Clinical trials: Pregnancy, Physical Activity
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic and debilitating urological complex of disorders characterized by symptoms of bladder pain or discomfort, mostly upon bladder filling, and often accompanied by…
- Trial name
- IC/BPS POC (NCT05141006)
- Testing
- BOTOX
- Where
- 43 sites in United States, Canada
- Volunteers
- 83 people
- Sponsor
- AbbVie
Advance Solid Tumors, Colon and Rectal Cancer
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-8989 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutations
This is a Phase 1 and Phase 2 study to evaluate the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of INV-8989 in patients with advanced solid tumors harboring KRAS G12D mutations.
- Conditions
- Advance Solid Tumors, Colon and Rectal Cancer, Non - Small Cell Lung Cancer NSCLC, Pancreatic Adenocarcinoma Advanced or Metastatic
- Trial name
- NCT07610798
- Testing
- INV-8989
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Shenzhen Ionova Life Sciences Co., Ltd.
Cancer Cervix Uterus, Precancerous Lesions
The Effect of Physical Activity and Abstain From Smoking on the Precancerous Lesion
In this proposed project,investigators will estimate the effect of physical activity and abstain from smoking on the regression of precancerous neoplasia.
- Conditions
- Cancer Cervix Uterus, Precancerous Lesions, Smoking
- Trial name
- NCT03093623
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 446 people
- Sponsor
- Taipei Medical University
Type2 Diabetes, Diabetic Kidney Disease
Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Diabetes
Type 2 diabetes is a chronic condition whose prevalence is increasing globally. Kidney disease is a key complication of diabetes and is among the most common cause of end-stage renal disease, requiring renal replacement therapy.
- Trial name
- ACTIDIANE (NCT03184662)
- Testing
- HIPA, Counseling PA
- Where
- 20 sites in Belgium, France
- Volunteers
- 178 people
- Sponsor
- Poitiers University Hospital
Hyperinsulinemia, Miscarriages
Maternal Lifestyle and Neonatal Hypoglycemia
tPA has a pivotal role in placentation, mediationg activation of growth factors, such as vascular endothelial growth factor and brain-derived neurotrophic factor, degradation of extracellular matrix and basement membrane…
- Conditions
- Hyperinsulinemia, Miscarriages, Pregnancy, Sedentary Lifestyle
- Trial name
- NCT01409382
- Testing
- Daily brisk walking plus a carbohydrate-restricted diet
- Where
- Brazil
- Volunteers
- 480 people
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Thrombotic Microangiopathies
Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies
The purpose of this study is to assess the safety, efficacy, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of OMS721 in patients with thrombotic microangiopathies (TMA).
- Trial name
- NCT02222545
- Testing
- OMS721
- Where
- 24 sites in United States, Belgium and 10 more
- Volunteers
- 58 people
- Sponsor
- Omeros Corporation
Moderate-severe Chronic Kidney Disease Not Treated With Dialysis, Diabetic Kidney Disease, HgbA1c Less Than 8.5
Exercise Study Testing Enhanced Energetics of Mitochondria Video Integrated Delivery of Activity Training in CKD
Skeletal muscle dysfunction (sarcopenia) is an under-recognized target organ complication of CKD with substantial adverse clinical consequences of disability, hospitalization, and death.
- Trial name
- ESTEEM-VIDA (NCT02923063)
- Testing
- Combined Aerobic and Resistance Exercise via videoconferencing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Davis
ESRD
COMEX Study for Dialysis Patients
The goal of the COMprehensive EXercise (COMEX) pilot study is to test feasibility, tolerability and adherence of this novel video-based intra-dialytic chair exercise program for hemodialysis patients over 3 months.
- Trial name
- COMEX (NCT03055299)
- Testing
- COMEX intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Postpartum, Pregnancy Related
Telehealth: Diaphragmatic vs. Pelvic Exercise in Postpartum Pregnancy-related Pelvic Girdle Pain
The goal of this interventional study is to compare investigate the short-term and long-term effects of 8-week real-time telehealth-based diaphragmatic breathing exercise and pelvic stabilization exercise on pain, disability, and…
- Conditions
- Postpartum, Pregnancy Related, Pelvic Girdle Pain
- Trial name
- NCT06284278
- Testing
- Diaphragmatic breathing retraining, Pelvic stabilization exercise, pelvic anatomy education
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- YI-JU TSAI
Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression
This clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of EphA2.
- Conditions
- Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer, Non-small Cell Lung Cancer
- Trial name
- NCT04180371
- Testing
- BT5528, Nivolumab
- Where
- 28 sites in United States, Belgium and 3 more
- Volunteers
- 288 people
- Sponsor
- BicycleTx Limited
Body Image, Physical Activity
Pregnant Elite Athletes and Pregnant Women Exercising With Moderate Intensity
The aim of this study is to 1. register possible changes to uteroplacental circulation in relation to physical tests, 2. to register energy and nutritional intake, relationship towards the body during pregnancy and during the…
- Conditions
- Body Image, Physical Activity, Exercise, Energy Intake
- Trial name
- NCT05042349
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Respiratory Distress Syndrome, Premature Infants
Effects of Non-invasive Ventilation With Helium-oxygen Mixture in Premature Infants With Respiratory Distress Syndrome
The use of a mixture of helium with oxygen (heliox) as a breathing gas may be beneficial due to its unique physical properties, such as low density and high carbon dioxide (CO2) diffusion coefficient.
- Trial name
- NCT04404816
- Testing
- heliox
- Where
- Poland
- Volunteers
- 23 people
- Sponsor
- Poznan University of Medical Sciences
Stress Urinary Incontinence, Pelvic Floor Muscle Weakness
Effectiveness of Pelvic Floor Muscle and Abdominal Training in Women With Stress Urinary Incontinence
The aim of this study was to investigate the effectiveness of pelvic floor muscle and abdominal training in reproductive-age patients with stress urinary incontinence.
- Trial name
- NCT03401983
- Testing
- Pelvic Floor Muscle Training and Abdominal Training, Pelvic Floor Muscle Training
- Volunteers
- 64 people
- Sponsor
- Trakya University
Obesity, Endometrial Carcinoma
Gentle Yoga and Dietary Counseling in Improving Physical Function and Quality of Life in Stage I-II Endometrial Cancer Survivors
This randomized clinical trial studies how well gentle yoga and dietary counseling lifestyle change effects physical function and quality of life of endometrial cancer survivors.
- Trial name
- NCT02465541
- Testing
- Gentle yoga therapy, counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Pregnancy Related, Mental Health Issue
Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
The goal of this research is to test if a prenatal yoga app can improve well-being in African American/Black (AA) pregnant women. The main questions it aims to answer are: 1.
- Conditions
- Pregnancy Related, Mental Health Issue, Discrimination, Racial, Stress
- Trial name
- NCT06353113
- Testing
- Down Dog Prenatal Yoga App
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Pregnancy, Weight Gain
Effectiveness of Video Messaging About Diet, Exercise and Weight Gain in Pregnancy in Regional and National Samples
The primary purpose of this study is to assess the responses of pregnant women and their social network to six videos about health in pregnancy.
- Trial name
- NCT02490579
- Testing
- Responses to Brief Video Messages (Facebook), Response to Brief Video Messages (Clinic), Response to Brief Video Messages (Social Network)
- Where
- United States
- Volunteers
- 1,670 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Exercise, Pregnancy Related
Cloud Platform Integration Model for Pregnant Women Exercise Consultation
To construct the platform for exercise counseling for pregnant women, and evaluate the effects of that telecare platform integration model for exercise consultation on exercise behaviors and prenatal health outcomes among…
- Trial name
- NCT06053151
- Testing
- exercise counselling
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Pregnant, Pregnancy-related Low Back and Pelvic Pain
Gulhane Military Medical Academy Ethical Committee Exercise Program for Pregnant Women With Low Back and Pelvic Pain
The aim of this study was to evaluate the effect of exercise programs on pregnant women with pregnancy-related Low Back and Pelvic Pain (LBPP).
- Trial name
- NCT02189356
- Testing
- exercise programme, standard care
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Obesity, Infertility, Female
Internet-based Intervention to Promote a Healthy Lifestyle on the Reproductive Parameters of Overweight and Obese Women
Obesity and overweight are among the problems that produce infertility. The combination of diet and exercise to achieve weight loss are currently considered an effective intervention for the improvement of reproductive parameters…
- Trial name
- HLRP-RCT (NCT04275869)
- Testing
- Healthy Lifestyle
- Where
- Spain
- Sponsor
- Cardenal Herrera University
Polycystic Ovary Syndrome, Obesity
Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome
The effects of a 16-week exercise training program on insulin resistance and adiposity in overweight/obese women with Polycystic ovary syndrome (PCOS).
- Trial name
- POLY (NCT01150539)
- Testing
- 16-week exercise training program, Control Group without PCOS
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pennington Biomedical Research Center
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