderately sufficient evidence in the literature to recommend supplementing prenatal physical activity…
- Conditions
- Pregnancy Related, Pelvic Floor Disorders, Pain, Back, Pain, Neck
- Trial name
- NCT06777771
- Testing
- Reformer pilates exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Chronic Kidney Disease, Hypertension
Sympathetic Nerve Activity in Renal Failure
The primary purpose is to assess the role of sympathetic activation for the development and progression of chronic renal failure.
- Trial name
- SNS in CRF (NCT00892892)
- Testing
- Rilmenidine, Nitrendipine
- Where
- Germany
- Sponsor
- University of Erlangen-Nürnberg Medical School
Urinary Incontinence, Urinary Incontinence (UI)
Trial of NASHA Dx Urethral Bulking System
Prospective, randomized, single-blind study to evaluate the safety and efficacy of NASHA Dx investigational device compared to controlled device Bulkamid in adult women with mild, moderate and intrinsic sphincter deficiency (ISD).
- Conditions
- Urinary Incontinence, Urinary Incontinence (UI), Urinary Incontinence , Stress, Urinary Incontinence Due to Urethral Sphincter Incompetence
- Trial name
- NASHA-DX (NCT07850804)
- Testing
- NASHA Dx, Bulkamid
- Where
- 5 sites in United States
- Volunteers
- 314 people
- Sponsor
- Palette Life Sciences, Inc.
Polycystic Ovary Syndrome
Oral Contraceptive and Cardiovascular Risk in PCOS
Oral contraceptive therapy is routinely used for the treatment of menstrual disturbances of patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00593294
- Testing
- Physical exercise, OC - Drospirenone plus Ethynylestradiol, Vitamin, polyvitamins tablets
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federico II University
Multiple Sclerosis, Neurogenic Bladder Disorder
Effects of Pelvic Floor Strengthening and Relaxation Exercises in Women Diagnosed With Multiple Sclerosis
The aim of this study was to compare the effects of pelvic floor strengthening and relaxation exercises on lower urinary tract dysfunction (LUTD), depression and quality of life (QoL) in women with Multiple Sclerosis (WwMS).
- Conditions
- Multiple Sclerosis, Neurogenic Bladder Disorder, Pelvic Floor Muscle Exercise
- Trial name
- NCT07485556
- Testing
- Pelvic Floor Strengthening Exercises, Pelvic Floor Relaxation Exercises, Combined Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Advanced Solid Tumor, Metastatic Solid Tumor
A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and therapeutic activity of GI-108, as a single agent, in patients with advanced or metastatic solid tumors
- Conditions
- Advanced Solid Tumor, Metastatic Solid Tumor, Non-small Cell Lung Cancer (NSCLC), Head and Neck (HNSCC)
- Trial name
- NCT07172802
- Testing
- GI-108
- Where
- 3 sites in South Korea
- Volunteers
- 102 people
- Sponsor
- GI Innovation, Inc.
Sexual Dysfunction, Postmenopausal Symptoms
Examination of the Effects of Pelvic Floor Exercises on Vaginal and Sexual Health in Postmenopausal Women.
The purpose of this study; To investigate the effects of pelvic floor muscle exercises on vaginal and sexual health in postmenopausal women.
- Conditions
- Sexual Dysfunction, Postmenopausal Symptoms, Pelvic Floor Muscle Weakness
- Trial name
- NCT06294197
- Testing
- Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hatice Gulsah Kurne
Pregnancy
Exercise Training on Gait Pattern in Pregnancy
The research will be conducted with healthy pregnant women who applied to the Ege University Gynecology and Obstetrics Department Polyclinic, and were referred to the Sports Medicine Department.The study will consist of two…
- Trial name
- NCT05481983
- Testing
- Walk exercise, One-on-one clinical exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ege University
End Stage Renal Disease
Feasibility of an Interactive Tablet-based Exercise Program for People With Chronical Diseases
End Stage Renal Disease (ESRD) is a potential outcome of Chronic Kidney Disease (CKD) that requires renal replacement therapy in the form of dialysis or transplantation.Despite the encouraging benefits seen in PHD who exercised…
- Trial name
- TABEX-CD (NCT04076488)
- Testing
- Dividat Fit
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Zemp Damiano
Mental Health Wellness, Emotional Problem
Active Pregnancy. Mental and Emotional Health Care to Pregnant Woman During and After Coronavirus (COVID-19)
The complex process of pregnancy and childbirth can determine the future health of mother and child. It is the only vital process that involves the modification of practically all of a woman's body systems in order to sustain…
- Trial name
- GESTACTIVE (NCT05295264)
- Testing
- Moderate exercise program
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Gestational Diabetes
Preconception Lifestyle Interventions to Improve Future Metabolic Health (Before the Beginning)
The aim of this study is to investigate whether the combination of high intensity exercise and time restricted eating before and during pregnancy can reduce the risk of hyperglycaemia during pregnancy.
- Trial name
- NCT04585581
- Testing
- time-restricted eating, high intensity exercise, Standard Care
- Where
- Norway
- Volunteers
- 167 people
- Sponsor
- Norwegian University of Science and Technology
Advanced Solid Tumor
A Phase I Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of HC010 in Patients With Advanced Solid Tumors
This clinical trial is a multicenter, open, single-arm, non-randomized, dose-escalation and dose-expansion, phase I clinical study in patients with advanced recurrent or metastatic solid tumors.The goal of this study is to…
- Trial name
- NCT06307925
- Testing
- HC010
- Where
- China
- Volunteers
- 122 people
- Sponsor
- HC Biopharma Inc.
Blood Pressure
Pre-conception Interventions to Reduce Blood Pressure Before Pregnancy
The study proposes to evaluate the feasibility of a preconception intervention comprising two proven interventions for reducing blood pressure; Beetroot juice; a source of dietary nitrate which reduces BP by 8/4mmHg after 4…
- Trial name
- CONCEIVE 2 (NCT05299450)
- Testing
- Beet It shots, Exercise, Control group
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Pregnancy Complications
Effect of Direct Myofascial Release Technique Combined With Exercise on Round Ligament Pain During Pregnancy
Study's objective is to explore effect of combining direct myofascial release technique with therapeutic exercises on decreasing round ligament pain during pregnancy.The main question to be answered by this study: Does a…
- Trial name
- NCT07715422
- Testing
- Manual therapy technique named myofascial release combined with therapeutic exercises
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Polycystic Ovary Syndrome (PCOS)
Investigation of the Effectiveness of Spinal Stabilization Exercises Added to Aerobic Exercise in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a multisystemic disorder with metabolic and endocrine implications, commonly observed in women of reproductive age and characterized by hyperandrogenism, ovulatory dysfunction, and polycystic…
- Trial name
- NCT07871851
- Testing
- Aerobic Exercise, Spinal Stabilization Exercise
- Volunteers
- 20 people
- Sponsor
- Inonu University
Lupus Nephritis
Urinary G3BP as a Novel Biomarker in Lupus Nephritis
Estimation of urinary Galectin-3 binding protein (u-Gal-3BP) in patients with systemic lupus erythematosus with and without lupus nephritis and in glomerulonephritis for other kidney diseases, Find the relation of urinary…
- Trial name
- NCT06520670
- Testing
- Urinary galectin-3 binding protein
- Volunteers
- 70 people
- Sponsor
- Assiut University
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
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